Search results for "Support"
showing 10 items of 2310 documents
Visualizing the flow of evidence in network meta-analysis and characterizing mixed treatment comparisons
2013
Network meta-analysis techniques allow for pooling evidence from different studies with only partially overlapping designs for getting a broader basis for decision support. The results are network-based effect estimates that take indirect evidence into account for all pairs of treatments. The results critically depend on homogeneity and consistency assumptions, which are sometimes difficult to investigate. To support such evaluation, we propose a display of the flow of evidence and introduce new measures that characterize the structure of a mixed treatment comparison. Specifically, a linear fixed effects model for network meta-analysis is considered, where the network estimates for two trea…
A Knowledge Management and Decision Support Model for Enterprises
2011
We propose a novel knowledge management system (KMS) for enterprises. Our system exploits two different approaches for knowledge representation and reasoning: a document-based approach based on data-driven creation of a semantic space and an ontology-based model. Furthermore, we provide an expert system capable of supporting the enterprise decisional processes and a semantic engine which performs intelligent search on the enterprise knowledge bases. The decision support process exploits the Bayesian networks model to improve business planning process when performed under uncertainty. Copyright © 2011 Patrizia Ribino et al.
Sparse kernel methods for high-dimensional survival data
2008
Abstract Sparse kernel methods like support vector machines (SVM) have been applied with great success to classification and (standard) regression settings. Existing support vector classification and regression techniques however are not suitable for partly censored survival data, which are typically analysed using Cox's proportional hazards model. As the partial likelihood of the proportional hazards model only depends on the covariates through inner products, it can be ‘kernelized’. The kernelized proportional hazards model however yields a solution that is dense, i.e. the solution depends on all observations. One of the key features of an SVM is that it yields a sparse solution, dependin…
Coupled variable selection for regression modeling of complex treatment patterns in a clinical cancer registry.
2013
For determining a manageable set of covariates potentially influential with respect to a time-to-event endpoint, Cox proportional hazards models can be combined with variable selection techniques, such as stepwise forward selection or backward elimination based on p-values, or regularized regression techniques such as component-wise boosting. Cox regression models have also been adapted for dealing with more complex event patterns, for example, for competing risks settings with separate, cause-specific hazard models for each event type, or for determining the prognostic effect pattern of a variable over different landmark times, with one conditional survival model for each landmark. Motivat…
A decision support system methodology for forecasting of time series based on soft computing
2006
Exponential procedures are widely used as forecasting techniques for inventory control and business planning. A number of modifications to the generalized exponential smoothing (Holt-Winters) approach to forecasting univariate time series is presented, which have been adapted into a tool for decision support systems. This methodology unifies the phases of estimation and model selection into just one optimization framework which permits the identification of robust solutions. This procedure may provide forecasts from different versions of exponential smoothing by fitting the updated formulas of Holt-Winters and selects the best method using a fuzzy multicriteria approach. The elements of the…
Diffusion and Migration
2003
The sections in this article are Introduction Fundamental Concepts Diffusion–migration Flux Equations Poisson Equation and the LEN Assumption Continuity Equation Ohm's Law and Migrational Transport Numbers Diffusion-conduction Flux Equation Diffusion Boundary Layer Faraday's Law and Integral Transport Numbers Nernst Equation and Concentration Overpotential Steady State Current–voltage Curves of Systems with One Active Species Integration of the Transport Equations Solutions of Homovalent Ions, |zi | =z Binary Electrolyte Solutions Ternary Electrolyte Solutions. The Supporting Electrolyte Weak Binary Electrolyte Steady State Current–overpotential Curves in the Presence of Supporting Electrol…
Adaptive sparse representation of continuous input for tsetlin machines based on stochastic searching on the line
2021
This paper introduces a novel approach to representing continuous inputs in Tsetlin Machines (TMs). Instead of using one Tsetlin Automaton (TA) for every unique threshold found when Booleanizing continuous input, we employ two Stochastic Searching on the Line (SSL) automata to learn discriminative lower and upper bounds. The two resulting Boolean features are adapted to the rest of the clause by equipping each clause with its own team of SSLs, which update the bounds during the learning process. Two standard TAs finally decide whether to include the resulting features as part of the clause. In this way, only four automata altogether represent one continuous feature (instead of potentially h…
Tools, Human Development and Mathematics
2016
This chapter raises a number of issues from pre-history and history that one mathematics educator considers ‘worthy of mention’ with regard to tools and mathematics. These issues are: tool use in the development of the human species (phylogenesis); tool use in a mathematical culture, ancient Greek mathematics that goes beyond the obvious tools; an example from ancient Indian mathematics that bears some resemblances to Jon’s experimental mathematics described in Chap. 3; the mutual support of hand, mind and artefact in expert use of an abacus; a consideration of a period (sixteenth-century Europe) where there was a rapid advance in the development of mathematical tools.
Information systems and strategy design
1999
Abstract Strategic thinking forms a wide-ranking, complex area of thought. It also seems to be an extremely interesting and important field in both management practice and literature. Recently, the areas that the different functions (like accounting, marketing, production and information systems) of firm and strategic thinking have in common have been lively discussed. In this paper, the applicability of information systems thinking to strategic thinking is outlined. For that purpose, three modes of strategy-making are explicated: strategy-making as management process, as game-playing and as leadership. In each of these three modes, the strategy design phase and especially the essentials of…
Flexible strategic planning of transport systems
2012
Abstract This paper presents a decision support methodology for long-range planning of transport systems that exhibits strategic flexibility and stochastic system parameters. Unlike one-off strategic decisions, flexible decisions should be dynamically reformulated with time. The proposed methodology is based on the construction of a tree structure of multiple interlinked tactical planning problems, each associated with a scenario in the tree, where problems under scenarios at intermediate dates incorporate in their formulation the solution of the corresponding problems associated with past (future) connected scenarios. The resulting tree structure of interconnected planning decisions become…