Search results for "Static"
showing 10 items of 1528 documents
Electrostatic phenomena in ion exchange membranes
1971
Abstract Specific and transport properties of a cation and an anion exchange membrane in Na + and Cl - form respectively have been measured in water and dioxane water mixtures. A greater electrolyte absorption and a lesser specific conductivity and counterion transport number in solvents at higher dioxane content indicate strong electrostatic interactions between fixed groups in the membrane and counterions.
Investigation of insulin resistance in narcoleptic patients: dependent or independent of body mass index?
2011
Alice Engel1,2, Jana Helfrich1, Nina Manderscheid1, Petra B Musholt3, Thomas Forst3, Andreas Pfützner3, Norbert Dahmen1,21Department of Psychiatry, University of Mainz, Germany; 2Fachklinik Katzenelnbogen, Katzenelnbogen, Germany; 3IKFE, Institute for Clinical Research and Development, Mainz, GermanyBackground: Narcolepsy is a severe sleep-wake cycle disorder resulting in most cases from a lack of orexin, the energy balance-regulating hormone. Narcoleptic patients have been reported to suffer from an excess morbidity of Type 2 diabetes, even after correction for their often elevated body mass index.Methods: To explore whether narcolepsy is specifically associated with a propensity …
Ārstēšanas aspekti bērnu vecuma pacientiem ar zarnu invagināciju
2016
Problēmas būtība. Zarnu invaginācija ir visbiežākais zarnu obstrukcijas iemesls bērniem vecumā no trīs mēnešiem līdz trīs gadiem (Bode, 2008). Neskatoties uz zinātnisko publikāciju klāstu, kas veltīts zarnu invagināciju izpētei, joprojām nav vienotu rekomendāciju par ārstēšanas pielietošanu. Pētījuma mērķi. 1) Literatūras apskates analīze. 2) Analizēt BKUS diagnostikas un ārstēšanas taktiku (rezultātus) pacientiem ar zarnu invagināciju laika posmā no 2006. gada janvāra līdz 2015. gada decembrim. 3) Salīdzināt iegūtos rezultātus ar pasaules literatūras datiem. Darba metode. Pēdējo piecu gadu literatūras atlase, izmantojot medicīnas literatūras datubāzes pēc atslēgas vārdiem. Retrospektīvs pē…
Bovine herpesvirus 4-based vector delivering the full length xCT DNA efficiently protects mice from mammary cancer metastases by targeting cancer ste…
2018
Despite marked advancements in its treatment, breast cancer is still the second leading cause of cancer death in women, due to relapses and distal metastases. Breast cancer stem cells (CSCs), are a cellular reservoir for recurrence, metastatic evolution and disease progression, making the development of novel therapeutics that target CSCs, and thereby inhibit metastases, an urgent need. We have previously demonstrated that the cystine-glutamate antiporter xCT (SLC7A11), a protein that was shown to be overexpressed in mammary CSCs and that plays a key role in the maintenance of their redox balance, self-renewal and resistance to chemotherapy, is a potential target for mammary cancer immunoth…
Blockade of MIF–CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma
2018
Mounting an effective immune response against cancer requires the activation of innate and adaptive immune cells. Metastatic melanoma is the most aggressive form of skin cancer. While immunotherapies have shown a remarkable success in melanoma treatment, patients develop resistance by mechanisms that include the establishment of an immune suppressive tumor microenvironment. Thus, understanding how metastatic melanoma cells suppress the immune system is vital to develop effective immunotherapies against this disease. In this study, we find that macrophages (MOs) and dendritic cells (DCs) are suppressed in metastatic melanoma and that the Ig-CDR-based peptide C36L1 is able to restore MOs and …
European citizenship : opportunities and abuses in private international family law
2021
El ensayo se centra en el papel de la autonomía jurídica en la regulación del estado familiar y las relaciones familiares entre los miembros de la unidad familiar típica o atípica. De hecho, el papel de la autonomía jurídica también ha sido ampliado con la ciudadanía europea, entendida por el Tribunal de Justicia de la Unión Europea como una fuente autónoma de derechos. Esta ciudadanía, que se suma a la nacional, ha permitido a la pareja ?estática?, aún en ausencia del carácter transnacional de la situación familiar, elegir la ley y los instrumentos de los ordenamientos jurídicos extranjeros a aplicar al ámbito patrimonial y a las relaciones existenciales de la comunidad de vida. El ensayo …
On the limit velocity and buckling phenomena of axially moving orthotropic membranes and plates
2011
In this paper, we consider the static stability problems of axially moving orthotropic membranes and plates. The study is motivated by paper production processes, as paper has a fiber structure which can be described as orthotropic on the macroscopic level. The moving web is modeled as an axially moving orthotropic plate. The original dynamic plate problem is reduced to a two-dimensional spectral problem for static stability analysis, and solved using analytical techniques. As a result, the minimal eigenvalue and the corresponding buckling mode are found. It is observed that the buckling mode has a shape localized in the regions close to the free boundaries. The localization effect is demon…
Solvability of a first order system in three-dimensional non-smooth domains
1985
summary:A system of first order partial differential equations is studied which is defined by the divergence and rotation operators in a bounded nonsmooth domain $\Omega\subset \bold R^3$. On the boundary $\delta\Omega$, the vanishing normal component is prescribed. A variational formulation is given and its solvability is investigated.