Search results for "Subgroup"

showing 10 items of 237 documents

Frailty and Mortality Outcomes After Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis.

2017

Abstract Background Frailty has been identified as a risk factor for mortality. However, whether frailty increases mortality risk in patients undergoing percutaneous coronary intervention (PCI) has been controversial. Therefore, we conducted a systematic review and meta-analysis of the frailty measures and mortality outcomes in this setting. Methods PubMed and EMBASE were searched until July 23, 2017 for studies evaluating the association between frailty measures and mortality in individuals who have undergone PCI. Results A total of 141 entries were retrieved from our search strategy. A total of 8 studies involving 2332 patients were included in the final meta-analysis (mean age: 69 years;…

Malemedicine.medical_specialtymedicine.medical_treatmentSubgroup analysisCoronary Artery Disease030204 cardiovascular system & hematologyCoronary AngiographyRisk Assessment03 medical and health sciences0302 clinical medicinePercutaneous Coronary InterventionPredictive Value of TestsInternal medicineCause of DeathmedicineHumans030212 general & internal medicineRisk factorGeneral NursingAgedProportional Hazards ModelsFrailtybusiness.industryHealth PolicyMortality rateHazard ratioPercutaneous coronary interventionGeneral MedicineMiddle Agedmedicine.diseasePrognosisSurvival AnalysisConfidence intervalTreatment OutcomeMeta-analysisConventional PCIMultivariate AnalysisFemaleMedical emergencyGeriatrics and GerontologybusinessJournal of the American Medical Directors Association
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Recovery of Lower Extremity Performance After Hip Fracture Depends on Prefracture and Postdischarge Mobility : A Subgroup Analysis of a Randomized Re…

2016

Malemedicine.medical_specialtymedicine.medical_treatmentSubgroup analysisrehabilitation03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationActivities of Daily LivingmedicineHumans030212 general & internal medicineAgedRandomized Controlled Trials as TopicAged 80 and overHip fractureRehabilitationHip Fracturesbusiness.industryta3141Recovery of FunctionMiddle Agedmedicine.diseasemobilityhip fracturePhysical therapylower extremityFemaleGeriatrics and Gerontologybusiness030217 neurology & neurosurgeryperformanceJournal of the American Geriatrics Society
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Intracerebral Hemorrhage and Outcome After Thrombolysis in Stroke Patients Using Selective Serotonin-Reuptake Inhibitors.

2017

Background and Purpose— Selective serotonin-reuptake inhibitors (SSRIs) impair platelet function and have been linked to a higher risk of spontaneous intracerebral hemorrhage—an association that may be augmented by oral anticoagulants (OAC). We aimed to assess whether preadmission treatment with SSRIs in patients with acute ischemic stroke is associated with post-thrombolysis symptomatic intracerebral hemorrhage (sICH) and functional outcome. Methods— A multicenter retrospective analysis was conducted in prospective registries of patients treated by thrombolysis within 4.5 hours of stroke onset. The association between preadmission treatment with SSRIs and sICH (ECASS II definition [Europe…

Malemedicine.medical_specialtytherapeutic use [Anticoagulants]medicine.medical_treatmentSubgroup analysisepidemiology [Cerebral Hemorrhage]Risk AssessmentCohort Studies03 medical and health sciencesadverse effects [Serotonin Uptake Inhibitors]0302 clinical medicineModified Rankin ScaleInternal medicinemedicineHumansThrombolytic Therapy030212 general & internal medicineddc:610610 Medicine & healthStrokeCerebral HemorrhageAgedRetrospective StudiesAdvanced and Specialized NursingIntracerebral hemorrhageAged 80 and overtherapy [Cerebral Hemorrhage]business.industryAnticoagulantsThrombolysisOdds ratioMiddle Agedmedicine.diseaseadverse effects [Selective Serotonin Reuptake Inhibitors]Prognosisdrug therapy [Stroke]StrokeTreatment OutcomeAnesthesiaConcomitantSerotonin Uptake InhibitorsFemaleNeurology (clinical)Cardiology and Cardiovascular Medicinebusiness030217 neurology & neurosurgerySelective Serotonin Reuptake Inhibitorsepidemiology [Stroke]Cohort study
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Bloodstream Infections in Hospitalized Patients with COVID-19: A Systematic Review and Meta-Analysis

