Search results for "TERT"

showing 10 items of 1210 documents

Seriāla "Reiz sensenos laikos" naratīva analīze

2017

Bakalaura darbs "Seriāla "Reiz sensenos laikos" naratīva analīze" piedāvā ielūkoties kā dažādas aktuālas Disneja filmas, populārā rietumu literatūra, folklora un pasakas tiek ienestas un interpretētas jaunā, mūsdienīgā produktā - seriālā. Darbs aplūko teorijas, kas saistītas ar pasaku un seriālu uzbūvi, kā arī kino naratīvu, lai varētu veikt analīzi, kā seriāls "Reiz sensenos laikos" atbilst klasiskai pasakas struktūrai. Ar kvantitatīvās kontentanalīzes palīdzību tiek noteikts, kādas ir personāžu īpašības, iezīmes un kādas funkcijas personāžs veic pasakas kontekstā. Bet ar semiotikas palīdzību tiek noteikts, kādi instrumenti tiek lietoti, lai seriālā paustu vēlamo domu. Darba rezultāti atkl…

seriālsintertekstualitātenaratīvsKomunikācijas zinātnepasakakino
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Síntesis diasteroselectiva de sistemas terpénicos con esqueleto de isoespongiano y 25-norescalarano

2012

Esta Tesis describe la síntesis de sistemas terpénicos de tipo isoespongiánico y 25-norescalaránico. En el primer capítulo se describe la síntesis de sistemas diterpénicos con esqueleto carbocíclico de isoespongiano a partir del monoterpeno (S)-carvona. En la misma este monoterpeno es empleado como sintón quiral del anillo C e incorporado al esqueleto tretracíclico de isoespongiano vía una estrategia sintética del tipo C→ABC→ABCD, empleando para su elaboración como etapas clave una reacción de Diels-Alder intramolecular de un 1,3,9-decatrieno para la construcción de los anillos AB y una reacción de metátesis de cierre de anillo de un éter de bis-alilo para la construcción del anillo D. Esta…

sesterterpenosactividad biológicaterpenossíntesisproductos naturales:QUÍMICA::Química orgánica [UNESCO]diterpenosUNESCO::QUÍMICA::Química orgánicacadena respiratoria mitocondrial
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Paramedia : thresholds of the social text

2017

This work is an adaptation of Gerard Genette’s theory of paratexts to social media. Paratexts are information surrounding texts, and usually helping the user to decide whether or not to consume a text. In social media, a plurality of new information surrounds texts we read every day. They are dynamic by nature and have different authors: the social platforms, like Facebook or YouTube; the authors of texts, and the users who comment and share them. This collection of four articles will debate the ethos in social media, what is an author in social media, what are the identified paratexts in selected social media websites and the limits of interpretation of paratexts in contemporary Brazilian …

sisältötuotantosocial mediaverkkokirjoittaminenhypertekstiperitekstisosiaalinen mediaparatextsdigital contentcontent strategydata-driven decision-makingintertextualityperitextsdigitaalinen kulttuuriparatekstiliterary theorytekijyys
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Connecting others: Does a tertius iungens orientation shape the relationship between research networks and innovation?

2021

Research on social networks and innovation emphasizes that individuals spanning structural holes and crossing institutional boundaries have more opportunities for knowledge recombination and innovation involvement. However, transforming the potential knowledge and resources available through personal networks to attain innovation can be difficult for the focal individual. Using an ego-network approach, this study examines whether and to what extent an individual strategic orientation to cooperation (i.e. tertius iungens) contributes to strengthening the relation between two personal network properties (structural and institutional separation) and involvement in innovation. Our analysis is c…

social networksKnowledge managementStrategy and ManagementbiomedicineContext (language use)Management Science and Operations Research050905 science studiesStrategic orientation[INFO.INFO-SI]Computer Science [cs]/Social and Information Networks [cs.SI]Personal networkstructural separationOrientation (mental)Management of Technology and InnovationPhenomenon0502 economics and businesstertius iungensnetwork heterogeneityStructural holesBiomedicineSocial networkbusiness.industry05 social sciencesinnovationstructural holesBiomedicineinstitutional separationBusiness0509 other social sciences050203 business & management
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Do humans dream of prophetic robots?

2020

Social robotics is a technology that, as its definition varies, encompasses conceptually diverse fields materializing in innovations from simple chatbots to sophisticated androids talking about the peaceful coexistence of humans and robots. The advances in social robotics have led to promising applications in education, work, entertainment, and even religion. Yet a measure of fear and confusion about the capabilities of contemporary and future robots exists, with one of the reasons being the presentation of some contemporary robots as being more advanced than they really are.

sosiaalinen robotiikkaSocial Psychologymedia_common.quotation_subjectihmisen ja tietokoneen vuorovaikutusrobotiikkaEntertainmentPresentationandroiditmedicineSociologyDreamConfusionmedia_commonSimple (philosophy)Cognitive scienceSocial robotCommunicationteknologinen kehityspääkirjoituksetPeaceful coexistenceHuman-Computer InteractionrobotitinteraktiivisuusRobotälytekniikkamedicine.symptom
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Autorreflexión pedagógica

2019

The autobiographical reflection on school learning makes it possible to explain how personal life guidelines are loading teaching activity with experiences. Educational time does not consist only of a linear narration, but works as the evocation of temporal and spatial memories of an explanation of the present. Personal life is intertwined with school reflection to give meaning to what we decide from teaching

studentElsa Amanda The autobiographical reflection on school learning makes it possible to explain how personal life guidelines are loading teaching activity with experiences. Educational time does not consist only of a linear narration1137-7038 8537 Arxius de sociologia 558787 2019 41 7605679 Autorreflexión pedagógica R. De MorenoestudianteUNESCO::SOCIOLOGÍApedagogíabut works as the evocation of temporal and spatial memories of an explanation of the present. Personal life is intertwined with school reflection to give meaning to what we decide from teaching Autobiografíapedagogy 29 41:SOCIOLOGÍA [UNESCO]Autobiographyteachingdocencia
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Towards to Sustainable Tourism – Framework, Activities and Dimensions

