Search results for "SoMe"

showing 10 items of 5114 documents

Depletion ofL-arginine induces autophagy as a cytoprotective response to endoplasmic reticulum stress in human T lymphocytes

2012

PMCID: PMC3494587

X-Box Binding Protein 1Proteasome Endopeptidase ComplexProgrammed cell deathXBP1CD3 ComplexMAP Kinase Signaling SystemRNA SplicingT-LymphocytesT cellDown-RegulationApoptosisRegulatory Factor X Transcription FactorsUbiquitin-Activating EnzymesProtein Serine-Threonine KinasesBiologyArginineLymphocyte ActivationAutophagy-Related Protein 7Jurkat cellsJurkat CellsEndoribonucleasesAutophagymedicineHumansMolecular BiologyCell ProliferationTOR Serine-Threonine KinasesAutophagyMembrane ProteinsCell BiologyBECN1Endoplasmic Reticulum StressG1 Phase Cell Cycle CheckpointsBasic Research Paper3. Good healthCell biologyDNA-Binding Proteinsmedicine.anatomical_structureCytoprotectionApoptosisUnfolded protein responseBeclin-1MitogensApoptosis Regulatory ProteinsLysosomesProto-Oncogene Proteins c-aktTranscription FactorsAutophagy
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cis-[(η5-C5H5)Fe(η1-CO)(μ-CO)]2, the poor relative between cis and trans tautomers. A theoretical study of the gas-phase Fe L3-edge and C and O K-edg…

2021

The relative stability of trans-[(η5-C5H5)Fe(η1-CO)(μ-CO)]2 (trans-I) and cis-I tautomers in a vacuum and in solvents with different dielectric constants (e) has been investigated by exploiting density functional theory (DFT). Theoretical results indicate that, in agreement with experimental evidence, trans-I is more stable than cis-I in a vacuum (∼1.5 kcal mol−1; e = 1), while the opposite is true in media with e > 7. Differently from solution, DFT outcomes pertaining to the vapor-phase cis-I ⇆ trans-I equilibrium at T = 368 K, the temperature at which the Fe L2,3-edges and the C and O K-edge X-ray absorption spectroscopy (XAS) data of I have been recorded, ultimately indicate the trans-I …

X-ray absorption spectroscopyMaterials scienceK-edgeAbsorption spectroscopyGeneral Physics and AstronomyPhysical chemistryDensity functional theoryDielectricPhysical and Theoretical ChemistryTautomerSpectral lineCis–trans isomerismPhysical Chemistry Chemical Physics
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Thermodynamic and Kinetic Modeling of Co-utilization of Glucose and Xylose for 2,3-BDO Production by Zymomonas mobilis

2021

Prior engineering of the ethanologen Zymomonas mobilis has enabled it to metabolize xylose and to produce 2,3-butanediol (2,3-BDO) as a dominant fermentation product. When co-fermenting with xylose, glucose is preferentially utilized, even though xylose metabolism generates ATP more efficiently during 2,3-BDO production on a BDO-mol basis. To gain a deeper understanding of Z. mobilis metabolism, we first estimated the kinetic parameters of the glucose facilitator protein of Z. mobilis by fitting a kinetic uptake model, which shows that the maximum transport capacity of glucose is seven times higher than that of xylose, and glucose is six times more affinitive to the transporter than xylose.…

Xylose isomeraseenzyme protein cost analysisHistologythermodynamics analysisBiomedical Engineeringkinetic modelsBioengineeringXyloseZymomonas mobilis03 medical and health scienceschemistry.chemical_compoundXylose metabolismbiofuel productionOriginal Research030304 developmental biology0303 health sciencesbiology030306 microbiologyZymomonas mobilisBioengineering and BiotechnologyMetabolismbiology.organism_classificationFlux balance analysisBiochemistrychemistry23-butanediolFermentationdynamic flux balance analysisFlux (metabolism)TP248.13-248.65BiotechnologyFrontiers in Bioengineering and Biotechnology
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Genetic sex determination and sex-specific lifespan in tetrapods – evidence of a toxic Y effect

2020

ABSTRACTSex-specific lifespans are ubiquitous across the tree of life and exhibit broad taxonomic patterns that remain a puzzle, such as males living longer than females in birds and vice versa in mammals. The prevailing “unguarded-X” hypothesis (UXh) explains this by differential expression of recessive mutations in the X/Z chromosome of the heterogametic sex (e.g., females in birds and males in mammals), but has only received indirect support to date. An alternative hypothesis is that the accumulation of deleterious mutations and repetitive elements on the Y/W chromosome might lower the survival of the heterogametic sex (“toxic Y” hypothesis). Here, we report lower survival of the heterog…

Z chromosomeZoologyMammalKaryotypeDifferential expressionBiologySex specificHeterogametic sexW chromosome
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Polarization transfer via field sweeping in parahydrogen-enhanced nuclear magnetic resonance.

2019

<div><br></div><div><table><tr><td>We show that in a spin system of two magnetically inequivalent protons coupled to a heteronucleus such as 13C, an adiabatic magnetic field sweep, passing through zero field, transfers proton singlet order into magnetization of the coupled heteronucleus. This effect is potentially useful in parahydrogen-enhanced nuclear magnetic resonance, and is demonstrated on singlet-hyperpolarized [1-13C]maleic acid, which is prepared via the reaction between [1-13C]acetylene dicarboxylic acid and para-enriched hydrogen gas. The magnetic field sweeps are of microtesla amplitudes, and have durations on the order of seconds. We sh…

Zero field NMRMaterials science010304 chemical physicsMaleic acidHydrogenField (physics)ProtonGeneral Physics and Astronomychemistry.chemical_element010402 general chemistryPolarization (waves)Spin isomers of hydrogen01 natural sciences0104 chemical sciencesMagnetic fieldchemistry.chemical_compoundMagnetizationNuclear magnetic resonancechemistry0103 physical sciencesSinglet statePhysical and Theoretical ChemistryThe Journal of chemical physics
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Hyperbolic isometries versus symmetries of links

2009

We prove that every finite group is the orientation-preserving isometry group of the complement of a hyperbolic link in the 3-sphere.

