Search results for "SoMe"
showing 10 items of 5114 documents
Enantiodifferentiation of N-benzyloxycarbonylaminophosphonic and phosphinic acids and their esters using cyclodextrins by means of capillary electrop…
2005
Capillary electrophoresis was successfully applied for separation of the enantiomers of N-benzyloxycarbonyl-alpha-aminophosphonic and alpha-aminophosphinic acids as well as their ethyl and phenyl monoesters with the use of a range of commercially available cyclodextrins (alpha, beta and hydroxypropyl-gamma-cyclodextrins) as chiral selectors. The dependence of effectiveness of separation on type and concentration of these chiral selectors as well as on pH of background electrolyte was examined in some detail.
Separation of aminoalkanephosphonic acid enantiomers by indirect UV detection capillary electrophoresis with application of cyclodextrins.
2003
Indirect UV detection capillary electrophoresis (CE) was used for the separation of aminoalkanephosphonic acid (AP) enantiomers by applying commercially available cyclodextrins as chiral discriminators. The results show that the separation of the enantiomers depends on pH of the background electrolyte, the molar ratio of cyclodextrin to aminophosphonic acid, and on the type of the applied chiral selector. Optimization of process conditions allowed enantiomeric baseline separation or partial separation of 12 out of 14 alpha-aminophosphonic acids studied. This type of CE might therefore be successfully used for routine determination of enantiomeric purity of aminophosphonic acids.
Tiempos felices: Transformaciones en las tecnologías psicológicas de gobierno de la subjetividad
2020
This paper traces some inflections in the psy disciplines? discourses and technologies for the government of subjectivity during the last decades. It is focused on exploring different mechanisms through which psychological disciplines ?their discourses, techniques and practices? penetrate social life and contribute to establishing subject models consistent with transformations in the political and economic rationalities of late capitalism. Drawing on previous research in the field of gender politics and happiness discourses in the pop psychological culture, I track a line with three moments: i) the production of psychological individuality and identity normalization; ii) the proliferation o…
Patterns of Puffing Activity in the Polytene Chromosomes of Drosophila Subobscura
1982
The puffs and Balbiani rings are the visible expression of sites of genetic activity (Beerman, 1952). Since Beermann’s original hypothesis, puffing patterns for several species of Diptera have been described. Thus for the genus Drosophila, Ashburner (1967, 1969a and 1969b) has reported the puffing pattern of Drosophila melanogaster and Drosophila simulans, Beredens (1965) of Drosophila hydei, and Moriwaki and Ito (1969) of Drosophila ananassae. In a previous paper Frutos and Latorre (1981) have determined puffing patterns of the J and U chromosomes of Drosophila subobscura. This species shows a rich chromosomal polymorphism and the puffing pattern of several chromosomal rearrangements of th…
Computational investigations of 18-electron triatomic sulfur–nitrogen anions
2018
MRCI-SD/def2-QZVP and PBE0/def2-QZVP calculations have been employed for the analysis of geometries, stabilities, and bonding of isomers of the 18-electron anions N2S2−, NS2−, and NSO−. Isomers of the isoelectronic neutral molecules SO2, S2O, S3, and O3 are included for comparison. The sulfur-centered acyclic NSN2−, NSS−, and NSO− anions are the most stable isomers of their respective molecular compositions. However, the nitrogen-centered isomers SNS− and SNO− lie close enough in energy to their more stable counterparts to allow their occurrence. The experimental structural information, where available, is in good agreement with the optimized bond parameters. The bonding in all investigate…
Kontaktlēcu pielietojums redzes asuma uzlabošanai pacientiem ar anizometropijas ambliopiju
2017
Bakalaura darbs ir uzrakstīts angļu valodā uz 25 lapaspusēm. Tas satur 9 attēlus, 1 tabulu, 21 atsauci uz literatūras avotiem. Darba uzdevums ir novērtēt, vai kontaktlēcu lietošana pozitīvi ietekmē redzes funkcijas anizometropijas ambliopijas gadījumā. Pētījumā piedalījās 16 pacienti (24 – 54 g.v.). Pēc pilnas refrakcijas korekcijas izrakstīšanas katru mēnesi 6 mēnešu laikā tika novērtēts lēcas novietojums, iespējamās lēcas ģeometrijas, redzes asuma un binokularitātes izmaiņas. Visiem pacientiem uzlabojās redzes asums (0,4 ± 0,2, decimālās vienībās), novēroja pirmās pakāpes binokularitātes pazīmes un 11 pacientiem varēja noteikt rupju stereoredzi. Iegūtie rezultāti demonstrē, ka kontaktlēcu…
The Putative Metal Coordination Motif in the Endonuclease Domain of Human Parvovirus B19 NS1 Is Critical for NS1 Induced S Phase Arrest and DNA Damage
2011
The non-structural proteins (NS) of the parvovirus family are highly conserved multi-functional molecules that have been extensively characterized and shown to be integral to viral replication. Along with NTP-dependent helicase activity, these proteins carry within their sequences domains that allow them to bind DNA and act as nucleases in order to resolve the concatameric intermediates developed during viral replication. The parvovirus B19 NS1 protein contains sequence domains highly similar to those previously implicated in the above-described functions of NS proteins from adeno-associated virus (AAV), minute virus of mice (MVM) and other non-human parvoviruses. Previous studies have show…
Towards low-energy-light-driven bistable photoswitches : ortho-fluoroaminoazobenzenes
2021
AbstractThermally stable photoswitches that are driven with low-energy light are rare, yet crucial for extending the applicability of photoresponsive molecules and materials towards, e.g., living systems. Combined ortho-fluorination and -amination couples high visible light absorptivity of o-aminoazobenzenes with the extraordinary bistability of o-fluoroazobenzenes. Herein, we report a library of easily accessible o-aminofluoroazobenzenes and establish structure–property relationships regarding spectral qualities, visible light isomerization efficiency and thermal stability of the cis-isomer with respect to the degree of o-substitution and choice of amino substituent. We rationalize the exp…
Design, Construction, and Characterization of a New Regioisomer and Diastereomer Material Based on the Spirooxindole Scaffold Incorporating a Sulphon…
2020
The 1,3-dipolar cycloaddition reaction is one of the most rapid, and efficient protocols to access, and construct highly divergent heterocycle chiral auxiliaries. Free catalyst synthesis of spirooxindole scaffold incorporating sulphone moiety via one pot&ndash
De la perception sensorielle à la consommation du vin. Partie 1/2 : Mécanisme de la perception sensorielle : reflet de la réalité
2010
National audience; Afin de percevoir son environnement et de pouvoir réagir en conséquence, l’être humain est équipé de capteurs sensoriels. Ces capteurs constituent une interface entre le sujet et le monde extérieur et quelle que soit la stimulation extérieure, ils mettent en jeu les mêmes mécanismes sensoriels. Lorsque les capteurs sensoriels rentrent en contact avec un stimulus, les informations engendrées sont amplifiées, puis transmises au système nerveux central sous forme de signaux électriques (Mac Leod et Sauvageot, 1986) après avoir été progressivement filtrées, réduites et stabilisées. Ces informations électriques sont caractérisées d’une part par une masse globale d’activité, co…