Search results for "Single"

showing 10 items of 4920 documents

Magnetic hysteresis up to 80 kelvin in a dysprosium metallocene single-molecule magnet

2018

Breaking through the nitrogen ceiling Single-molecule magnets could prove useful in miniaturizing a wide variety of devices. However, their application has been severely hindered by the need to cool them to extremely low temperature using liquid helium. Guo et al. now report a dysprosium compound that manifests magnetic hysteresis at temperatures up to 80 kelvin. The principles applied to tuning the ligands in this complex could point the way toward future architectures with even higher temperature performance. Science , this issue p. 1400

agnetic propertiesmagneettiset ominaisuudetchemistry.chemical_elementorganometalliyhdisteet010402 general chemistry01 natural sciencesMagnetizationchemistry.chemical_compoundMoleculeSingle-molecule magnetsingle-molecule magnetsrare earth metalsta116MultidisciplinaryCondensed matter physics010405 organic chemistryrganometallic compoundskompleksiyhdisteetmetallocenesharvinaiset maametallitMagnetic hysteresismagnetic hysteresisNanomagnet0104 chemical scienceschemistryMagnetDysprosiumQD0146MetalloceneScience
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Empirical analyses of European intellectual property rights institutions

2018

This dissertation consists of introduction chapter and five empirical studies on European intellectual property rights institutions. Chapters 2, 3 and 4 are micro-level studies and the perspective shifts to macro-level in Chapters 5 and 6. Chapters 2, 3, 5 and 6 analyze two-tiered patent systems and Chapter 4 focuses on design rights. Chapter 2 analyzes the choice between patent and utility model protection among German firms. The results indicate that larger firms are more likely to use both protection methods and that a short life cycle of products and services is associated with an increased likelihood to use utility models. Chapter 3 analyzes the role of utility models in patent filing …

aktiivisuusself-selectionkilpailukykyinstituutiotmallioikeuspatentointipatenttijärjestelmäthyödyllisyysmallittwo-tiered patent systemväitöskirjatutility modelinnovaatiotpatentkaksitasoinen patenttijärjestelmäimmateriaalioikeusdesign rightintellectual property rightEuropean Single MarketEurooppasecond tier patent
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Photodegradation of Brilliant Green Dye by a Zinc bioMOF and Crystallographic Visualization of Resulting CO2

2021

We present a novel bio-friendly water-stable Zn-based MOF (1), derived from the natural amino acid L-serine, which was able to efficiently photodegrade water solutions of brilliant green dye in only 120 min. The total degradation was followed by UV-Vis spectroscopy and further confirmed by single-crystal X-ray crystallography, revealing the presence of CO2 within its channels. Reusability studies further demonstrate the structural and performance robustness of 1.

amino acids-derived ligandsPharmaceutical Sciencechemistry.chemical_elementOrganic chemistry02 engineering and technologyZincphotocatalytic degradation010402 general chemistry01 natural sciencesArticleAnalytical Chemistrychemistry.chemical_compoundQD241-441Drug Discoverysingle-crystal X-ray crystallographyPhysical and Theoretical ChemistrySpectroscopyPhotodegradationmetal-organic frameworksReusabilitychemistry.chemical_classificationwater remediation021001 nanoscience & nanotechnology0104 chemical sciencesAmino acidCrystallographyBrilliant greenchemistryChemistry (miscellaneous)Molecular MedicineDegradation (geology)Metal-organic framework0210 nano-technologyMolecules
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A two-stage genome-wide association study of sporadic amyotrophic lateral sclerosis

