Search results for "THD"

Patterns matter: continuous Vs intermittent access to ethanol differently affects withdrawal behavioural phenotype and maternal care in female rats.

2014

Modeling voluntary ethanol consumption in female rats is crucial for gaining further insight in gender-related vulnerability to alcohol. Since ethanol effects depend not only on the amount consumed, but also on drinking pattern, this study aimed at assessing the influence of continuous and intermittent ethanol self-administration on peculiar aspects of female behavioural repertoire during withdrawal and relapse. Female rats undergoing a 15-week-long, 20% ethanol continuous or intermittent (3days/week) access, respectively named CARs and IARs, were tested for alcohol intake (gr/kg) and preference. During withdrawal we assessed: novelty and reward preference in novel object exploration and sa…

Sodium oxybate therapy for the treatment of alcohol withdrawal syndrome and the maintenance of alcohol abstinence

2017

Gamma-hydroxybutyrate (GHB or sodium oxybate) is both an exogenous and endogenous molecule with neuromodulator properties. In the United States, GHB is an approved drug for the treatment of narcolepsy and narcolepsy with cataplexy in adults. In some European Union countries, sodium oxybate is applied for the treatment of opioid and alcohol withdrawal.

The significance of perceived development opportunities in the context of retention : comparing ageing and younger nurses

2012

Perceived development opportunities and reward satisfaction as antecedents of nurses’ job withdrawal intentions

2016

Retention of nurses has received considerable attention in recent years due to the ageing population and the shortage of nurses. However, most of the studies have concentrated on either older nurses’ early retirement or younger nurses’ turnover intentions. This study analyses the antecedents of different forms of job withdrawal intentions with special reference to perceived development opportunities and reward satisfaction. A quantitative survey was conducted among nurses in one Finnish University hospital. A total of 510 nurses completed the questionnaire, representing a 54.4% response rate. The results demonstrated that job withdrawal intentions were relatively common and age-dependent am…

The joint effects of parenting styles and the child's temperamental characteristics in children's social-emotional development

2016

This research examined the joint effects of parenting and the temperamental characteristics of children on their social-emotional development during their early school years. Three studies, focusing on different aspects of social-emotional development as well as on different temperamental characteristics, were carried out. The first study investigated the extent to which mothers' and fathers' parenting styles differently impact their children's social-emotional development, based on the children's tendency to show signs of social withdrawal. The second study focused on the different impacts of parenting styles on children's emotional expression, depending on the children's temperament type.…

Investigation about selective harmonic elimination in unbalanced multilevel inverters

2022

In this paper 5 and 7 levels cascaded H-bridges inverters are considered, feeding by unequal dc voltage sources. The effect of these unbalancing operation is examined concerning harmonic analysis and total harmonic distortion of the output voltages. The system of equations, obtained by the expansion in the Fourier series of phase output voltage, is solved by applying a method of graphic solution that allows obtaining the switching angles able to eliminate the lower order harmonics.

Data from: Transanal hemorrhoidal dearterialization (THD) with Doppler arterial identification versus classic hemorrhoidectomy: a retrospective analy…

2019

Purpose: Despite the minimally invasive nature of transanal hemorrhoidal dearterialization (THD) with Doppler arterial identification procedures, hemorrhoidectomy is still considered the gold standard procedure for hemorrhoidal disease. However, the classical techniques of hemorrhoidectomy have a high rate of postoperative complications. The main purpose of this study is to demonstrate the efficacy and complications of these techniques used for grades II and III hemorrhoids. Methods: A retrospective (case-control) study was carried out from January 2009 to May 2014, and all patients undergoing surgical procedures for hemorrhoidal disease in two French clinics were considered. Application of…

Standardized Hemorrhagic Shock Induction Guided by Cerebral Oximetry and Extended Hemodynamic Monitoring in Pigs.

2019

Hemorrhagic shock ranks among the main reasons for severe injury-related death. The loss of circulatory volume and oxygen carriers can lead to an insufficient oxygen supply and irreversible organ failure. The brain exerts only limited compensation capacities and is particularly at high risk of severe hypoxic damage.This article demonstrates the reproducible induction of life-threatening hemorrhagic shock in a porcine model by means of calculated blood withdrawal. We titrate shock induction guided by near-infrared spectroscopy and extended hemodynamic monitoring to display systemic circulatory failure, as well as cerebral microcirculatory oxygen depletion. In comparison to similar models tha…

Blood alcohol concentration for monitoring ethanol treatment to prevent alcohol withdrawal in the intensive care unit.

2001

Abstract Objective. Alcohol withdrawal syndrome (AWS) is a serious complication during postoperative treatment in chronic alcoholics. Despite prophylactic treatment, AWS occurs in at least 25% of these patients after elective surgery. An established protocol for the prevention of AWS is ethanol administration. The aim of this study was to evaluate possible differences in ethanol dose and levels between successfully treated patients and those who developed AWS. Design. Prospective, observational study with retrospective post hoc analysis. Setting. Intensive care unit (ICU). Patients. Thirty-two alcohol-dependent patients undergoing elective or emergency surgery after trauma with postoperativ…

Transanal Hemorrhoidal Dearterialization With Doppler Arterial Identification Versus Classic Hemorrhoidectomy: A Retrospective Analysis of 270 Patien…

2019

Purpose: Despite the minimally invasive nature of transanal hemorrhoidal dearterialization (THD) with Doppler arterial identification procedures, hemorrhoidectomy is still considered the gold standard procedure for hemorrhoidal disease. However, the classical techniques of hemorrhoidectomy have a high rate of postoperative complications. The main purpose of this study is to demonstrate the efficacy and complications of these techniques used for grades II and III hemorrhoids.Methods: A retrospective (case-control) study was carried out from January 2009 to May 2014, and all patients undergoing surgical procedures for hemorrhoidal disease in two French clinics were considered. Application of …