Search results for "T(reg)"
showing 10 items of 46 documents
"Saliamoci sopra e voliamo via..." Percorsi di Beni Montresor e Philip Glass verso "Le Streghe di Venezia" (1994-2009)
2016
Il saggio delinea i percorsi creativi di Philip Glass a partire dall'inizio dalla fine degli anni Sessanta, con particolare riferimento alle opere o spettacoli di teatro musicale. Nella seconda parte vengono descritti l'eperienza biografica e artistica di Beni Montresor, nonché la genesi e i caratteri musicali dell'opera in due atti "The Witches of Venice" (Le Streghe di Venezia, 1994-2009), presentata al Teatro Massimo di Palermo nella versione che include anche i testi di Vincenzo Cerami.
CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes
2013
CD39 is an ectoenzyme, present on different immune cell subsets, which mediates immunosuppressive functions catalyzing ATP degradation. It is not known whether CD39 is expressed and implicated in the activity of CD8+ regulatory T lymphocytes (Treg). In this study, CD39 expression and function was analyzed in both CD8+ and CD4+CD25hi Treg from the peripheral blood of healthy donors as well as from tumor specimens. CD39 was found expressed by both CD8+ (from the majority of healthy donors and tumor patients) and CD4+CD25 hi Treg, and CD39 expression correlated with suppression activity mediated by CD8+ Treg. Importantly, CD39 counteraction remarkably inhibited the suppression activity of CD8+…
Compensation. Garantie à première demande souscrite par une banque. Contre-garantie à première demande fournie par une autre banque. Débiteur garanti…
2001
International audience; (Com. 6 mars 2001, Gladel et Beauquis c/ Sté Générale)
Dissenys d'investigació en Psicologia (III). Lliuraments
2017
Ejercicios teóricos y prácticos para resolver en clase y para entregar.
Constructing Proletarian Nation(s): PSOE Internationalism in the Second Republic (1931–1932)
2023
Este artículo busca mejorar nuestra comprensión de la naturaleza del internacionalismo socialista, en particular considerando el lugar de la nación en su funcionamiento y esencia. Para ello, se utiliza el concepto de internacionalismo para estudiar el caso particular del Partido Socialista Obrero Español (PSOE) durante la Segunda República española. En el primer apartado, nos centramos en la reunión de la ejecutiva de la Federación Internacional de Sindicatos (IFTU) en Madrid en 1931, y las posteriores celebraciones del Primero de Mayo en la ciudad. En el segundo, analizamos el uso del internacionalismo por parte del PSOE en los debates sobre la descentralización del Estado republicano. Est…
L. Ciappetta, La zingara, l'erborista e lo schiavo. L'Inquisizione a Maiorca (1583-1625)
2011
Storia sociale su uno dei tribunali meno indagati dalla storia sull'Inquisizione. Particolare rilievo alla comunità maiorchina nei suoi addentellati con territorio, tradizioni e pratiche magiche.
Humanism and criticism in T. S. Eliot and Carles Riba
2021
T. S. Eliot i Carles Riba són dos autors amb moltes similituds: tots dos van viure aproximadament durant la mateixa època (la primera meitat del segle XX), tots dos van destacar com a poetes i com a crítics, i tots dos van escriure sobre temes literaris semblants, com, per exemple, l’humanisme, i sobre diversos autors de la literatura europea, com Dante, Goethe i Baudelaire. Però les seves diferents circumstàncies biogràfiques i els diferents contextos literaris, socials i polítics van condicionar la seva concepció de l’humanisme i la seva interpretació d’alguns dels principals escriptors de la cultura occidental. L’objectiu d’aquest article és fer un exercici de literatura comparada per …
Differential impact of high and low penetrance TNFRSF1A gene mutations on conventional and regulatory CD4+ T cell functions in TNFR1-associated perio…
2015
Abstract TNFR-associated periodic syndrome is an autoinflammatory disorder caused by autosomal-dominant mutations in TNFRSF1A, the gene encoding for TNFR superfamily 1A. The lack of knowledge in the field of TNFR-associated periodic syndrome biology is clear, particularly in the context of control of immune self-tolerance. We investigated how TNF-α/TNFR superfamily 1A signaling can affect T cell biology, focusing on conventional CD4+CD25− and regulatory CD4+CD25+ T cell functions in patients with TNFR-associated periodic syndrome carrying either high or low penetrance TNFRSF1A mutations. Specifically, we observed that in high penetrance TNFR-associated periodic syndrome, at the molecular le…
Vitamin D increases the production of IL-10 by regulatory T cells in patients with systemic sclerosis
2019
OBJECTIVES: Vitamin D status influences the risk to develop autoimmune diseases affecting the percentage and/or functions of regulatory T cells (Tregs). Since low levels of 25 (OH) D have been decreased in patients with systemic sclerosis (SSc), we aimed to study the effect of Vitamin D3 (cholecalciferol) supplementation on Tregs frequencies and functions. METHODS: Peripheral blood and sera samples were obtained from 45 SSc patients and controls (HC). A number of eighteen SSc patients had consumed Cholecalciferol (orally) at the dose of 25.000 UI/month for 6 months at the time of enrollment. 25(OH)D serum levels were measured and VDR polymorphisms, were genotyped by polymerase chain reactio…
A non-redundant role for OX40 in the competitive fitness of Treg in response to IL-2.
2010
OX40 stimulation is known to enhance activation of effector T cells and to inhibit induction and suppressive function of Treg. Here we uncovered a novel role of OX40 in sustaining Treg competitive fitness in vivo, during repopulation of lymphopenic hosts and reconstitution of BM chimeras. Defective expansion of OX40-null Treg diminished their ability to suppress inflammation in a model of lymphopenia-driven colitis. OX40-mediated promotion of Treg fitness spanned beyond lymphopenic environments, as endogenous Treg in OX40-null mice showed decreased accumulation during thymic development, enhanced susceptibility to antibody-mediated depletion and defective turnover following thymectomy. In v…