Search results for "TERPENOID"

showing 10 items of 221 documents

Chemical Composition Analysis, Antimicrobial Activity and Cytotoxicity Screening of Moss Extracts (Moss Phytochemistry)

2015

Mosses have been neglected as a study subject for a long time. Recent research shows that mosses contain remarkable and unique substances with high biological activity. The aim of this study, accordingly, was to analyze the composition of mosses and to screen their antimicrobial and anticancer activity. The total concentration of polyphenols and carbohydrates, the amount of dry residue and the radical scavenging activity were determined for a preliminary evaluation of the chemical composition of moss extracts. In order to analyze and identify the substances present in mosses, two types of extrahents (chloroform, ethanol) and the GC/MS and LC-TOF-MS methods were used. The antimicrobial activ…

PhytochemistryCarbohydratesPharmaceutical ScienceAntineoplastic AgentsApoptosisLC-TOF-MSBryophytaArticleGas Chromatography-Mass SpectrometryAnalytical Chemistrylcsh:QD241-441MiceAnti-Infective Agentsantiradical activitylcsh:Organic chemistryCell Line TumorDrug DiscoveryBotanyAnimalsHumansFood sciencePhysical and Theoretical ChemistrypolyphenolsCell Proliferationamino acidsantimicrobial activitybiologyPlant ExtractsGC/MSOrganic ChemistryBiological activitybiology.organism_classificationAntimicrobialMossTerpenoidRatsChemistry (miscellaneous)PolyphenolMCF-7 CellsextractionMolecular MedicinecytotoxicityGas chromatography–mass spectrometryBacteriaMolecules
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Chemical composition of the essential oil of Salvia multicaulis Vahl. var. simplicifolia Boiss. growing wild in Lebanon

2004

The essential oil of aerial parts of Salvia multicaulis Vahl. var. simplicifolia Boiss. (Lamiaceae) growing wild in Lebanon was obtained by hydrodistillation and was analysed by GC and GC-MS. 67 compounds constituting 95.2% of the oil were identified, the major components being alpha-copaene (8.0%), alpha-pinene (6.6%), myrtenol (5.7%), trans-sabinyl acetate (5.3%).

PineneChromatographybiologyTraditional medicineStereochemistryMonoterpeneOrganic ChemistryGeneral MedicinePharmacognosybiology.organism_classificationBiochemistryGas Chromatography-Mass SpectrometryTerpenoidAnalytical Chemistrylaw.inventionchemistry.chemical_compoundchemistrylawMyrtenolOils VolatileLamiaceaeSalviaLebanonEssential oilSalvia multicaulisJournal of Chromatography A
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Triterpenoid saponins from the cultivar “Green Elf” of Pittosporum tenuifolium

2021

Four oleanane-type glycosides were isolated from a horticultural cultivar “Green Elf” of the endemic Pittosporum tenuifolium (Pittosporaceae) from New Zealand: three acylated barringtogenol C glycosides from the leaves, with two previously undescribed 3-O-β-d-glucopyranosyl-(1→2)-[α-l-arabinopyranosyl-(1→3)]-β-d-glucuronopyranosyl-21-O-angeloyl-28-O-acetylbarringtogenol C, 3-O-β-d-galactopyranosyl-(1→2)-[α-l-arabinopyranosyl-(1→3)]-β-d-glucuronopyranosyl-21-O-angeloyl-28-O-acetylbarringtogenol C, and the known 3-O-β-d-glucopyranosyl-(1→2)-[α-l-arabinopyranosyl-(1→3)]-β-d-glucuronopyranosyl-21-O-angeloyl-28-O-acetylbarringtogenol C (Eryngioside L). From the roots, the known 3-O-β-d-glucopyra…

PittosporaceaeSaponinPittosporaceaePharmaceutical ScienceOrganic chemistry01 natural sciencesTAS1R2/TASR3Analytical ChemistryTriterpenoidTAS1R3QD241-441sweet tasteDrug Discovery[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyCultivarPhysical and Theoretical Chemistrytaste inhibitor2. Zero hungerchemistry.chemical_classificationbiologyTraditional medicine010405 organic chemistryPittosporum tenuifoliumbarringtogenol CGlycosideSweet tastebiology.organism_classification0104 chemical sciencesPittosporum tenuifolium010404 medicinal & biomolecular chemistry<i>Pittosporum tenuifolium</i>chemistryChemistry (miscellaneous)Molecular Medicine[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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Essential oils of Chiliadenus lopadusanus (Asteraceae).

