Search results for "Signal"
showing 10 items of 6924 documents
Novel pathogenic mechanism of microbial metalloproteinases: liberation of membrane-anchored molecules in biologically active form exemplified by stud…
1996
Certain membrane-anchored proteins, including several cytokines and cytokine receptors, can be released into cell supernatants through the action of endogenous membrane-bound metalloproteinases. The shed molecules are then able to fulfill various biological functions; for example, soluble interleukin-6 receptor (sIL-6R) can bind to bystander cells, rendering these cells sensitive to the action of IL-6. Using IL-6R as a model substrate, we report that the metalloproteinase from Serratia marcescens mimics the action of the endogenous shedding proteinase. Treatment of human monocytes with the bacterial protease led to a rapid release of sIL-6R into the supernatant. This effect was inhibitable …
H<inf>&#x221E;</inf> filter design for time-delay Markovian jump systems
2013
This paper investigates the H ∞ filtering problem for discrete time-delay Markovian jump systems with application to networked control systems. To design a full-order filter which ensures the stochastic stability and a prescribed H ∞ performance level for the filtering error system, the Scaled Small Gain (SSG) Theorem is developed for stochastic systems. By employing a two-term approximation to delayed state variables, the original system is transformed into an input-output form consisting of two subsystems. Based on the developed SSG Theorem and the proposed Lyapunov-Krasovskii Functional (LKF), the scaled small gains of the subsystems are analyzed to establish a new condition for the exis…
Inversion of matrix pencils for generalized systems
1993
Abstract This paper clarifies the nature of the Leverrier-Faddeev algorithm for generalized and state-space systems. It presents useful diagrams for recursive computation of the coefficients of the characteristic polynomial and the coefficient matrices of the adjoint matrix for various matrix pencils. A simplified case covers recursive equations and diagrams for inversion of the second-order matrix pencil (Es2 + A1s + A0) where E may be singular. The appendix provides two examples of mechanical and heat exchange systems which can be described by the generalized models.
Strongly confined fluids: Diverging time scales and slowing down of equilibration
2016
The Newtonian dynamics of strongly confined fluids exhibits a rich behavior. Its confined and unconfined degrees of freedom decouple for confinement length $L \to 0$. In that case and for a slit geometry the intermediate scattering functions $S_{\mu\nu}(q,t)$ simplify, resulting for $(\mu,\nu) \neq (0,0)$ in a Knudsen-gas like behavior of the confined degrees of freedom, and otherwise in $S_{\parallel}(q,t)$, describing the structural relaxation of the unconfined ones. Taking the coupling into account we prove that the energy fluctuations relax exponentially. For smooth potentials the relaxation times diverge as $L^{-3}$ and $L^{-4}$, respectively, for the confined and unconfined degrees of…
Linear and nonlinear experimental regimes of stochastic resonance
2000
We investigate the stochastic resonance phenomenon in a physical system based on a tunnel diode. The experimental control parameters are set to allow the control of the frequency and amplitude of the deterministic modulating signal over an interval of values spanning several orders of magnitude. We observe both a regime described by the linear response theory and the nonlinear deviation from it. In the nonlinear regime we detect saturation of the power spectral density of the output signal detected at the frequency of the modulating signal and a dip in the noise level of the same spectral density. When these effects are observed we detect a phase and frequency synchronization between the st…
Optimal band selection for future satellite sensor dedicated to soil science
2009
Hyperspectral imaging systems could be used for identifying the different soil types from the satellites. However, detecting the reflectance of the soils in all the wavelengths involves the use of a large number of sensors with high accuracy and also creates a problem in transmitting the data to earth stations for processing. The current sensors can reach a bandwidth of 20 nm and hence, the reflectance obtained using the sensors are the integration of reflectance obtained in each of the wavelength present in the spectral band. Moreover, not all spectral bands contribute equally to classification and hence, identifying the bands necessary to have a good classification is necessary to reduce …
Transitions between imperfectly ordered crystalline structures: A phase switch Monte Carlo study
2012
A model for two-dimensional colloids confined laterally by ``structured boundaries'' (i.e., ones that impose a periodicity along the slit) is studied by Monte Carlo simulations. When the distance $D$ between the confining walls is reduced at constant particle number from an initial value ${D}_{0}$, for which a crystalline structure commensurate with the imposed periodicity fits, to smaller values, a succession of phase transitions to imperfectly ordered structures occur. These structures have a reduced number of rows parallel to the boundaries (from $n$ to $n\ensuremath{-}1$ to $n\ensuremath{-}2$, etc.) and are accompanied by an almost periodic strain pattern, due to ``soliton staircases'' …
Sub-threshold signal processing in arrays of non-identical nanostructures
2011
Weak input signals are routinely processed by molecular-scaled biological networks composed of non-identical units that operate correctly in a noisy environment. In order to show that artificial nanostructures can mimic this behavior, we explore theoretically noise-assisted signal processing in arrays of metallic nanoparticles functionalized with organic ligands that act as tunneling junctions connecting the nanoparticle to the external electrodes. The electronic transfer through the nanostructure is based on the Coulomb blockade and tunneling effects. Because of the fabrication uncertainties, these nanostructures are expected to show a high variability in their physical characteristics and…
TheINTEGRALspectrometer SPI: performance of point-source data analysis
2005
The performance of the SPI point-source data analysis system is assessed using a combination of simulations and of observations gathered during the first year of INTEGRAL operations. External error estimates are derived by comparing source positions and fluxes obtained from independent analyses. When the source detection significance provided by the SPIROS imaging reconstruction program increases from ∼10 to ∼100, the errors decrease as the inverse of the detection significance, with values from ∼10 to ∼1 arcmin in positions, and from ∼10 to ∼1 per cent in relative flux. These errors are dominated by Poisson counting noise. Our error estimates are consistent with those provided by the SPIRO…
TiFoSi: an efficient tool for mechanobiology simulations of epithelia
2020
[Motivation]: Emerging phenomena in developmental biology and tissue engineering are the result of feedbacks between gene expression and cell biomechanics. In that context, in silico experiments are a powerful tool to understand fundamental mechanisms and to formulate and test hypotheses.