2009

The cause of sporadic amyotrophic lateral sclerosis (ALS) is largely unknown, but genetic factors are thought to play a significant role in determining susceptibility to motor neuron degeneration. To identify genetic variants altering risk of ALS, we undertook a two-stage genome-wide association study (GWAS): we followed our initial GWAS of 545 066 SNPs in 553 individuals with ALS and 2338 controls by testing the 7600 most associated SNPs from the first stage in three independent cohorts consisting of 2160 cases and 3008 controls. None of the SNPs selected for replication exceeded the Bonferroni threshold for significance. The two most significantly associated SNPs, rs2708909 and rs2708851 …

amyotrophic lateral sclerosisLinkage disequilibriumPopulationamyotrophic lateral sclerosis; genetics; GWASingle-nucleotide polymorphismGenome-wide association studyBiologyGWAPolymorphism Single Nucleotide03 medical and health sciences0302 clinical medicineGenotypeGeneticsmedicineHumansPolymorphismAmyotrophic lateral sclerosiseducationMolecular BiologyGenetics (clinical)030304 developmental biologyGenetics0303 health scienceseducation.field_of_studyGenomeSLA wide genome screeningGenome HumanAssociation Studies ArticlesCase-control studySingle NucleotideGeneral MedicineOdds ratiomedicine.diseaseSettore MED/26 - NEUROLOGIAAmyotrophic Lateral Sclerosis; genetics Case-Control Studies Genome; Human Genome-Wide Association Study Humans Polymorphism; Single NucleotideCase-Control Studies030217 neurology & neurosurgeryHumanGenome-Wide Association StudyHuman Molecular Genetics
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Unveiling the Different Reactivity of Bent and Linear Three-Atom-Components Participating in [3 + 2] Cycloaddition Reactions

2021

The reactivity of a series of pairs of bent and linear three-atom-component (B-TACs and L-TACs) participating in [3 + 2] cycloaddition (32CA) reactions towards ethylene and electrophilic dicyanoethylene (DCE) have been studied within the Molecular Electron Density Theory. While the pseudodiradical structure of B-TACs changes to that of pseudoradical or carbenoid L-TACs upon dehydrogenation, zwitterionic B-TACs remain unchanged. Conceptual Density Functional Theory (CDFT) indices characterize five of the nine TACs as strong nucleophiles participating in polar reactions towards electrophilic ethylenes. The activation energies of the 32CA reactions with electrophilic DCE range from 0.5 to 22.0…

analytical_chemistry[3 + 2] cycloaddition reactionsOrganic chemistrychemical and pharmacologic phenomena010402 general chemistry01 natural sciencesQD241-441stomatognathic systemNucleophileComputational chemistrySingle bondReactivity (chemistry)skin and connective tissue diseasesCarbenoid010405 organic chemistryChemistrymolecular electron density theoryRegioselectivity16. Peace & justiceCycloaddition0104 chemical sciencesreactivitystomatognathic diseasesbent and linear three-atom-componentsregioselectivityElectrophileDensity functional theoryOrganics
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Prediction model for aneuploidy in early human embryo development revealed by single-cell analysis.

2014

Aneuploidies are prevalent in the human embryo and impair proper development, leading to cell cycle arrest. Recent advances in imaging and molecular and genetic analyses are postulated as promising strategies to unveil the mechanisms involved in aneuploidy generation. Here we combine time-lapse, complete chromosomal assessment and single-cell RT–qPCR to simultaneously obtain information from all cells that compose a human embryo until the approximately eight-cell stage (n=85). Our data indicate that the chromosomal status of aneuploid embryos (n=26), including those that are mosaic (n=3), correlates with significant differences in the duration of the first mitotic phase when compared with e…

animal structuresCellular differentiationGeneral Physics and AstronomyAneuploidyBiologyModels BiologicalGeneral Biochemistry Genetics and Molecular BiologyArticleTranscriptomeSingle-cell analysismedicineHumansGenetic TestingMitosisCell ProliferationGeneticsMultidisciplinaryGene Expression ProfilingGene Expression Regulation DevelopmentalEmbryoCell DifferentiationGeneral Chemistrymedicine.diseaseAneuploidyGene expression profilingembryonic structuresPloidyNature communications
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Development of anode supported Single Chamber Solid Oxide Fuel Cells running in air/methane mixture

