Search results for "T.I.C."
showing 10 items of 2328 documents
Phenotypic APC resistance as a marker of hypercoagulability in primitive cerebral lymphoma
2005
Thrombosis is the most frequent complication and the second cause of death in patients with malignant disease. Primary central nervous system non-Hodgkin's lymphoma represents a rare pathology. Resistance to APC is usually linked to a factor V (FV) gene mutation changing an Arg 506 to a Gln in the APC cleavage site.In our study, we aimed at investigating the presence of activated protein C resistance (APC-r) and other markers of hypercoagulability in 25 selected patients with a diagnosis of primitive cerebral lymphoma who had suffered from an ischemic episode of TIA and/or stroke.25 selected patients with a diagnosis of primitive cerebral lymphoma and 50 healthy subjects acted as control gr…
Effects of thrombin and of the phospholipase C inhibitor, D609, on the vascularity of the chick chorioallantoic membrane.
2000
Abstract Microvascular corrosion casting was used to assess the effects of thrombin and D609, a phospholipase C inhibitor, on the vascularity of the chick embryo chorioallantoic membrane (CAM). Discs containing vehicle, thrombin or D609 were placed on the CAM of fertilized white Leghorn eggs on Day 9 of gestation and vascularity was assessed on Day 11. Thrombin caused significant increases in the numbers (43%), diameters (5%) and lengths (17%), of both pre- and postcapillaries (first-order vessels by centripetal ordering). Conversely, D609 caused a decrease in the numbers (27%), lengths (12%) and diameters (8%) of first-order vessels. D609 decreased the total vascular volume of first- to th…
"A 304-year experiment which worked some but not all of the time" : Britain and British identities in three English, Scottish and Welsh newspapers in…
2014
Britannia ja sen eri maat ovat unionin pitkän historian kuluessa kohdanneet lukuisia muutoksia ja haasteita. Viimeaikaisimmat näistä haasteista ovat liittyneet esimerkiksi siihen miten unionia ja sen maita hallitaan: vuonna 1997 unionin valtaa hajautettiin sisäisille paikallishallinnoille, jonka jälkeen muun muassa Wales on saavuttanut laajemmat oikeudet omien lakien säätämiseen ja Skotlanti on syksyllä 2014 äänestämässä mahdollisesta itsenäisyydestä. Tällaiset kehitykset herättävät kysymyksiä siitä, miten unioni nykyään toimii, kuinka vahvasti sen eri maat ovat sidoksissa toisiinsa, ja miltä sen tulevaisuus näyttää. Tämän tutkielman tarkoitus on tarkastella sitä, miten Britanniaa ja britti…
Improving sensitivity in simultaneous determination of copper carboxylates by nonaqueous capillary electrophoresis
2005
Abstract A new method of nonaqueous capillary electrophoresis (NACE) with UV spectrophotometric detection was developed and optimized for the simultaneous determination of seven carboxylates (trans-1,2-diaminocyclohexane-N,N,N′,N′-tetraacetic acid (CDTA), diethylenetriaminepentaacetic acid (DTPA), ethylenediaminetetraacetic acid (EDTA), N-(2-hydroxyethyl)ethylenediamine-N,N′,N′-triacetic acid (HEDTA), nitrilotriacetic acid (NTA), 1,3-diaminopropane-N,N,N′,N′-tetraacetic acid (PDTA) and triethylenetetraaminehexaacetic acid (TTHA)) as copper complexes. The method development was carried out by using a fused silica capillary. Background electrolyte (BGE) was optimized and the best separation a…
Biosynthesis of Sinapigladioside, an Antifungal Isothiocyanate from Burkholderia Symbionts
2021
Abstract Sinapigladioside is a rare isothiocyanate‐bearing natural product from beetle‐associated bacteria (Burkholderia gladioli) that might protect beetle offspring against entomopathogenic fungi. The biosynthetic origin of sinapigladioside has been elusive, and little is known about bacterial isothiocyanate biosynthesis in general. On the basis of stable‐isotope labeling, bioinformatics, and mutagenesis, we identified the sinapigladioside biosynthesis gene cluster in the symbiont and found that an isonitrile synthase plays a key role in the biosynthetic pathway. Genome mining and network analyses indicate that related gene clusters are distributed across various bacterial phyla including…