2021

Background: Little is known about the occurrence of bloodstream infections in hospitalized patients with COVID-19 and the related clinical consequences. The aim of this systematic review and meta-analysis was to estimate the pooled occurrence of BSIs among hospitalized patients with COVID-19 and mortality of this patient population. Methods: A systematic search was performed on PubMed, EMBASE, and Web of Science from inception to 19 April 2021. The primary outcome was the occurrence of BSIs among hospitalized patients with COVID-19. The secondary outcome was mortality at the longest available follow-up. Results: Forty-six studies met the inclusion criteria, with a total of 42,694 patients e…

Microbiology (medical)medicine.medical_specialtyCoronavirus disease 2019 (COVID-19)bloodstream infectionsbusiness.industryHospitalized patientsQH301-705.5Mortality ratereviewCOVID-19Subgroup analysisMicrobiologyArticlePrimary outcomeVirologyInternal medicineMeta-analysisMedicineIn patientBiology (General)businessSystematic searchMicroorganisms
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Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

2015

G.B. and S.N. acknowledge funding support for this work from the National Institute for Health Research (NIHR) Mental Health Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London. P.H.L. is supported by US National Institute of Mental Health (NIMH) grant K99MH101367. Genome-wide association studies (GWAS) of psychiatric disorders have identified multiple genetic associations with such disorders, but better methods are needed to derive the underlying biological mechanisms that these signals indicate. We sought to identify biological pathways in GWAS data from over 60,000 participants from the Psychiatric Genomics Consortium. We developed an an…

Netherlands Twin Register (NTR)Statistical methodsAutismMedizinLOCIGenome-wide association studyheritabilityGenome-wide association studiesHistonesGenètica mèdica0302 clinical medicineHistone methylationDatabases Genetic2.1 Biological and endogenous factorsPsychologyGWASAetiologyPsychiatric geneticsR2Cbipolar disorderPsychiatry0303 health sciencesDisordersLociDepressionGeneral NeuroscienceMental DisordersMedical geneticsMETHYLATIONBrain3rd-DASSerious Mental IllnessPsychiatric Disorders3. Good healthHistoneMental HealthSchizophreniaMental DisorderCognitive Sciences[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]PromotersBDCBURDENRC0321 Neuroscience. Biological psychiatry. NeuropsychiatryHumanSignal Transductionmedicine.medical_specialtyDISORDERSGenomicsNetwork and Pathway Analysis Subgroup of Psychiatric Genomics ConsortiumBurdenBiologyMethylationArticleBiological pathwayPROMOTERS03 medical and health sciencesDatabasesGeneticmedicineGenetics/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_HumansGenetic Predisposition to Diseasehistone methylationBipolar disorderPsiquiatriaAUTISMPsychiatry030304 developmental biologyGenetic associationNeurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7]Neurology & NeurosurgeryNeuroscience (all)Human GenomeNeurosciencesmedicine.diseaseBrain DisordersGood Health and Well BeingDE-NOVO MUTATIONSPerturbações do Desenvolvimento Infantil e Saúde MentalRC0321SchizophreniaGenome-wide Association StudiesDe-novo mutationsmajor depressionNeuroscience030217 neurology & neurosurgeryGenome-Wide Association Study
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The Mutational Landscape of Acute Myeloid Leukaemia Predicts Responses and Outcomes in Elderly Patients from the PETHEMA-FLUGAZA Phase 3 Clinical Tri…

2021

This article belongs to the Collection The Biomarkers for the Diagnosis and Prognosis in Cancer.

