Search results for "TERPENES"
showing 10 items of 470 documents
Faceted phospholipid vesicles tailored for the delivery of Santolina insularis essential oil to the skin
2015
The aim of this work was to formulate Santolina insularis essential oil-loaded nanocarriers, namely Penetration Enhancer containing Vesicles (PEVs), evaluate the physico-chemical features and stability, and gain insights into their ability to deliver the oil to the skin.S. insularis essential oil was obtained by steam distillation, and was predominantly composed of terpenes, the most abundant being β-phellandrene (22.6%), myrcene (11.4%) and curcumenes (12.1%). Vesicles were prepared using phosphatidylcholine, and ethylene or propylene glycol were added to the water phase (10% (v/v)) to improve vesicle performances as delivery systems. Vesicles were deeply characterized by light scattering,…
Phytotoxic Activities of Mediterranean Essential Oils
2010
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Study of quantitative and qualitative variations in essential oils of Sicilian Rosmarinus officials L.
2015
In this study the chemical characterizations of 10 sicilian biotypes of Rosmarinus officinalis L. essential oils are reported. The main goal was to analyze the relationship between the essential oils yield and the geographical distribution of the species plants. The essential oils were analyzed by GC-FID and GC-MS. The statistical methods Hierarchical Cluster Analysis and Principal Component Analysis were used to cluster biotypes according to the chemical composition of the essential oils. The essential oil yield ranged from 0.8 - 2.3 (v/w). 82 compounds have been identified, these represent 96.7-99.9% of the essential oil. The compounds mostly represented in the essential oils were: 1.8- C…
Drimane Sesquiterpenoids from Marasmius sp. Inhibiting the Conidial Germination of Plant-Pathogenic Fungi
2012
From the basidiomycete Marasmius sp., strain IBWF 96046, three new sesquiterpenoids based on the drimane skeleton were isolated and named marasmene B and marasmals B and C. In this study, their isolation, structure elucidation, and biological evaluation are described. The compounds have a pronounced inhibitory effect on the conidial germination of several plant-pathogenic fungi.
Cross-linked natural IntegroPectin films from citrus biowaste with intrinsic antimicrobial activity
2022
AbstractPectin recovered via hydrodynamic cavitation (IntegroPectin) from lemon and grapefruit agri-food waste intrinsically containing antimicrobial bioactive substances (flavonoids, phenolic acids, terpenes, and terpenoids) was used to generate innovative and eco-compatible films that efficiently inhibit the growth of Gram-negative pathogens. Extensive characterization of films confirmed the presence of these substances, which differently interact with the polysaccharide polymer (pectin), plasticizer (glycerol), surfactant (Tween 60), and cross-linker (Ca2+), conferring to these films a unique structure. Besides, IntegroPectin-based films constitute versatile systems for the sustained, co…
Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase.
2002
Background— Estrogens can upregulate endothelial nitric oxide synthase (eNOS) in human endothelial cells by increasing eNOS promoter activity and enhancing the binding activity of the transcription factor Sp1. Resveratrol, a polyphenolic phytoalexin found in grapes and wine, has been reported to act as an agonist at the estrogen receptor. Therefore, we tested the effect of this putative phytoestrogen on eNOS expression in human endothelial cells. Methods and Results— Incubation of human umbilical vein endothelial cells (HUVEC) and HUVEC-derived EA.hy 926 cells with resveratrol for 24 to 72 hours upregulated eNOS mRNA expression in a time- and concentration-dependent manner (up to 2.8-fold)…
Grapefruit essential oils inhibit quorum sensing of Pseudomonas aeruginosa.
2019
Citrus essential oils are used in food to confer flavor and aromas. The citrus essential oils have been granted as GRAS and could be used as antimicrobial additives to control bacterial quorum sensing from potential food bacterial pathogens. The chemical composition and inhibitory activity of Citrus paradisi (grapefruit) essential oils obtained by cold-pressed method (EOP) and cold-pressed method followed by steam distillation, against Pseudomonas aeruginosa were determined . The GC-MS analyses of the oil indicated the amount of the essential oil components was highest with D-limonene in both cases. However, the extraction method modified the chemical composition. EOP had higher amount of …
Parthenolide induces caspase-independent and AIF-mediated cell death in human osteosarcoma and melanoma cells
2013
The mechanism of the cytotoxic effect exerted by parthenolide on tumor cells is not clearly defined today. This article shows that parthenolide stimulates in human osteosarcoma MG63 and melanoma SK-MEL-28 cells a mechanism of cell death, which is not prevented by z-VAD-fmk and other caspase inhibitors. In particular treatment with parthenolide rapidly stimulated (1-2 h) reactive oxygen species (ROS) generation by inducing activation of extracellular signal-regulated kinase 1/2 (ERK 1/2) and NADPH oxidase. This event caused depletion of thiol groups and glutathione, NF-κB inhibition, c-Jun N-terminal kinase (JNK) activation, cell detachment from the matrix, and cellular shrinkage. The increa…
Calcium in plant defence‐signalling pathways
2006
In plant cells, the calcium ion is a ubiquitous intracellular second messenger involved in numerous signalling pathways. Variations in the cytosolic concentration of Ca2+ ([Ca2+]cyt) couple a large array of signals and responses. Here we concentrate on calcium signalling in plant defence responses, particularly on the generation of the calcium signal and downstream calcium-dependent events participating in the establishment of defence responses with special reference to calcium-binding proteins.
Phytochemical Studies on Ptilostemon greuteri Raimondo & Domina (Compositae)
2012
Ptilostemon greuteri Raimondo & Domina is described as a new species and its growth is limited to the area of the province of Trapani. Essential oils of aerial parts of P. greuteri were analized by gas chromatography-mass spectrometry (GC-MS). The analysis of acetonic extract of aerial parts led to identification of triterpenes components: α-amyrin, β-amyrin, α-amyrin acetate, β-amyrin acetate, lupeol, lupeol acetate and taraxasterol. CC and preparative TLC of acetonic extracts has yielded lignan lactone and a sesquiterpene lactone that have been isolated previously from other Ptilostemon species.