Search results for "Specificity."

showing 10 items of 2232 documents

Quaternary diversification in European alpine plants: pattern and process

2004

Molecular clock approaches applied previously to European alpine plants suggest that Primula sect. Auricula , Gentiana sect. Ciminalis and Soldanella diversified at the beginning of the Quaternary or well within this period, whereas Globularia had already started diversifying in the (Late–)Tertiary. In the first part of this paper we present evidence that, in contrast to Globularia and Soldanella , the branching patterns of the molecular internal transcribed spacer phylogenies of both Primula and Gentiana are incompatible with a constant–rates birth–death model. In both of these last two taxa, speciation probably decreased through Quaternary times, perhaps because of some niche–filling pro…

Time FactorsExtinctionGeographyModels GeneticbiologyRange (biology)EcologyGenetic VariationSequence Analysis DNAPlantsbiology.organism_classificationGeneral Biochemistry Genetics and Molecular BiologySoldanellaEuropeEvolution MolecularGlobulariaPrimulaSpecies SpecificityRegression AnalysisGlacial periodGeneral Agricultural and Biological SciencesQuaternaryMolecular clockResearch ArticlePhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences
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Introduction to coronary imaging with 64-slice computed tomography

2005

The aim of this article is to illustrate the main technical improvements in the last generation of 64-row CT scanners and the possible applications in coronary angiography. In particular, we describe the new physical components (X-ray tube-detectors system) and the general scan and reconstruction parameters. We then define the scan protocols for coronary angiography with the new generation of 64-row CT scanners to enable radiologists to perform a CT study on the basis of the diagnostic possibilities.

Time FactorsImaging Sensitivity and Specificity Stents Time Factors TomographyContrast MediaSensitivity and Specificity64-row CTElectrocardiographyHeart RateSpiral Computed TomographyImage Processing Computer-AssistedHumanstechnical improvementsCoronary Artery BypassPhantoms ImagingPatient SelectionAlgorithms Artifacts Contrast Media Coronary Angiography/instrumentation/*methods Coronary Artery Bypass Coronary Stenosis/*radiography Electrocardiography Heart Rate Humans Image Processing; Computer-Assisted Patient Selection Phantoms; Imaging Sensitivity and Specificity Stents Time Factors Tomography; Spiral Computed Tomography; X-Ray Computed/instrumentation/*methodsCoronary StenosisComputer-Assisted Patient Selection PhantomsX-Ray Computed/instrumentation/*methodstechnical improvements; 64-row CT; coronary angiographyComputer-Assisted Patient Selection PhantomStentsAlgorithms Artifacts Contrast Media Coronary Angiography/instrumentation/*methods Coronary Artery Bypass Coronary Stenosis/*radiography Electrocardiography Heart Rate Humans Image Processingcoronary angiographyArtifactsTomography X-Ray ComputedTomography Spiral ComputedAlgorithms
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Host specificity of Argulus coregoni (Crustacea: Branchiura) increases at maturation.

2007

SUMMARYWe tested the hypothesis that host specificity in ectoparasites does not depend exclusively on the features of the host but also on surrounding habitats, using 2 fish ectoparasites, Argulus coregoni and A. foliaceus (Crustacea: Branchiura), occurring sympatrically in Finnish lakes. Although these parasites are considered to be of low specificity, we found that the larger of the 2 species, A. coregoni developed a pronounced preference for salmonid hosts at the beginning of maturation (defined by the presence of copulating specimens). Argulus foliaceus infects a much wider range of fish hosts. We showed that specialization of A. coregoni on salmonids does not necessarily result from in…

Time FactorsOntogenyPopulationCyprinidaeEctoparasitic InfestationsHost-Parasite InteractionsFish DiseasesSpecies SpecificityParasite hostingAnimalseducationFinlandLightingeducation.field_of_studybiologyEcologyBranchiurabiology.organism_classificationCrustaceanArgulus foliaceusOxygenInfectious DiseasesHabitatArguloidaOncorhynchus mykissAnimal Science and ZoologyParasitologyRainbow troutParasitology
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Metabolism of propafenone and verapamil by cryopreserved human, rat, mouse and dog hepatocytes: comparison with metabolism in vivo

2003

In the present study we examined the metabolism of [(14)C]propafenone (P) and [(14)C]verapamil (V) using cryopreserved human, dog (Beagle), rat (Sprague-Dawley) and mouse (NMRI) hepatocytes. The percentage ratios of the metabolites were identified after extraction by HPLC with UV and radioactivity detection. Phase-II metabolites were cleaved using beta-glucuronidase. Metabolism of the drugs by cryopreserved hepatocytes was compared with that in the respective species in vivo. All phase-I and -II metabolites known from in vivo experiments: 5-hydroxy-P (5-OH-P); 4'-hydroxy-P (4'-OH-P); N-despropyl-P (NdesP) and the respective glucuronides, were identified after incubation with cryopreserved h…

