Search results for "Serp"

showing 10 items of 205 documents

Serpentine Gallery e Royal Parks annunciano l'inaugurazione di una nuova galleria nei Kensington Gardens

2010

Serperntine Gallery Royal Parks Londra
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Electrical and mechanical activity of mammalian heart muscle fibres treated with papaverine

1977

The action of papaverine on electrical and mechanical activity was investigated in ventricular and atrial heart muscle fibres from guinea-pigs and cats. 1. Papaverine (10−5 M–5×10−5M) had positive, negative or no inotropic effects in ventricular preparations; positive inotropic effects were not observed after pretreatment of the animals with reserpine. In atrial preparations, papaverine (2×10−5M) had a positive inotropic effect that was independent of endogenously stored catecholamines. 2. The effects of isoprenaline and dibutyryl cyclic AMP were potentiated by papaverine (10−5 M–2×10−5M). 3. The action potential duration was always prolonged by papaverine in ventricular as well as in atria…

Inotropemedicine.medical_specialtyReserpineGuinea PigsIn Vitro TechniquesMembrane PotentialsPapaverineIsoprenalineInternal medicinemedicineAnimalsDrug Interactionscardiovascular diseasesPharmacologyPapaverineCATSChemistryIsoproterenolHeartGeneral MedicinePapillary MusclesReserpineDibutyryl Cyclic AMPMyocardial ContractionMammalian heartEndocrinologyBucladesineCatscardiovascular systemAction potential durationmedicine.drugNaunyn-Schmiedeberg's Archives of Pharmacology
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Muscarinic inhibition of potassium-induced noradrenaline release and its dependence on the calcium concentration.

1975

1. Noradrenaline release from the isolated rabbit heart was evoked by perfusion with a medium containing 135 mM potassium and 17 mM sodium ions (high K+-low Na+). 2. The noradrenaline output in response to high K+-low Na+ was dose-dependently decreased by methacholine (0.625-320 muM) and this effect was reserved by atropine 1.44 mM. 3. Lowering the calcium concentration of high K+-low Na+ from 1.8-0.1125 mM decreased the noradrenaline output by 85%. The effect of methacholine, expressed as % inhibition of noradrenaline release, was potentiated by lowering of the calcium concentration. 4. Both at normal and lowered calcium concentrations the inhibitory action of methacholine was larger from …

AtropineMalemedicine.medical_specialtyReserpineTime FactorsSodiumPotassiumchemistry.chemical_elementAdrenergicCalciumchemistry.chemical_compoundNorepinephrineInternal medicineMuscarinic acetylcholine receptormedicinePressureAnimalsMethacholine CompoundsReceptors CholinergicPharmacologyCalcium metabolismMuscarineChemistryMyocardiumOsmolar ConcentrationSodiumGeneral MedicinePerfusionEndocrinologyPotassiumMethacholineCalciumFemaleRabbitsmedicine.drugNaunyn-Schmiedeberg's archives of pharmacology
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CONTROL OF PHYLLOCNISTIS CITRELLA STAINTON (LEPIDOPTERA: GRACILLARIIDAE) BY SELECTIVE INSECTICIDES AND BY MANIPULATION OF INDIGENOUS NATURAL ANTAGONI…

1999

Settore AGR/11 - Entomologia Generale E Applicatacontrollo biologico agrumi minatrice serpentina Eulophidae parassitoidi
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�ber den Wirkungsmechanismus von Reserpin

1959

business.industryMEDLINEGeneral MedicinePharmacologyReserpineMolecular medicineHuman geneticsMechanism of actionDrug DiscoveryMolecular MedicineMedicinemedicine.symptombusinessGenetics (clinical)medicine.drugKlinische Wochenschrift
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Heterologous expression, purification, crystallization and preliminary X-ray analysis of raucaffricine glucosidase, a plant enzyme specifically invol…

2006

Raucaffricine glucosidase (RG) is an enzyme that is specifically involved in the biosynthesis of indole alkaloids from the plant Rauvolfia serpentina. After heterologous expression in Escherichia coli cells, crystals of RG were obtained by the hanging-drop vapour-diffusion technique at 293 K with 0.3 M ammonium sulfate, 0.1 M sodium acetate pH 4.6 buffer and 11% PEG 4000 as precipitant. Crystals belong to space group I222 and diffract to 2.30 A, with unit-cell parameters a = 102.8, b = 127.3, c = 215.8 A.

