Search results for "TG"
showing 10 items of 2275 documents
Clinical and genetic update of corneal dystrophies.
2019
The International Committee for Classification of Corneal Dystrophies (IC3D) distinguishes between 22 distinct forms of corneal dystrophy which are predominantly autosomal dominant, although autosomal recessive and X-chromosomal dominant patterns do exist. Before any genetic examination, there should be documentation of a detailed corneal exam of as many affected and unaffected family members as possible, because detailed phenotypic description is essential for accurate diagnosis. Corneal documentation should be performed in direct and indirect illumination at the slit lamp with the pharmacologically dilated pupil. For the majority of the corneal dystrophies, a phenotype-genotype correlatio…
Treatment of cervicofacial actinomycosis: a report of 19 cases and review of literature
2013
Objectives: Actinomycosis is a chronic suppurative granulomatous infection caused by the Actinomyces genus. Orocervicofacial actinomycosis is the most common form of the disease, seen in up to 55% of cases. All forms of actinomycosis are treated with high doses of intravenous penicillin G over two to six weeks, followed by oral penicillin V. Large studies on cervicofacial actinomycosis are lacking. Therefore proper guidelines for treatment and treatment duration are difficult to establish. The aim of this study is to establish effective treatment and treatment duration for orocervicofacial actinomycosis. Study design: A Pubmed and Embase search was performed with the focus on treatment and …
Piloting a Smart Rollator : User experiences with technology-related motivation and physical activity
2021
Background: Improved life expectancy combined with suboptimal physical activity (PA)represents an increasingly salient public health challenge among the elderly. PA in late life is associated with fewer health problems in old age. Assistive information and communication technology might improve PA and alleviate health problems among the elderly.Objective: This pilot study aimed to quantitatively measure the motivational aspects relatedto rollator use and, by using qualitative interviews, outline how a Smart Rollator solution would motivate older adults to increase their PA in their everyday lives.Method: A total of 19 subjects between the ages of 63 and 91 years participated in the study. H…
Feasibility of a personal health technology-based psychological intervention for men with stress and mood problems: Randomized controlled pilot trial
2013
BackgroundWork-related stress is a significant problem for both people and organizations. It may lead to mental illnesses such as anxiety and depression, resulting in increased work absences and disabilities. Scalable interventions to prevent and manage harmful stress can be delivered with the help of technology tools to support self-observations and skills training. ObjectiveThe aim of this study was to assess the feasibility of the P4Well intervention in treatment of stress-related psychological problems. P4Well is a novel intervention which combines modern psychotherapy (the cognitive behavioral therapy and the acceptance and commitment therapy) with personal health technologies to deliv…
Group 1 ITI Consensus Report: The influence of implant length and design and medications on clinical and patient-reported outcomes
2018
The following article: Jung, R.E., Al-Nawas, B., Araujo, M., Avila-Ortiz, G., Barter, S., Brodala, N., ... Windisch, P. (2018). Group 1 ITI Consensus Report: The influence of implant length and design and medications on clinical and patient-reported outcomes. Clinical Oral Implants Research, 29(S16), 69-77, can be accessed at https://doi.org/10.1111/clr.13342. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Objectives: The aim of Working Group 1 was to address the influence of different local (implant length, diameter, and design) and systemic (medications) factors on clinical, radiographic, and patient‐re…
Frequency of polymorphisms of signal peptide of TGF-beta1 and -1082G/A SNP at the promoter region of Il-10 gene in patients with carotid stenosis
2006
The role of inflammation in atherosclerosis is well recognized. We have evaluated the allele frequencies of the +869T/C and +915G/C polymorphisms (SNPs) at the TGF-beta1 gene and -1082G/A SNP at IL-10 promoter sequence, two well-known immunosuppressive and anti-inflammatory cytokines, in patients with carotid stenosis. Our data suggest a lack of association between these SNPs and the susceptibility to atherosclerosis although other reports have demonstrated this association. These results may be due to the pleiotropic effects of the cytokines and/or differences in haplotype combination that should be investigated to elucidate the role of TGF-beta1 and IL-10 polymorphisms in atherosclerosis.
El debat pro i antifeminista a la literatura catalana medieval
1987
This 1987 PhD dissertation, was de facto supervised by professors Lola Badia (Universitat de Barcelona) and Alan Deyermond (Queen Mary University of London), although, because of legal limitations at that time, supervision was officially signed by another professor). This was a pioneer work in the field of women’s studies, particularly in the so-called “querelle des femmes”, although, as the dissertation study specifies, this label would only become known as such in post-medieval times. This work, then, does not deal with all misogynistic references in the whole corpus of medieval Catalan literature (that would be quite impossible in one publication), but only with those texts arguing for o…
What we learn about bipolar disorder from large-scale neuroimaging
2020
Abstract MRI‐derived brain measures offer a link between genes, the environment and behavior and have been widely studied in bipolar disorder (BD). However, many neuroimaging studies of BD have been underpowered, leading to varied results and uncertainty regarding effects. The Enhancing Neuro Imaging Genetics through Meta‐Analysis (ENIGMA) Bipolar Disorder Working Group was formed in 2012 to empower discoveries, generate consensus findings and inform future hypothesis‐driven studies of BD. Through this effort, over 150 researchers from 20 countries and 55 institutions pool data and resources to produce the largest neuroimaging studies of BD ever conducted. The ENIGMA Bipolar Disorder Workin…
Angiogenic and/or pro-apoptotic factors are shed from brain cells via extracellular vesicles
2008
We set a three-cell type coculture system in which neurons and astrocytes synergistically induce brain capillary endothelial cells to form a monolayer with permeability properties resembling those of the physiological blood-brain barrier (BBB) (Schiera et al., 2003; Schiera et al., 2005). On the basis of immunofluorescence, scanner electron microscopy and western blot analyses, we also suggested that both astrocytes and neurons in culture shed extracellular vesicles that contain FGF-2 and VEGF, as well as beta1-integrin, a membrane protein that can be considered a marker of shedding (Schiera et al, 2007; Proia et al., 2008). In addition, it was already known that transformed glial cells (ol…
Zināšanas Vitgenšteina “Filosofiskajos pētījumos” un “Par drošticamību”
2017
Maģistra darba mērķis ir, aplūkojot Vitgenšteina zināšanu izpratni “Filozofisko pētījumu” periodā un darbā “Par drošticamību”, argumentēt par labu idejai, ka darbā “Par drošticamību” Vitgenšteins nenovēršas no savas iepriekšējās filozofijas izpratnes. Darbā tiek aizstāvēts uzskats, ka Vitgenšteins, pretēji noteiktu interpretētāju apgalvojumiem, arī darbā “Par drošticamību”, pievēršoties zināšanu problēmai, saglabā savas metodiskās nostādnes. Darbā izpētīta Vitgenšteina filozofijas metodes izpratne, aplūkots un salīdzināts zināšanu problēmas risinājums abos darbos, kritizētas interpretācijas, kuras aizstāv filozofijas izpratnes maiņas ideju Vitgenšteina filozofijā, kā arī šo interpretāciju v…