Time FactorsPropafenoneIn Vitro TechniquesPharmacologyCryopreservationRats Sprague-DawleyHydroxylationMicechemistry.chemical_compoundDogsGlucuronidesPropafenoneSpecies SpecificityIn vivomedicineAnimalsHumansIncubationAgedCryopreservationPharmacologyChemistryGeneral MedicineMetabolismMiddle AgedIn vitroRatsVerapamilBiochemistryHepatocytesVerapamilAnti-Arrhythmia Agentsmedicine.drugNaunyn-Schmiedeberg's Archives of Pharmacology
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Phylogenetic analysis of the isopenicillin-N-synthetase horizontal gene transfer.

1996

A phylogenetic study of the isopenicillin-N-synthetase (IPNS) gene sequence from prokaryotic and lower eukaryotic producers of beta-lactam antibiotics by means of a maximum-likelihood approach has been carried out. After performing an extensive search, rather than invoking a global molecular clock, the results obtained are best explained by a model with three rates of evolution. Grouped in decreasing order, these correspond to A. nidulans and then to the rest of the eukaryotes and prokaryotes, respectively. The estimated branching date between prokaryotic and fungal IPNS sequences (852 +/- 106 MY) strongly supports the hypothesis that the IPNS gene was horizontally transferred from bacteria…

Time FactorsSequence alignmentGram-Positive BacteriaAspergillus nidulansFungal ProteinsTransformation GeneticBacterial ProteinsSpecies SpecificityPhylogeneticsAspergillus nidulansBotanyGram-Negative BacteriaGeneticsMolecular clockMolecular BiologyGeneEcology Evolution Behavior and SystematicsPhylogenyGeneticsFungal proteinLikelihood FunctionsbiologyPhylogenetic treeModels GeneticRNA Ribosomal 5SRNA Fungalbiology.organism_classificationRNA BacterialHorizontal gene transferOxidoreductasesSequence AlignmentJournal of molecular evolution
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Enzymatic, physicochemical, nutritional and phytochemical profile changes of apple (Golden Delicious L.) juice under supercritical carbon dioxide and…

2018

The impact of supercritical carbon dioxide (SCCD) (10-60 MPa/45 °C/30 min) and subsequent 10 weeks storage at 4 °C on polyphenol oxidase (PPO), peroxidase (POD) activities, phenolic profile, vitamin C, sugars, physicochemical properties of cloudy apple juices was investigated. No significant changes in sugars and total polyphenols were observed, whereas significant degradation (≈28%) of vitamin C and individual polyphenols (≈18%) was noted after SCCD treatment. After 4 weeks storage only 34% of vitamin C was retained and no vitamin C was detected after this time. Ten weeks of storage caused hydrolysis of sucrose in 15%, whereas degradation of individual polyphenols ranged from 43 to 50% dep…

Time FactorsSucroseFood HandlingPhytochemicalsColorStorageCold storageAscorbic AcidPolyphenol oxidaseSubstrate SpecificityAnalytical Chemistrychemistry.chemical_compoundSupercritical carbon dioxide0404 agricultural biotechnologyPhenolsChlorogenic acidEnzyme activityVitamin CFood scienceCatechol oxidaseChromatography High Pressure LiquidColor; Enzyme activity; Polyphenols; Storage; Supercritical carbon dioxide; Synergistic effect; Vitamin C; Analytical Chemistry; Food ScienceVitamin CbiologyChemistryPolyphenolsfood and beverages04 agricultural and veterinary sciencesGeneral MedicineCarbon DioxideAscorbic acid040401 food scienceCold TemperatureFruit and Vegetable JuicesPeroxidasesPolyphenolMalusSynergistic effectbiology.proteinNutritive ValueCatechol OxidaseFood ScienceFood Chemistry
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Intraspecific diversity of Lactobacillus curvatus, Lactobacillus plantarum, Lactobacillus sakei, and Leuconostoc mesenteroides associated with vacuum…

2006

The intraspecific diversity of Leuconostoc mesenteroides, Lactobacillus curvatus, Lactobacillus sakei, and Lactobacillus plantarum was analyzed by randomly amplified polymorphic DNA (RAPD) PCR with universal primers M13 and T3. The study included 100 reference strains and 210 isolates recovered from two vacuum-packed Spanish meat products, fiambre de magro adobado and morcilla, previously identified by rDNA-restriction fragment length polymorphism profiles. The RAPD-M13 profiles identified isolates at species level in L. plantarum and L. mesenteroides, while RAPD-T3 provided profiles in L. sakei. The combination of RAPD-M13 and RAPD-T3 fingerprints revealed a total of 17 profiles in L. mese…

Time FactorsVacuumFood spoilageFood ContaminationMicrobiologyMicrobiologylaw.inventionSpecies SpecificitylawFood Preservationparasitic diseasesAnimalsHumansPhylogenyPolymerase chain reactionbiologyFood Packagingfood and beveragesLactobacillaceaebiology.organism_classificationRandom Amplified Polymorphic DNA TechniqueLactobacillus sakeiRAPDMeat ProductsLactobacillusConsumer Product SafetyLeuconostoc mesenteroidesLeuconostocLactobacillus plantarumBacteriaLactobacillus plantarumFood Science
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Fermentation profiles of Manzanilla-Aloreña cracked green table olives in different chloride salt mixtures.