2013

International audience; Single Chamber Solid Oxide Fuel Cells (SCFC) show a growing interest and are the concern of more and more papers. In such device, anode and cathode are ex-posed to a gas mixture of fuel (hydrocarbon) and oxidant (air) so that no more sealing with electrolyte is necessary. Their operating principle is based on the different catalytic activities of anode and cathode: Ideally, the anode has to be active for the oxidation of fuel while the cathode should present only a strong electro-activity for oxygen reduction. In this paper, we present the development of an anode supported SCFC device running in air/methane mixture characterized by their volume ratio, Rmix = CH4/O2.

anode[SPI.GPROC] Engineering Sciences [physics]/Chemical and Process EngineeringNiO reductionair/methane mixture[ SPI.GPROC ] Engineering Sciences [physics]/Chemical and Process Engineering[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringSingle Chamber Solid Oxide Fuel CellsSCFC
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ATLAS Inner Detector alignment and analysis of the Wtb vertex structure with single top quarks

2018

Esta tesis puede ser dividida en dos partes diferentes: La primera trata sobre el alineamiento del detector interno de ATLAS, y la segunda sobre el estudio de la estructura del vértice Wtb mediante el uso de quarks top producidos en solitario. La primera parte presenta las técnicas utilizadas para alinear el detector interno de ATLAS, así como las mejoras implementadas en algoritmo de alineamiento durante el Run-II del LHC. Durante la toma de datos, tienen lugar en el detector interno diversos movimientos y deformaciones dinámicos que comprometen la calidad de los datos recogidos. Los dos más relevantes son un movimiento vertical del detector de Píxeles, y el combado del IBL. En el alineami…

anomalous couplingsweak interaction221502 - Física experimental de altas energíasalignment221500 - Física de altas energíasHigh Energy Physics::ExperimentATLASDetectors and Experimental TechniquesInner Detectortop quarksingle top220807 - Física de partículas
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Chronic Total Coronary Artery Occlusion Recanalisation with Percutaneous Coronary Intervention — Single Centre 10-Year Experience

2018

Abstract Coronary artery chronic total occlusions (CTO) are common — approximately one-third of patients with significant coronary artery disease on angiography have at least 1 CTO. Invasive treatment of these lesions still remain a major challenge for interventional cardiology due to their complexity. Historically, success rates have improved to about 60–70% by using only the traditional antegrade approach. The results have dramatically improved during the last decade after more widespread application of new retrograde techniques. The aim of our study was to review and analyse single hospital experience in CTO invasive treatment and to evaluate the long-term results. A total of 519 patient…

antegrade and retrograde approachmedicine.medical_specialtyMultidisciplinaryGeneral interestSciencemedicine.medical_treatmentQinvasive treatmentPercutaneous coronary intervention030204 cardiovascular system & hematologyChronic Total Coronary Artery Occlusion03 medical and health sciencesSingle centre0302 clinical medicinechronic total occlusionsInternal medicinemedicineCardiology030212 general & internal medicineProceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences.
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Polarisation dependent Raman study of single-crystal nickel oxide

2011

Abstract The magnetic domain structure and Raman scattering have been studied in NiO single-crystals with three different (100), (110) and (111) orientations. Twin-domain structure was observed in NiO(100) and NiO(110) single-crystals using cross-polarized optical microscopy. We found that the ratio of the two-magnon (at 1500 cm−1) to the two-phonon (2LO, at 1100 cm−1) Raman bands intensity is sensitive in a particular way to the type of the twin-domain pattern.

antiferromagnetic domainsMaterials scienceMagnetic domainNickel oxidePhysicsQC1-999Non-blocking I/OAnalytical chemistryGeneral Physics and Astronomyniomagnonslaw.inventionsymbols.namesakeX-ray Raman scatteringNuclear magnetic resonanceOptical microscopelawsymbolsRaman spectroscopyraman scatteringSingle crystalRaman scatteringOpen Physics
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