2013

Abstract The tourism sector is most often associated with the attractive places worth to visit, sights to be seen or entertainment. In the general opinion, tourist sector does not have any negatives - it causes hundreds of tourists coming to the country who leave money, provide jobs and disseminate local space. On the other hand, heavy tourist traffic causes a significant damage, not only to the environment, which may lead to its degradation, but it also has a negative impact on the local community - for example, tourists bring a Coke or McDonalds’, the things unknown for one region, for example and they can lead to tooth decay or obesity. Fortunately, for many years many attempts have been…

sustainable developmentTourism geographyGeneral EngineeringEnergy Engineering and Power TechnologyLocal communityEntertainmentSightEcotourismtourismsustainable tourismBusinessMeaning (existential)Marketingeco-tourism.TourismSustainable tourismProcedia Economics and Finance
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Synthesis and Structure-Affinity Relationships of Spirocyclic Benzopyrans with Exocyclic Amino Moiety

2019

σ1 and/or σ2 receptors play a crucial role in pathological conditions such as pain, neurodegenerative disorders, and cancer. A set of spirocyclic cyclohexanes with diverse O-heterocycles and amino moieties (general structure III) was prepared and pharmacologically evaluated. In structure-activity relationships studies, the σ1 receptor affinity and σ1:σ2 selectivity were correlated with the stereochemistry, the kind and substitution pattern of the O-heterocycle, and the substituents at the exocyclic amino moiety. cis-configured 2-benzopyran cis-11b bearing a methoxy group and a tertiary cyclohexylmethylamino moiety showed the highest σ1 affinity ( Ki = 1.9 nM) of this series of compounds. In…

synthesisexocyclic amino moietyReceptors Opioid mudocking studieCrystallography X-RayLigands01 natural sciencesopioid receptorschemistry.chemical_compoundProtein structureDrug DiscoveryMoiety0303 health sciencesσ1 receptor ligandsstructure (σ1) affinity relationshipmolecular dynamicBenzyl groupMolecular MedicinesynthesiBenzopyransSelectivityHydrophobic and Hydrophilic Interactionsfree binding enthalpyStereochemistrychange of receptor profileMolecular Dynamics Simulation03 medical and health sciencesStructure-Activity Relationshipσ1 receptor ligands; spirocyclic compounds; benzopyrans; benzofurans; exocyclic amino moiety; synthesis; structure (σ1) affinity relationships; σ1 antagonistic activity; receptor selectivity; molecular dynamics; docking studies; free binding enthalpy; X-ray crystal structure; opioid receptors; MOR affinity; change of receptor profile; structure MOR affinity relationshipsstructure (σ1) affinity relationshipsStructure–activity relationshipHumansReceptors sigmaBenzopyransSpiro Compoundsspirocyclic compoundBinding siteMOR affinity030304 developmental biologybenzopyranbenzofuransσ1 receptor ligandBinding Sitesspirocyclic compoundsreceptor selectivitystructure MOR affinity relationshipsdocking studiesbenzofuranopioid receptorX-ray crystal structuremolecular dynamics0104 chemical sciencesProtein Structure Tertiary010404 medicinal & biomolecular chemistrychemistrySalt bridgeσ1 antagonistic activity
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Eukaryotic rRNA Modification by Yeast 5-Methylcytosine-Methyltransferases and Human Proliferation-Associated Antigen p120.

2015

International audience; Modified nucleotide 5-methylcytosine (m(5)C) is frequently present in various eukaryotic RNAs, including tRNAs, rRNAs and in other non-coding RNAs, as well as in mRNAs. RNA: m(5)C-methyltranferases (MTases) Nop2 from S. cerevisiae and human proliferation-associated nucleolar antigen p120 are both members of a protein family called Nop2/NSUN/NOL1. Protein p120 is well-known as a tumor marker which is over-expressed in various cancer tissues. Using a combination of RNA bisulfite sequencing and HPLC-MS/MS analysis, we demonstrated here that p120 displays an RNA:m(5)C-MTase activity, which restores m(5)C formation at position 2870 in domain V of 25S rRNA in a nop2 Delta …

tRNA MethyltransferasesSaccharomyces cerevisiae Proteinslcsh:RNuclear Proteinslcsh:MedicineMethyltransferasesSaccharomyces cerevisiaeProtein Structure TertiaryRNA Ribosomal5-MethylcytosineHumans[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biologylcsh:Qlcsh:Science[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyProtein BindingResearch ArticlePLoS ONE
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Learnings from the Finnish Game Industry

2016

The motivation behind our research was the rapid growth and business wins of world-class Finnish game companies, like Supercell, as well as the success of other game companies in Finland. In particular, Supercell's growth is something that has not been heard of before and this raised the interest to research what game companies have been doing right. Supercell is not the only Finnish success. Rovio is also well known and has the roots for success from few years before. There are also other game companies in Finland that have succeeded and this motivated us to investigate what is happening behind the game industry and what could be learned from there that could be applied to other software i…

ta113Engineeringgame industry040301 veterinary sciencesbusiness.industryStar (game theory)0402 animal and dairy scienceContext (language use)Advertising04 agricultural and veterinary sciencesPublic relations040201 dairy & animal scienceMountain sheepNewspaper0403 veterinary scienceEntertainmentcvg.developerOrder (exchange)NarrativecvgGame DeveloperbusinessFinland
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