2010

NaCl plays an important role in table olive processing affecting the flavour and microbiological stability of the final product. However, consumers demand foods low in sodium, which makes necessary to decrease levels of this mineral in fruits. In this work, the effects of diverse mixtures of NaCl, CaCl2 and KCl on the fermentation profiles of cracked directly brined Manzanilla-Aloreña olives, were studied by means of response surface methodology based in a simplex lattice mixture design with constrains. All salt combinations led to lactic acid processes. The growth of Enterobacteriaceae populations was always limited and partially inhibited by the presence of CaCl2. Only time to reach half …

Time FactorsWater activityFood HandlingTable oliveSodium chlorideSodiumPopulationMicroorganismsColony Count Microbialchemistry.chemical_elementBacterial growthSodium ChlorideMicrobiologyFermentation profileCalcium chloridePotassium Chloridechemistry.chemical_compoundCalcium ChlorideBriningEnterobacteriaceaeSpecies SpecificityFood PreservationOleaYeastsFood scienceeducationeducation.field_of_studyDose-Response Relationship DrugWaterHydrogen-Ion ConcentrationYeastLactic acidKineticschemistryBiochemistryPotassium chlorideTasteFermentationFood MicrobiologyFermentationSaltsFood ScienceFood microbiology
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Detection and identification Fabavirus species by one-step RT-PCR and multiplex RT-PCR

2014

The genus Fabavirus of the family Secoviridae comprises a group of poorly characterized viruses. To date, only five species have been described: Broad bean wilt virus 1 (BBWV-1), Broad bean wilt virus 2 (BBWV-2), Lamium mild mosaic virus (LMMV), Gentian mosaic virus (GeMV) and Cucurbit mild mosaic virus (CuMMV). The development is described of two RT-PCR procedures for the detection and identification of Fabavirus species: a one-step RT-PCR using a single pair of conserved primers for the detection of all fabaviruses, and a one-step multiplex RT-PCR using species-specific primers for the simultaneous detection and identification of the above-mentioned species of the genus Fabavirus. These m…

Time FactorsbiologyReverse Transcriptase Polymerase Chain ReactionBBWV-1 BBWV-2 GeMV CuMMV LMMV detection diagnosis multiplex RT-PCR conserved primersLamium mild mosaic virusSettore AGR/12 - Patologia VegetaleDetection Diagnosis Conserved primersbiology.organism_classificationSensitivity and SpecificityVirologyFabavirusBroad bean wilt virusReal-time polymerase chain reactionGenusVirologyPlant virusSecoviridaeRNA ViralIdentification (biology)MultiplexDNA PrimersPlant Diseases
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A thin layer-based amperometric enzyme immunoassay for the rapid and sensitive diagnosis of respiratory syncytial virus infections

2012

Abstract A simple electrochemical sandwich immunoassay involving a polystyrene microarray slide coated with monoclonal capture antibodies and carbon screen-printed sensors (SPS) was designed for the rapid diagnosis of respiratory syncytial virus (RSV). The detection of the antibody-antigen complex formation relied on the use of a horseradish peroxidase conjugate. Its chronoamperometric measurement detection was performed by confining a droplet of H 2 O 2 /3,3',5,5'-tetramethylbenzidine enzyme substrate/mediator solution within a thin layer between one spot of the microarray and the surface of one screen-printed electrochemical cell. The accumulation of the enzyme product in the thin film of…

Time Factorsrespiratory syncytial virus[SDV]Life Sciences [q-bio]Biosensing TechniquesRespiratory Syncytial Virus Infectionsscreen-printed sensorSensitivity and SpecificityHorseradish peroxidaseVirusAnalytical ChemistryImmunoenzyme TechniquesElectrochemistrymedicineHumans[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyimmunoassayAntigens ViralHorseradish PeroxidaseChromatographybiologymedicine.diagnostic_testChemistryAntibodies MonoclonalRespiratory infectionSubstrate (chemistry)Molecular biologyAmperometryRespiratory Syncytial VirusesHRP labelImmunoassay[SDE]Environmental Sciencesbiology.proteinColorimetrythin layer amperometric detectionAntibodyConjugate
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