[ MATH.MATH-GT ] Mathematics [math]/Geometric Topology [math.GT]Pure mathematicsHyperbolic groupHyperbolic linkTotally geodesic surfaces01 natural sciencesRelatively hyperbolic group57M60Mathematics - Geometric Topology[MATH.MATH-GT]Mathematics [math]/Geometric Topology [math.GT]0103 physical sciencesFOS: Mathematics0101 mathematicsMathematics[MATH.MATH-GT] Mathematics [math]/Geometric Topology [math.GT]Hyperbolic linksHyperbolic space010102 general mathematicsHyperbolic 3-manifoldHyperbolic manifoldGeometric Topology (math.GT)Algebra010307 mathematical physicsGeometry and TopologyIsometry groupHyperbolic Dehn surgeryHyperbolic Dehn surgeryTopology and its Applications
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Investigation of the vibrational dynamics of the HCN/CNH isomers through high order canonical perturbation theory

2000

International audience; Molecular vibrations of the molecule HCN/CNH are examined using a combination of a minimum energy path Hamiltonian and high order canonical perturbation theory , as suggested in a recent work [D. Sugny and M. Joyeux, J. Chem. Phys. 112, 31 (2000)]. In addition, the quantum analog of the classical CPT is presented and results obtained therefrom are compared to the classical ones. The MEP Hamiltonian is shown to provide an accurate representation of the original potential energy surface and a convenient starting point for the CPT. The CPT results are subsequently used to elucidate the molecular dynamics: It appears that the isomerization dynamics of HCN/CNH is very tri…

[ PHYS.QPHY ] Physics [physics]/Quantum Physics [quant-ph]010304 chemical physicsChemistryGeneral Physics and Astronomy010402 general chemistry01 natural sciencesMolecular physics0104 chemical sciencesMolecular dynamicssymbols.namesake[PHYS.QPHY]Physics [physics]/Quantum Physics [quant-ph]Computational chemistryMolecular vibration0103 physical sciencesPotential energy surfacesymbolsMoleculePhysical and Theoretical ChemistryHigh orderHamiltonian (quantum mechanics)QuantumIsomerization[PHYS.QPHY] Physics [physics]/Quantum Physics [quant-ph]
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Interfaces électrochimiques et couches minces sondées par ellipsométrie

2020

Spectroscopic ellipsometry (SE) is a non-invasive, non-destructive, and contactless optical technique which is based on the change in the polarization state of light as it is typically reflected from a thin film sample. Often seen primarily as ex situ or of particularly helpful interest to control in situ vacuum growth processes, SE can also be promoted as an analytical tool to diagnose electrolyte-electrode interface during wet processes. I will mainly highlight in this document my researches contributions in this field: (i) the very early growth stages of bismuth telluride electrodeposition, (ii) the physico-chemical properties of oxides grown in the early regime of plasma electrolytic ox…

[CHIM.MATE] Chemical Sciences/Material chemistryelectrochemistryélectrochimie[PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]ellipsométrie[CHIM.MATE]Chemical Sciences/Material chemistry[PHYS.COND.CM-MS] Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci]ellipsometry
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Decay and Fission Hindrance of Two- and Four-Quasiparticle K Isomers in 254Rf

2015

International audience; Two isomers decaying by electromagnetic transitions with half-lives of 4.7(1.1) and 247(73) mu s have been discovered in the heavy (254)Rf nucleus. The observation of the shorter-lived isomer was made possible by a novel application of a digital data acquisition system. The isomers were interpreted as the K-pi = 8(-), nu(2)(7/2(+)[624]; 9/2(-)[734]) two-quasineutron and the K-pi = 16(+), 8(-)nu(2)(7/2(+)[624]; 9/2(-)[734] circle times 8(-)pi(2) (7/2(-)[514]; 9/2(+)[624]) four-quasiparticle configurations, respectively. Surprisingly, the lifetime of the two-quasiparticle isomer is more than 4 orders of magnitude shorter than what has been observed for analogous isomer…

[PHYS]Physics [physics]General PhysicsNO-254nuclear isomersEngineeringNUCLEISTATESPhysical Sciencesrutherfordium[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]FM-250Mathematical Sciences
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Morphological and chemical dynamics upon electrochemical cyclic sodiation of electrochromic tungsten oxide coatings extracted by in situ ellipsometry.

2020

The sodiation–desodiation process of sputtered amorphous electrochromic tungsten oxide coatings in an aqueous-based medium was simultaneously monitored over 99 cycles by cyclic voltammetry and in situ spectroscopic ellipsometry. This allowed extracting the evolution of optical and geometrical parameters upon cycling. The resulting electrochemical coloring-bleaching process was dynamically fitted in the 1.8–2.8 eV optical range with a four-phase model including a constrained spline parametrization of the dielectric function. This allows real time access to thickness, surface roughness, and dielectric function of N a x W O 3 . The temporal evolution of the latter in the fully colored state wa…

[PHYS]Physics [physics]Materials sciencebusiness.industryScanning electron microscopeAnalytical chemistryCharge density01 natural sciencesAtomic and Molecular Physics and OpticsAmorphous solid010309 opticsOpticsEllipsometryElectrochromism0103 physical sciencesContent (measure theory)Surface roughnessElectrical and Electronic EngineeringCyclic voltammetrybusinessEngineering (miscellaneous)Applied optics
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