Search results for "Simulation"
showing 10 items of 5095 documents
Un outil pour les politiques scolaires: "Prospective scolaire"
2012
Today, territorial, demographic evolutions can be quick, which encourages towns to reconsider the geography of public services. This is notably the case of General Councils that handle the localisation of public middle schools and establish school sectors. Carrying out these tasks requires taking into account several parameters: demographic dynamics, urban projects, social diversity within schools, and transportation conditions. The tool 'Prospective Scolaire' integrates these multiple data in order to help communities carry out their tasks.
Effects of Air Tightness Tests on Steel Thin-Wall Box Structures with Circular and Rectangular Cross Sections
2019
In this paper, the effects of air tightness tests on steel box structures with rectangular or circular cross sections typical of port cranes (legs, arms, and crosspieces) are analyzed. Legs and arms are generally made with elements with profiles having a square or rectangular cross section, while the diagonal struts are made with profiles having circular cross sections. To verify the air tightness of these elements, a necessary requirement to protect them from corrosion if they are not protected with other protection techniques, air tightness tests are performed. These tests, in the framework of durability tests, must be carried out while maintaining the structure elasticity well below the …
Aspen Plus process-simulation model: Producing biogas from VOC emissions in an anaerobic bioscrubber
2018
A process-simulation model for a novel process consisted of an anaerobic bioscrubber was developed in Aspen Plus®. A novel approach was performed to implement the anaerobic reactor in the simulation, enabling it to be connected to the scrubber. The model was calibrated and validated using data from an industrial prototype that converted air emissions polluted with volatile organic compounds with an average daily concentration of 1129 mgC Nm−3 into bioenergy for more than one year. The scrubber, which showed a removal efficiency within 83-93%, was successfully predicted with an average absolute relative error of 5.2 ± 0.08% using an average height-to-theoretical-plate value of 1.05 ± 0.08 m …
An algebraic multigrid based shifted-Laplacian preconditioner for the Helmholtz equation
2007
A preconditioner defined by an algebraic multigrid cycle for a damped Helmholtz operator is proposed for the Helmholtz equation. This approach is well suited for acoustic scattering problems in complicated computational domains and with varying material properties. The spectral properties of the preconditioned systems and the convergence of the GMRES method are studied with linear, quadratic, and cubic finite element discretizations. Numerical experiments are performed with two-dimensional problems describing acoustic scattering in a cross-section of a car cabin and in a layered medium. Asymptotically the number of iterations grows linearly with respect to the frequency while for lower freq…
A damping preconditioner for time-harmonic wave equations in fluid and elastic material
2009
A physical damping is considered as a preconditioning technique for acoustic and elastic wave scattering. The earlier preconditioners for the Helmholtz equation are generalized for elastic materials and three-dimensional domains. An algebraic multigrid method is used in approximating the inverse of damped operators. Several numerical experiments demonstrate the behavior of the method in complicated two-dimensional and three-dimensional domains. peerReviewed
An improved algorithm for thermal dynamic simulation of walls using Z-transform coefficients
2003
The Transfer Function Method (TFM), recommended by American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE), is one of the most modern tools available to solve heat transfer problems in building envelopes and environments. TFM utilises Z-transform to solve the equations system that describes the heat transfer in a multi-layered wall. Due to an analogy with an electric circuit, it is possible to write the equations system in a matrix suitable to be solved by computer. Authors carried out an analysis on an historical building placed in the south of Italy to test the reliability and the quality of the thermal dynamic simulation using TFM. The analysis is performed usi…
Waveguiding properties of a photonic crystal fiber with a solid core surrounded by four large air holes
2009
The polarization-dependent guiding properties of a hexagonal-lattice photonic crystal fiber with a solid-core surrounded by four large air holes are investigated. The appearance of a polarization dependent cutoff frequency, together with several parameters as the birefringence, the modal effective area, the group velocity dispersion and the polarization dependent loss are analyzed. A collection of fibers with different structural parameters were fabricated and characterized. An effective anti-guide structure from at least 450 nm to 1750 nm, a polarizing fiber with a polarization dependent loss of 16 dB/m at 1550 nm, and an endlessly singlemode polarization-maintaining fiber with group biref…
GRASP with exterior path-relinking and restricted local search for the multidimensional two-way number partitioning problem
2017
In this work, we tackle multidimensional two-way number partitioning (MDTWNP) problem by combining GRASP with Exterior Path Relinking. In the last few years, the combination of GRASP with path relinking (PR) has emerged as a highly effective tool for finding high-quality solutions for several difficult problems in reasonable computational time. However, in most of the cases, this hybridisation is limited to the variant known as interior PR. Here, we couple GRASP with the "exterior form" of path relinking and perform extensive experimentation to evaluate this variant. In addition, we enhance our GRASP with PR method with a novel local search method specially designed for the MDTWNP problem. …
Identification of a new series of amides as non-covalent proteasome inhibitors
2014
Proteasome inhibition has emerged as an important therapeutic strategy for the treatment of multiple myeloma (MM) and some forms of lymphoma, with potential application in other types of cancers. 20S proteasome consists of three different catalytic activities known as chymotrypsin-like (ChT-L), trypsin-like (T-L), and, post-glutamyl peptide hydrolyzing (PGPH) or caspase-like (C-L), which are located respectively on the β5, β2, and β1 subunits of each heptameric β rings. Currently a wide number of covalent proteasome inhibitors are reported in literature; however, the less widely investigated non-covalent inhibitors might be a promising alternative to employ in therapy, because of the lack o…
Synthesis and biological activities of a new class of heat shock protein 90 inhibitors, designed by energy-based pharmacophore virtual screening
2013
The design through energy-based pharmacophore virtual screening has led to aminocyanopyridine derivatives as efficacious new inhibitors of Hsp90. The synthesized compounds showed a good affinity for the Hsp90 ATP binding site in the competitive binding assay. Moreover, they showed an excellent antiproliferative activity against a large number of human tumor cell lines. Further biological studies on the derivative with the higher EC50 confirmed its specific influence on the cellular pathways involving Hsp90.