Search results for "TF"

Consensus guidelines for the detection of immunogenic cell death

2014

Apoptotic cells have long been considered as intrinsically tolerogenic or unable to elicit immune responses specific for dead cell-associated antigens. However, multiple stimuli can trigger a functionally peculiar type of apoptotic demise that does not go unnoticed by the adaptive arm of the immune system, which we named "immunogenic cell death" (ICD). ICD is preceded or accompanied by the emission of a series of immunostimulatory damage-associated molecular patterns (DAMPs) in a precise spatiotemporal configuration. Several anticancer agents that have been successfully employed in the clinic for decades, including various chemotherapeutics and radiotherapy, can elicit ICD. Moreover, defect…

Sociālo mediju ziņojumu plūsmu pārskata vietne.

2016

Kvalifikācijas darba “Sociālo mediju ziņojumu plūsmu pārskata vietne” mērķis ir izstrādāt tīmekļa vietni, kura spētu palīdzēt, piemēram, kāda pasākuma organizatoram sekot līdzi cilvēku attieksmei un attiecīgi veikt izmaiņas pašreizējā vai nākamajos pasākumos, lai uzlabotu cilvēku labsajūtu un pieredzi. Šī tīmekļa vietne ir pieejama caur tīmekļa pārlūku jebkuram interesantam, taču administratora pieeja tiek atļauta tikai kādai iepriekš definētai cilvēku grupai. Tīmekļa vietnes administrators spēs izveidot jaunu mediju sienu, kurā tiks parādītas dažādas cilvēku sīkziņas atkarībā no administratora izvēlētajiem parametriem sienas izveidošanas brīdī. Sistēmas jebkuram lietotājiem būs iespējams a…

Synthetic individual binaural audio delivery by pinna image processing

2014

Purpose – The purpose of this paper is to present a system for customized binaural audio delivery based on the extraction of relevant features from a 2-D representation of the listener’s pinna. Design/methodology/approach – The most significant pinna contours are extracted by means of multi-flash imaging, and they provide values for the parameters of a structural head-related transfer function (HRTF) model. The HRTF model spatializes a given sound file according to the listener’s head orientation, tracked by sensor-equipped headphones, with respect to the virtual sound source. Findings – A preliminary localization test shows that the model is able to statically render the elevation of a vi…

Projections of temperature-related excess mortality under climate change scenarios.

2017

Background: Climate change can directly affect human health by varying exposure to non-optimal outdoor temperature. However, evidence on this direct impact at a global scale is limited, mainly due to issues in modelling and projecting complex and highly heterogeneous epidemiological relationships across different populations and climates. Methods: We collected observed daily time series of mean temperature and mortality counts for all causes or non-external causes only, in periods ranging from Jan 1, 1984, to Dec 31, 2015, from various locations across the globe through the Multi-Country Multi-City Collaborative Research Network. We estimated temperature–mortality relationships through a tw…

Transcatheter radiofrequency perforation and stent implantation for palliation of pulmonary atresia in a 3060-g infant

1995

In a 3060-g infant with fibromuscular pulmonary atresia an open right ventricular outflow tract was created by means of interventional cardiological methods. Following two inadvertent perforations without sequelae or clinical symptoms, radiofrequency perforation and subsequent balloon dilatation were successfully performed. The implantation of a Palmaz iliac stent led to a predictable communication between the right ventricle and pulmonary artery.

Numerical simulation of transcatheter mitral valve replacement: The dynamic implication of LVOT obstruction in the valve-in-ring case.

2022

Transcatheter mitral valve replacement (TMVR) has been used for “off-label” treatment when annuloplasty band ring for mitral repair fails. However, the complex anatomy and function of the mitral valve may lead to fatal complications as a result of the left ventricular outflow tract (LVOT) obstruction in TMVR. We report the structural and hemodynamic response of LVOT obstruction resulting from TMVR with the Edwards SAPIEN 3 Ultra (S3) device. We modified the original Living Heart Human Model (LHHM) to account for a failed mitral valve with an annuloplasty band ring and simulated the cardiac beating condition in the setting of S3 device implantation. Findings demonstrated a high dynamic behav…

Zoom in on Dry Joy—Dissensus, Agonism and Democracy in Art Education

2021

Literature on art education often emphasizes dialogue as a preferred approach and as a way of practicing democratic education in museums and galleries. Dialogue-based tours in such contexts are often characterized by a sense of harmony and agreement. In contrast, this article discusses the democratic aspect and political potentiality when dissensus and agonism are used as central educational strategies. The point of departure for the discussion was a teaching session on the online platform Zoom with student teachers as part of their module on art and crafts at the University of Agder in Kristiansand, Norway, in spring 2020. Artworks from the exhibition Dry Joy, in S&oslash

GARCH models with changes in variance: An approximation to risk measurements

2003

This study aims to model volatility as an approximation to an optimum measurement of stock market risk because of the importance of this concept for, among other things, the proper management of portfolios. Following the proposal of Lamoureux and Lastrapes (1990), the authors consider that the high degree of persistence detected in GARCH models arises from a poor specification of the equation of the variance due to not considering the possible deterministic changes in the unconditional variance of the financial series. To determine the point in time as well as the duration of these changes, the proposal made by Inclan and Tiao (1994) is used. As an empirical application, whether or not the …

2019

Despite substantial advances in many different fields of neurorobotics in general, and biomimetic robots in particular, a key challenge is the integration of concepts: to collate and combine research on disparate and conceptually disjunct research areas in the neurosciences and engineering sciences. We claim that the development of suitable robotic integration platforms is of particular relevance to make such integration of concepts work in practice. Here, we provide an example for a hexapod robotic integration platform for autonomous locomotion. In a sequence of six focus sections dealing with aspects of intelligent, embodied motor control in insects and multipedal robots-ranging from comp…

The jets and disc of SS 433 at super-Eddington luminosities

2009

We examine the jets and the disc of SS 433 at super-Eddington luminosities with 600 times Eddington critical accretion rate by time-dependent two-dimensional radiation hydrodynamical calculations, assuming alpha-model for the viscosity. One-dimensional supercritical accretion disc models with mass loss or advection are used as the initial configurations of the disc. As a result, from the initial advective disc models with alpha =0.001 and 0.1, we obtain the total luminosities 2.5x10^{40} and 2.0x10^{40} erg/s. The total mass-outflow rates are 4x10^{-5} and 10^{-4} solar-mass/yr and the rates of the relativistic axial outflows in a small half opening angle of 1 degree are about 10^{-6} solar…