Incidental catch of marine turtles by Spanish bottom trawlers in the western Mediterranean
2014
A questionnaire-based survey of fishermen was conducted in the Valencia region (eastern Spain) to assess the levels of marine turtle bycatch. Interviews covered 41.3% of the bottom trawling fleet in the region and included 111 fishermen (one per boat). Results were combined with those from previous studies conducted in neighbouring regions using the same methodology to assess the global impact of bottom trawling on the western Mediterranean stock of the loggerhead turtle (Caretta caretta). Estimated turtle catch per unit effort (CPUE) is 0.09 turtles per vessel per month, according to the information reported by fishermen. As a consequence, the whole fleet of bottom trawlers operating off t…
Bioactive compounds from mustard flours for the control of patulin production in wheat tortillas
2016
Abstract Patulin (PAT) is a toxic fungal metabolite produced by Penicillium, Aspergillus and Byssochlamys growing especially in fruit and cereals. PAT exhibits a number of toxic effects in animals and its presence in food is undesirable. In this study the reduction of the mycotoxin PAT produced by a strain of Penicillium expansum, on wheat tortillas was studied using volatile bioactive compounds present in the oriental and yellow mustard flour and also using the standard solution of the antifungal compound allyl isothiocyanate (AIT), developing an active packaging with two different systems of release of those bioactive compounds. Also the kinetic of volatilization of the compounds used in …
Theoretical study of a Bénard Marangoni problem
2011
[EN] In this paper we prove the existence of strong solutions for the stationary Benard-Marangoni problem in a finite domain flat on the top, bifurcating from the basic heat conductive state. The Benard-Marangoni problem is a physical phenomenon of thermal convection in which the effects of buoyancy and surface tension are taken into account. This problem is modelled with a system of partial differential equations of the type Navier-Stokes and heat equation. The boundary conditions include crossed boundary conditions involving tangential derivatives of the temperature and normal derivatives of the velocity field. To define tangential derivatives at the boundary, intended in the trace sense,…
Četrgadīgu bērnu pētniecisko prasmju pilnveide dabas zinību mācību jomas centrā
2021
Kvalifikācijas darbs: Četrgadīgu bērnu pētniecisko prasmju pilnveide dabas zinību mācību jomas centrā. Darba autore: Ivanda Balsa Darba zinātniskā vadītāja: profesore, Dr.paed. Maruta Sīle Pētījuma mērķis: Pētīt pētniecisko prasmju pilnveides iespējas dabas mācību jomas centrā četru gadu veciem bērniem. Pētījuma uzdevumi: 1.Analizēt zinātniskās teorijas par pētnieciskajām prasmēm, 2. Raksturot pētnieciskās prasmes četrgadīgiem bērniem, 3. Organizēt empīrisko pētījumu un pamatot metožu izvēli, 4. Analizēt empīriskā pētījuma iegūtos datus. Darba ietvaros tika organizēts un veikts empīriskais pētījums pirmsskolas izglītības iestādē “X” par pētniecisko prasmju pilnveides iespējām dabas zinību m…
Bērnu pozitīvu savstarpējo attiecību sekmēšanas iespējas dramatizācijas rotaļās
2018
Pētījuma mērķis: apkopojot zinātniskās atziņas, izpētīt 4-6 gadīgu bērnu savstarpējo sadarbību un saprašanos iesaistoties dramatizācijas rotaļās Darba saturs: 1. Sabiedrības savstarpējo attiecību vispārīgs raksturojums 2. Pirmsskolas (4-6g.) vecumsposma bērnu attīstības vispārīgs raksturojums 3. Bērnu savstarpējās attiecības 4-6 gadu vecumā 4. Bērnu savstarpējo attiecību sekmēšana caur dramatizācijas rotaļām Pētījuma metodes: Pedagoģiskās un psiholoģiskās literatūras izpēte un analīze Darba rezultāti: Teorētiskais pētījums sniedz strukturētu pārskatu par 4-6 gadus vecu bērnu savstarpējo attiecību specifiku, un rotaļām kā metodi to veidošanā, nostiprināšanā un uzlabošanā. Darba izmantojamība…