Search results for "TERT"

ChemInform Abstract: A Simple Preparation of Mono-tert-butyl Benzyloxycarbonyl-L-glutamates.

2010

(1995). A SIMPLE PREPARATION OF MONO-tert-BUTYL BENZYLOXYCARBONYL-L-GLUTAMATES. Organic Preparations and Procedures International: Vol. 27, No. 3, pp. 378-380.

A SIMPLE PREPARATION OF MONO-tert-BUTYL BENZYLOXYCARBONYL-L-GLUTAMATES

1995

(1995). A SIMPLE PREPARATION OF MONO-tert-BUTYL BENZYLOXYCARBONYL-L-GLUTAMATES. Organic Preparations and Procedures International: Vol. 27, No. 3, pp. 378-380.

The Di-Tert-Butyl Oxymethylphosphonate Route to the Antiviral Drug Tenofovir

2020

<div>The present manuscript describes a simple, two step synthesis of tenofovir from HPA through phosphonomethalation with a novel doubly protected oxymethylphosphonate electrophile. The crystalline electrophile can be prepared in a simple reaction sequence and can be deblocked more easily than its ditehyl analogue involved in the current commercial process for making the drug.</div><div>The approach is general and can also be used for the preparation of related antivirals and the synthesis of adefovir is described as well.<br></div>

The ionic tin(IV) complex tri-μ2-methoxy-μ3-oxo-tris[di-tert-butyltin(IV)] tri-μ2-methoxy-bis[tert-butyldimethoxystannate(IV)]

2004

The solid-state of the title compound, [Sn3(C4H9)6(CH3O)3O][Sn2(C4H9)2(CH3O)7], consists of distinct [tBu6Sn3(μ-OCH3)3(μ3-O)]+ cations and [tBu2Sn2(OCH3)4(μ-OCH3)3]− anions, apparently formed as a result of slow hydro­lysis of pure di(tert-butyl)­di­methoxy­stannane, tBu2Sn(OCH3)2. In the monocation, the coordin­ation about the Sn atoms is distorted trigonal bipyramidal, and, in the monoanion, distorted octahedral. The trigonal bipyramidal arrangement induces planarity of the Sn3O4 motif.

Redetermination of 5,11,17,23-tetra-tert-butyl-25,27-di(ethoxycarbonylmethoxy)-26,28-dihydroxycalix[4]arene chloroform disolvate at low temperature

2003

The title compound, C52H68O8·2CHCl3, previously reported by Ferguson et al. [Supramol. Chem. (1996), 7, 223–228], has been rerefined against new intensity data. The geometric parameters are comparable, as far as they are available. However, the results of the present structure determination are of significantly higher precision.

Converging and Diverging Synthetic Strategies to Tetradentate (N,N′)-Diaminomethyl,(P,P′)-Ferrocenyl Ligands: Influence of tert-Butyl Groups on Ferro…

2015

Hexasubstituted hybrid tetradentate (N,N′,P,P′)-ferrocenes bearing phosphino and aminomethyl groups, plus hindering tert-butyl moieties, were synthesized by using two different strategies: a “diverging” synthesis involving successive functionalization of preformed di-tert-butylated ferrocene and a “converging” assembly of the species from appropriately substituted cyclopentadienyl rings. While the new cyclopentadienyl salts formed are of interest, their assembly with iron dichloride used as a “converging” way to produce tetradentate ferrocene ligands presented several drawbacks. Conversely, the synthesis of new tert-butylated (aminomethyl)ferrocene derivatives was found convenient to furthe…

26,28-Diallyloxy-5,11,17,23-tetra-tert-butyl-25,27-bis(cyanomethoxy)calix[4]arene in the partial cone conformation

2006

The title compound, C54H66N2O4, crystallizes with two mol­ecules in the asymmetric unit. Both adopt the typical partial cone conformation which was also found for 26,28-diall­yloxy-5,17-di-tert-butyl-25,27-bis­(cyano­meth­oxy)-11,23-dinitrocalix[4]arene [Danila, Bohmer & Bolte (2005). Org. Biomol. Chem. 3, 3508–3513]. The crystal structure of the title compound in the 1,2-alternate conformation has been determined recently [Danila, Bohmer & Bolte (2005). Org. Biomol. Chem. 3, 3508–3513].

Bis(tert-butylammonium) oxalate

2006

The component species in the title compound, 2C4H12N2+·C2O42−, inter­act by way of N—H⋯O hydrogen bonds, resulting in a layered network. N and two C atoms of the cation possess site symmetry m and the C atom of the anion has site symmetry 2.

Antineoplastika, 19. Mitt.: Darstellung vonN-[2-Chlor-4-diethylamino-(1,3,5-triazin-6-yl)]-aminosäuren

1990

4-Chloro-N-methyl-N-nitroaniline

1998

The molecular structure of (p-ClC 6 H 4 )(CH 3 )NNO 2 (or C 7 H 7 ClN 2 O 2 ) contains a planar NNO 2 nitroamino group which is twisted about the N-C phenyl bond by ca 68° from the plane of the aromatic ring. The structural data are in agreement with the spectral results and indicate that there is no conjugation between the aromatic sextet and the nitroamino group. There are no specific intermolecular interactions.