Neuroblastoma RAS viral oncogene homologOncologyCancer Researchgenetic riskMyeloid neoplasialeukemic cells0302 clinical medicinecytarabineclinical trials and observations:Other subheadings::/diagnosis [Other subheadings]MedicineComplete remissionazacytidineolder adultsRC254-282variantsLeukemiaAzacytidineHazard ratioleukemiaVariantsCytarabineacute:Neoplasms::Neoplasms by Histologic Type::Leukemia::Leukemia Myeloid::Leukemia Myeloid Acute [DISEASES]Neoplasms. Tumors. Oncology. Including cancer and carcinogensMyeloid leukemiaFludarabineLeukemiaOncology030220 oncology & carcinogenesisNGSOlder adultsLeucèmia mieloide aguda - Tractamentmyeloid neoplasiaMyelocyticmedicine.drugmedicine.medical_specialtymyelocyticcomplete remission:Otros calificadores::/diagnóstico [Otros calificadores]Subgroup analysisLeukemic cellsAcutePrognostic factorsArticle:neoplasias::neoplasias por tipo histológico::leucemia::leucemia mieloide::leucemia mieloide aguda [ENFERMEDADES]03 medical and health sciencesInternal medicineGenetic riskbusiness.industryprognostic factors:diagnóstico::pronóstico::resultado del tratamiento [TÉCNICAS Y EQUIPOS ANALÍTICOS DIAGNÓSTICOS Y TERAPÉUTICOS]Odds ratio:Diagnosis::Prognosis::Treatment Outcome [ANALYTICAL DIAGNOSTIC AND THERAPEUTIC TECHNIQUES AND EQUIPMENT]medicine.diseaseAvaluació de resultats (Assistència sanitària)CytarabinebusinessClinical trials and observations030215 immunology
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Large characteristically simple sections of finite groups

2021

In this paper we prove that if G is a group for which there are k non-Frattini chief factors isomorphic to a characteristically simple group A, then G has a normal section C/R that is the direct product of k minimal normal subgroups of G/R isomorphic to A. This is a significant extension of the notion of crown for isomorphic chief factors.

Normal subgroupAlgebra and Number TheoryGroup (mathematics)Applied MathematicsExtension (predicate logic)Characteristically simple groupCombinatoricsComputational MathematicsSection (category theory)Simple (abstract algebra)Geometry and TopologyMatemàticaAnalysisDirect productMathematics
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Characterizations of Schunck Classes of Finite Soluble Groups

1998

All groups considered in this paper are finite and soluble.Characterization of Schunck classes and saturated formations by meansof certain embedding properties of their associated projectors plays animportant part in the Theory of Classes of Groups.Schunck classes whose projectors are normal subgroups were studied byBlessenohl and Gaschutz. They characterize these classes as the classes

Normal subgroupAlgebraAlgebra and Number TheoryEmbeddingMathematicsJournal of Algebra
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Permutable subnormal subgroups of finite groups

2009

The aim of this paper is to prove certain characterization theorems for groups in which permutability is a transitive relation, the so called PT -groups. In particular, it is shown that the finite solvable PT -groups, the finite solvable groups in which every subnormal subgroup of defect two is permutable, the finite solvable groups in which every normal subgroup is permutable sensitive, and the finite solvable groups in which conjugatepermutability and permutability coincide are all one and the same class. This follows from our main result which says that the finite modular p-groups, p a prime, are those p-groups in which every subnormal subgroup of defect two is permutable or, equivalentl…

Normal subgroupClass (set theory)PermutableMathematics::CombinatoricsGeneral MathematicsSubnormalModular p-groupGrups Teoria deCharacterization (mathematics)Prime (order theory)PT -groupSubnormal subgroupCombinatoricsMathematics::Group TheorySolvable groupPermutable primeÀlgebraAlgebra over a fieldMATEMATICA APLICADAMathematicsConjugate-Permutable
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Blocks Relative to a Normal Subgroup in π-Separable Groups

2000

Normal subgroupCombinatoricsAlgebra and Number TheoryMathematicsSeparable spaceJournal of Algebra
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