2013

The essential oils from the leaves and flowers of Chiliadenus lopadusanus growing on Lampedusa Island were obtained by hydrodistillation and analyzed by GC-MS. The major component was camphor (39.4% in the leaves and 24.0% in the flowers), followed in the leaves by torreyol (6.7%), t-cadinol (5.2%) and 1,8-cineole (3.8%), while in the flowers by t-cadinol (15.2%), t-muurolol (5.1%) and torreyol (4.5%). Among the compounds identified, several seem to play a role in antibacterial, antifungal, allelopathic and spasmolytic activity. In addition, several compounds identified in this study seem to influence the attraction of Megachile (Eutricharaea) apicalis (Megachilidae) and Halictus (Seladonia…

PollinatorSettore BIO/07 - EcologiaChiliadenuInsectavolatiles Chiliadenus pollinators terpenoids camphor.FlowersAsteraceaeEssential oilTerpenoidPlant LeavesSettore AGR/11 - Entomologia Generale E ApplicataItalySettore CHIM/03 - Chimica Generale E InorganicaSettore BIO/03 - Botanica Ambientale E ApplicataOils VolatileAnimals
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Apoptotic activities of Mediterranean plants

2020

Medicinal plants from the Mediterranean region show great potential in the improvement of health and in the prevention of disease. Epidemiological studies indicate that some of these plants reduce the incidence of inflammatory diseases and cancer by inducing programmed cell death, thus arresting proliferation. These medicinal properties are related to the presence of compounds such as phenolics with antioxidant properties or nonphenolic compounds, including essential oils, terpenoids, or saponins. Our aim is to review role of different medicinal plants and phytochemicals in apoptosis and disease prevention and the mechanism of action implicated in these beneficial effects. Sin financiación …

Programmed cell deathAntioxidantTraditional medicinePaís mediterráneomedicine.medical_treatmentfungiDiseaseBiologyTerpenoidMechanism of actionApoptosisPlanta medicinalNutriciónmedicineDisease preventionmedicine.symptomMedicinal plants
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Enzyme-catalysed transformations of ent-kaurane diterpenoids

2005

Several acetyl derivatives of linearol, atractyligenin and atractylitriol were obtained through enzyme-catalysed acetylation and deacetylation reactions. In most reactions lipases showed regio- and stereoselective behaviour, allowing a family of novel compounds to be prepared. Fil: Monsalve, Leandro Nicolas. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Unidad de Microanálisis y Métodos Físicos en Química Orgánica. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Unidad de Microanálisis y Métodos Físicos en Química Orgánica; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y …

Química OrgánicaACETYLATIONENZYME CATALYSISChemistryStereochemistryDEACETYLATIONOrganic ChemistryENT-KAURANESCiencias QuímicasDITERPENOIDSPhysical and Theoretical ChemistryEnt kauraneCIENCIAS NATURALES Y EXACTAS
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Cytotoxic Acacic Acid Glycosides from the Roots of Albizia coriaria

2009

Two new oleanane-type saponins, coriariosides A (1) and B (2), along with a known saponin, gummiferaoside C (3), were isolated from the roots of Albizia coriaria. Their structures were established by extensive analysis of 1D and 2D NMR experiments (COSY, ROESY, TOCSY, HSQC, and HMBC) and mass spectrometry. Compounds 1 and 3 when tested for cytotoxicity against two colorectal human cancer cells showed activity against the HCT 116 (IC50 4.2 microM for 1 and 2.7 microM for 3) and HT-29 (IC50 6.7 microM for 1 and 7.9 microM for 3) cell lines.

