Search results for "TIMIT"
showing 10 items of 150 documents
Lo Stato contemporaneo e la sua crisi
2011
Si tratta della crisi attuale dello Stato in riferimento agli ambiti della teoria del diritto, secondo la storia del diritto,del diritto costituzionale,del diritto amministrativo, del diritto internazionale, del diritto penale del diritto tributario.
Esperienze di attaccamento e competenza emotiva nei minori abusanti
2014
Le relazioni interpersonali consentono ai bambini di apprendere quale significato attribuire alle emozioni, nonché quali modalità socialmente accettabili utilizzare; tra le variabili in grado di spiegare il comportamento dei minori abusanti appaiono particolarmente significative la scarsa competenza emotiva e l’insicurezza del legame di attaccamento. La valutazione della storia personale e dell’Adult Attachment Interview di due utenti dell’Ufficio di Servizio Sociale per i Minorenni (USSM) di Palermo accusati di un reato sessuale ha permesso di evidenziare una mancanza di intimità nelle relazioni che viene disfunzionalmente compensata attraverso la condotta abusante. L’analisi dei due casi …
Antimitochondrial antibody -M2 positive autoimmune hepatitis during standard of care for chronic hepatitis C.
2012
The current standard of care (SoC) for chronic hepatitis C, i.e. the combination of a pegylated-interferon (PEG-IFN) with ribavirin (RBV), may activate underlying autoimmune conditions. Particularly, interferon (IFN) has been known to induce or exacerbate autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC) in hepatitis C virus patients. We describe a severe, acute-onset antimitochondrial antibody (AMA)-M2 positive AIH appearing during the last weeks of SoC in a woman with chronic hepatitis C and no previous history of autoimmunity, and resolving on protracted steroids. In this context, the relevance of the characterization of the immunoglobulin isotype of portal plasma cells for …
Il ruolo del bilancio sociale nelle università pubbliche italiane
2014
Le pouvoir royal (1814-1848). A la recherche du quatrième pouvoir ?
2021
This work sheds light on the representations of royal power that confronted each other until 1848 to fulfil the programme of reconciliation of the "two France" wanted by Louis XVIII. They are divided between the desire to return to the Ancien Régime and the attempt to renew the royal function. Opposed to the ultraroyalists, the supporters of this original path wished to consecrate liberal constitutionalism by resorting to an unexpected expedient, the power of the King, which had to be remodelled. As with Constant and Dunoyer, it was a question of creating a fourth power with its own essence and a new mission: to watch over the institutions. This regulating or preserving power produced a pas…
Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
2007
Two new series of inhibitors of tubulin polymerization based on the 2-amino-3-(3,4,5-trimethoxybenzoyl)benzo[b]thiophene molecular skeleton and its 3-amino positional isomer were synthesized and evaluated for antiproliferative activity, inhibition of tubulin polymerization, and cell cycle effects. Although many more 3-amino derivatives have been synthesized so far, the most promising compound in this series was 2-amino-6-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]thiophene, which inhibits cancer cell growth at subnanomolar concentrations and interacts strongly with tubulin by binding to the colchicine site.
Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-N,N-dimethylamino benzo[b]furan derivatives as inhibitors of tubulin polymeri…
2008
Molecules that target microtubules have an important role in the treatment of cancer. A new class of inhibitors of tubulin polymerization based on the 2-(3,4,5-trimethoxybenzoyl)-2-dimethylamino-benzo[b]furan molecular skeleton was synthesized and evaluated for antiproliferative activity, inhibition of tubulin polymerization, and cell cycle effects. The most promising compound in this series was 2-(3,4,5-trimethoxybenzoyl)-3-dimethylamino-6-methoxy-benzo[b]furan, which inhibits cancer cell growth at nanomolar concentrations and interacts strongly with tubulin by binding to the colchicine site.
Reconfiguration du modèle conjugal à l'heure de l'hyperconnectivité : TIC et territoires de l'intime
2014
Online devices are part of our daily lives, fundamentally changing our habits and practices,especially as regards relationships as well as interpersonal and social communication.In this doctoral research, the aim was to analyse the ways in which Information and CommunicationTechnologies (ICTs) have somehow ‘reshaped’ the traditional conjugal model.Indeed, more than just technical devices, ICTs are communicational and even ‘transitional’devices. They are means of strategies and issues within the couple and the family. Theseincreasingly nomadic technologies question the couple regarding its foundations. First ofall, the phenomenon of hyper connectivity (or ‘continuous connectivity’) creates a…
Novel method and instruments for the optimal techno-economic sizing of borehole heat exchangers
2021
El test de respuesta térmica (TRT) es ampliamente utilizado como método estándar para caracterizar las propiedades térmicas del terreno adyacente a un intercambiador de calor enterrado (BHE). Los métodos tradicionales para interpretar los resultados aplican soluciones analíticas o numéricas asumiendo que el terreno es infinito, homogéneo e isotrópico. Sin embargo, en realidad el subsuelo presenta generalmente una estructura estratificada y heterogénea, y por lo tanto las propiedades térmicas pueden variar sustancialmente con la profundidad. En este sentido y con la intención de resolver las limitaciones del TRT estándar, la presente tesis doctoral se centra en el desarrollo de métodos e ins…
Tehno-intimitāte mūsdienu Japānas sabiedrībā
2016
Japāna jau ilgu laiku ir zināma kā zeme, kurā tehnika ieņem nozīmīgu lomu sabiedrības ikdienā. Edo periodā meistari darināja karakuri mehāniskās lelles, kas tiek uzskatītas par robotu priekštečiem. Pēc Edo perioda modernizācijā un robotos Japānas sabiedrība saskatīja atbildi vairākām problēmām, gan ekonomiskās, gan sociālām. Mūsdienās roboti ir blakus cilvēkiem un lēnām kļūst par daļu no sabiedrības. Līdz kā tehnika sāk ieņemt jaunu lomu, sabiedrības attiecības ar to mainās. No utilitārim rīkiem izdzīvošanai, tehnika kļūst par draugu, kompanjonu, kas beigās noved pie tehno-intimitātes izveidošanās. Ar vārdu “intīms” parasti apraksta saikni starp cilvēkiem, bet mūsdienās tas tiek izmantots a…