Search results for "Sperm injection"
showing 10 items of 87 documents
A high oocyte yield for intracytoplasmic sperm injection treatment is associated with an increased chromosome error rate.
2009
Objective To compare the chromosome error rate among oocytes from stimulated ovaries after retrieval of 1–5 oocytes, 6–10 oocytes, and >10 oocytes. Design Retrospective cohort study. Setting A university-based human genetic institute in collaboration with a private fertility center. Patient(s) Nine hundred thirty-three women undergoing intracytoplasmic sperm injection (ICSI) with a poor prognosis. Intervention(s) Oocyte collection with ovarian stimulation. Polar body testing of ICSI oocytes for common chromosome errors. Main Outcome Measure(s) Chromosome error rate in oocytes, as determined by five-color fluorescence in situ hybridization. Result(s) In women less than 35 years and women bet…
Is the nuclear status of an embryo an independent factor to predict its ability to develop to term?
2012
Objective To determine the prognostic impact of the embryo nuclear status at day 2 among other major morphologic parameters (first cleavage at day 1, number of blastomeres and anuclear fragmentation at day 2) on the birth rate. Design Retrospective study. Setting Hospital IVF department. Patient(s) Women undergoing 1,629 day 2 transfers of 2,732 embryos from May 2006 to November 2008. Intervention(s) Four groups according to the embryo nuclear status. Main Outcome Measure(s) Implantation, miscarriage, and birth rates. Result(s) Univariate analysis indicated significantly higher birth rates when all blastomeres were mononucleated (15.0%) compared with embryos with not all blastomeres mononuc…
Assisted reproductive technology results: Why are live-birth percentages so low?
2014
The present bioessay aims to analyze the impact of parental age, cause of infertility, embryo chromosomal anomalies, assisted reproduction technology (ART) treatments, and environmental and occupational exposures to xenobiotics on ART results, particularly on live-birth percentages per transfer. Special attention is paid to analyzing the effects of these factors on the mitochondrial, genetic, and epigenetic traits of gametes and embryos to ascertain the molecular/cellular mechanisms responsible for the relatively low percentages of live births reported year after year in ART cycles. The bias of age distribution of women attending fertility clinics toward the late thirties and beyond and the…
Intracytoplasmic Testicular Sperm Injection: An Effective Treatment for Otherwise Intractable Obstructive Azoospermia
1995
AbstractPurpose: We evaluated the efficacy of intracytoplasmic sperm injection with testicular spermatozoa.Materials and Methods: Intracytoplasmic sperm injection was performed with spermatozoa obtained from testicular biopsy specimens in 15 patients with obstructive azoospermia, in whom standard microsurgical procedures were not feasible or had previously failed.Results: Fertilization was achieved in 14 to 15 cycles. Mean fertilization rate per cycle was 63.6 percent. Four clinical pregnancies occurred, for a pregnancy rate of 26.7 percent per started cycle and 28.6 percent per transfer.Conclusions: Intracytoplasmic testicular sperm injection is followed by high fertilization rates, and of…
Monozygote, weibliche Zwillingsfrühgeborene diskordant für das seltene, schwere Fehlbildungssyndrom einer fetalen Megazystis mit Kloakenfehlbildung n…
2016
Monozygote Zwillinge gelten gemeinhin als „identische Klone“. Es gibt jedoch eine zunehmende Anzahl an Fallberichten uber diskordante eineiige Zwillinge und Ursachen fur Diskordanz werden vermehrt untersucht. Wir berichten uber monozygote Zwillingsfruhgeborene, diskordant fur die seltene fetale Megazystis bei Kloakenfehlbildung. Durch Konzeption mittels intrazytoplasmatischer Spermieninjektion entstand nach Transfer von 2 Embryonen ein monochoriales, diamniales Zwillingspaar. Im ersten Trimenon wurde eine diskordante fetale Megazystis mit konsekutivem Oligohydramnion und Lungenhypoplasie bei unauffalligem Karyotyp diagnostiziert. Das betroffene Kind wurde bei 25+3 SSW geboren, palliativ beh…
Características de los recién nacidos tras fecundación in vitro
2009
Resumen: Objetivo: determinar en una unidad neonatal de nivel II la frecuencia de nacimientos tras fecundación in vitro (FIV) incluyendo FIV-ICSI (intracytoplasmic sperm injection) y comparar sus características con los de fecundación natural (FN), según sean gemelares o únicos. Pacientes y método: estudio prospectivo mediante revisiones fetales desde la semana 12 de gestación tras FIV, al nacer y al año de vida. Del 1 de enero de 2004 al 31 de marzo de 2007 nacieron 7.008 recién nacidos (RN), 113 tras FIV y 6.895 por FN. Resultados: la gemelaridad es del 2,4% en FN y el 56,6% en FIV (p<0,001). La edad materna media en únicos es 28±9 años en FN y 36±4 en FIV (p<0,05); en gemelares es 29±10 …
Are attachment dimensions associated with infertility-related stress in couples undergoing their first IVF treatment? A study on the individual and c…
2012
study question: Are attachment anxiety and avoidance dimensions in female and male partners in couples seeking infertility treat- ment associated with her and his infertility-related stress? summary answer: Attachment dimensions are significantly associated with several aspects of infertility stress in couples undergoing IVF treatment. what is known and what this paper adds: Attachment dimensions of anxiety and avoidance (where highly anxious individuals fear rejection and are preoccupied with maintaining proximity to their partner and highly avoidant individuals are uncomfortable with intimacy and prefer to maintain distance from their partner) may influence the well being of individuals u…
Sperm cryopreservation in oncological patients: a 14-year follow-up study.
2006
Objective Oncologic treatments can destroy spermatogenic dividing cells and cause azoospermia which could be irreversible. Sperm banking is the best option to preserve male fertility after these treatments. It is easy, inexpensive, and safe. To date, few clinical data are available about large series of cancer patients. Our objective was to determine the usefulness of these preventive sperm freezing protocols. Design Prospective study. Setting University-affiliated private fertility center. Patient(s) One hundred eighty-six cancer patients who banked sperm samples at our center before surgery or chemo- or radiotherapy treatments from 1991 to 2004. Intervention(s) Conjugal status, age, type …
Cumulative live-birth rates per total number of embryos needed to reach newborn in consecutive in vitro fertilization (IVF) cycles: a new approach to…
2011
Objective To report the use of cumulative live-birth rates (CLBRs) per ovarian stimulation cycle to measure the success of IVF is proving to be the most accurate method for advising couples who failed to conceive, although the accuracy yielded is relatively low, and cycle outcome is highly dependent on the number of embryos replaced. Our aim with this work is to report the CLBRs of IVF as a function of the number of embryos required to reach a live birth (EmbR), considering age, day of ET, and infertility etiology. Design Survival curves and Kaplan-Meier methods to analyze CLBR in a retrospective cohort with respect to the number of EmbR. Setting University-affiliated infertility center. Pa…
Time-dependent O2 consumption patterns determined optimal time ranges for selecting viable human embryos.
2012
Objective To evaluate correlations between metabolic activity and implantation potential of transferred embryos in a study based on oxygen (O 2 ) consumption (OC) measurements, because O 2 uptake is directly related to the capacity of an embryo to produce energy via adenosine triphosphate. Design Retrospective cohort study. Setting Infertility institute. Patient(s) Five hundred seventy-five injected oocytes in 56 first oocyte donation cycles with embryo transfer on day 3. Intervention(s) None. Main Outcome Measure(s) We analyzed embryo destination viability and implantation depending on the embryo OC rate obtained from 47,741 measurements (up to 85 measurements per embryo, 2–3 measurements …