RauvolfiaStereochemistryBiophysicsmedicine.disease_causeCrystallography X-RayBiochemistryRauwolfiachemistry.chemical_compoundBiosynthesisStructural BiologyRauvolfia serpentinaGeneticsmedicineEscherichia coliCloning MolecularEscherichia colichemistry.chemical_classificationIndole testbiologyCondensed Matter Physicsbiology.organism_classificationEnzymechemistryBiochemistryCrystallization Communicationsbiology.proteinHeterologous expressionCrystallizationGlucosidasesGlucosidases
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High-performance liquid chromatographic, capillary electrophoretic and capillary electrophoretic–electrospray ionisation mass spectrometric analysis …

2002

Systems for efficient separation of selected alkaloid groups by high performance liquid chromatography (HPLC), capillary electrophoresis (CE) and capillary electrophoresis coupled with electrospray ionisation mass spectrometry (CE-ESI-MS) are described. The optimized HPLC system was applied for the separation of 23 standard indole alkaloids as well as for qualitative and quantitative analyses of crude alkaloid extracts of Rauvolfia serpentina X Rhazya stricta hybrid cell cultures. The developed conditions for CE analysis proved to be efficient for separation of mixtures of standard indole and beta-carboline alkaloids. The described buffer system is also applicable in the combination of CE w…

Indole testSpectrometry Mass Electrospray IonizationElectrosprayChromatographyMolecular StructurebiologyIndole alkaloidChemistryOrganic ChemistryElectrophoresis CapillaryGeneral Medicinebiology.organism_classificationMass spectrometryBiochemistryHigh-performance liquid chromatographyAnalytical ChemistryAlkaloidsCapillary electrophoresisRauvolfia serpentinaQuantitative analysis (chemistry)Chromatography High Pressure LiquidJournal of Chromatography A
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Der Einflu� von Reserpin auf die Wirkung der ?Neuro-Sympathomimetica?

1960

PharmacologyHeart pharmacologyAction (philosophy)ChemistryPharmacology toxicologymedicineGeneral MedicineReserpinePharmacologymedicine.drugNaunyn-Schmiedeberg's Archiv f�r Experimentelle Pathologie und Pharmakologie
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Effectiveness of theophylline to increase cyclic AMP levels and force of contraction in electrically paced guinea-pig auricles. Comparison with isopr…

1977

The effects of theophylline (3×10−5 M–5×10−3 M), isoprenaline (10−6 M), excess calcium (7.2 mM) and ouabain (3×10−7 M) on force of contraction and c-AMP content were studied in electrically driven (frequency 3 Hz) left auricles isolated from guinea pigs pretreated with reserpine.

Malemedicine.medical_specialtyTime FactorsContraction (grammar)Guinea Pigschemistry.chemical_elementIn Vitro TechniquesCalciumOuabainGuinea pigTheophyllineInternal medicineIsoprenalineCyclic AMPmedicineAnimalsTheophyllineOuabainPharmacologyChemistryMyocardiumCardiac Pacing ArtificialIsoproterenolGeneral MedicineReserpineMyocardial ContractionPropranololC++ AMPEndocrinologyCalciumFemalemedicine.drugNaunyn-Schmiedeberg's Archives of Pharmacology
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Shotgun Proteomics of Isolated Urinary Extracellular Vesicles for Investigating Respiratory Impedance in Healthy Preschoolers

2021

Urine proteomic applications in children suggested their potential in discriminating between healthy subjects from those with respiratory diseases. The aim of the current study was to combine protein fractionation, by urinary extracellular vesicle isolation, and proteomics analysis in order to establish whether different patterns of respiratory impedance in healthy preschoolers can be characterized from a protein fingerprint. Twenty-one 3–5-yr-old healthy children, representative of 66 recruited subjects, were selected: 12 late preterm (LP) and 9 full-term (T) born. Children underwent measurement of respiratory impedance through Forced Oscillation Technique (FOT) and no significant differen…

MaleProteomePharmaceutical SciencePhysiologyUrineUrineProteomicsAminopeptidasesAnalytical Chemistry0302 clinical medicineDrug DiscoveryElectric ImpedanceMedicineRespiratory systemproteomic0303 health sciencesTripeptidyl-Peptidase 1urine fractionationExtracellular vesicleTripeptidyl peptidase IRespiratory Function Testsforced oscillation techniqueChemistry (miscellaneous)Child PreschoolMolecular MedicineFemaleUrinary systemReceptors Cell SurfaceArticlelcsh:QD241-441Extracellular Vesicles03 medical and health sciencesproteomicslcsh:Organic chemistryHumansNerve Growth FactorsPhysical and Theoretical ChemistryDipeptidyl-Peptidases and Tripeptidyl-PeptidasesEye ProteinsShotgun proteomicsAngiopoietin-Like Protein 2Serpins030304 developmental biologypreschooler healthy childrenbusiness.industryOrganic ChemistryCubilinAngiopoietin-like Proteins030228 respiratory systemThy-1 Antigensextracellular vesicleSerine Proteasesbusiness
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