SaponinPharmaceutical ScienceAlbizziaPharmacognosyPlant RootsAnalytical ChemistryTriterpeneCoriariaDrug DiscoveryBotanyHumansCameroonOleanolic AcidMedicinal plantsNuclear Magnetic Resonance BiomolecularPharmacologychemistry.chemical_classificationPlants MedicinalMolecular StructurebiologyOrganic ChemistryGlycosideSaponinsHCT116 Cellsbiology.organism_classificationAlbiziaAntineoplastic Agents PhytogenicTriterpenesTerpenoidComplementary and alternative medicinechemistryMolecular MedicineDrug Screening Assays AntitumorHT29 CellsJournal of Natural Products
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Arboreasides A−E, Triterpene Saponins from the Bark of Cussonia arborea

2009

Five new triterpene saponins, arboreasides A-E (1-5), and two known saponins, ciwujianoside C(3) and 23-hydroxyursolic acid 28-O-alpha-L-rhamnopyranosyl-(1--4)-beta-D-glucopyranosyl-(1--6)-beta-D-glucopyranosyl ester, were isolated from the bark of Cussonia arborea. The structures were established using extensive 1D and 2D NMR spectroscopic analyses and mass spectrometry.

SaponinPharmaceutical SciencePharmacognosyAnalytical ChemistryTriterpeneDrug DiscoveryBotanyCameroonAraliaceaeNuclear Magnetic Resonance BiomolecularPharmacologychemistry.chemical_classificationMolecular StructurebiologyOrganic ChemistryGlycosideSaponinsbiology.organism_classificationTriterpenesTerpenoidComplementary and alternative medicinechemistryvisual_artPlant Barkvisual_art.visual_art_mediumMolecular MedicineAraliaceaeBarkCussonia arboreaJournal of Natural Products
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New triterpenoid estersaponins from the root barks of Pittosporum verticillatum subsp. verticillatum and evaluation of cytotoxicities

2013

The phytochemical investigation of the root barks of Pittosporum verticillatum Bojer subsp. verticillatum led to the isolation of three new triterpene saponins, 3-O-[β-D-glucopyranosyl-(1→2)]-[α-L-arabinopyranosyl-(1→3)]-[α-L-arabinofuranosyl-(1→4)]-β-D-glucuronopyranosyl-21-O-(2-acetoxy-2-methylbutanoyl)-R1-barrigenol (1), 3-O-[β-D-glucopyranosyl-(1→2)]-[α-L-arabinopyranosyl-(1→3)]-[α-L-arabinofuranosyl-(1→4)]-β-D-glucuronopyranosyl-21-O-(2-acetoxy-2-methylbutanoyl)-28-O-acetyl-R1-barrigenol (2), 3-O-[β-D-glucopyranosyl-(1→2)]-[α-L-arabinopyranosyl-(1→3)]-[α-L-arabinofuranosyl-(1→4)]-β-D-glucuronopyranosyl-21-O-β,β-dimethylacryloyl-22-O-angeloyl-R1-barrigenol (3), and one known saponin sen…

Senaciapittoside BStereochemistrySaponinPlant RootsCell LineTerpeneTriterpenoidTriterpeneCell Line TumorNeoplasmsDrug DiscoveryAnimalsHumansRosalesPharmacologychemistry.chemical_classificationMolecular StructurebiologyPlant ExtractsGeneral MedicineSaponinsPittosporumbiology.organism_classificationTriterpenesRatschemistryPhytochemicalPlant BarkHuman cancerFitoterapia
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Electrophysiological and behavioural responses of the housefly to “sweet” volatiles of the flowers of Caralluma europaea (Guss.) N.E. Br.

2013

In sapromyiophilous plants, up to date, long range attraction of fly pollinators has been thoroughly investigated and attributed to ‘‘fetid’’ floral compounds, while the ‘‘sweet’’ floral scent fraction has not been spe- cifically investigated and its role has received little atten- tion. The aim of the present study was to verify if terpenoids, which are the main compounds of the floral bouquet of Caralluma europaea, play a role in the attrac- tion of its pollinator Musca domestica. Terpinolene, a- terpinene and linalool, described as the three main volatiles of the flowers of C. europaea, were evaluated in electro- physiological investigations and blends of these com- pounds as well as the…

Settore BIO/07 - EcologiaCaralluma europaeapollinationEcologybiologybiology.organism_classificationAttractionTerpenoidchemistry.chemical_compoundApteranthes europaea subsp. europaeaSettore AGR/11 - Entomologia Generale E ApplicataLinaloolchemistrysapromyiophilyPollinatorInsect ScienceFloral scentBotanySettore BIO/03 - Botanica Ambientale E ApplicataMusca domesticaHouseflyAgronomy and Crop ScienceMuscaEcology Evolution Behavior and Systematics
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