Search results for "TLE"
showing 10 items of 2417 documents
Modeling evolution of the San Andreas Fault system in northern and central California
2012
[1] We present a three-dimensional finite element thermomechanical model idealizing the complex deformation processes associated with evolution of the San Andreas Fault system (SAFS) in northern and central California over the past 20 Myr. More specifically, we investigate the mechanisms responsible for the eastward (landward) migrationof the San Andreas plate boundary over time, a process thathas largely determined the evolution and present structure of SAFS. Two possible mechanisms had been previously suggested. One mechanism suggests that the Pacific plate first cools and captures uprising mantle in the slab window, subsequently causing accretion of the continental crustal blocks. An alt…
Dumb Animals: A Short History of Classical Logocentrism
2021
Among the most common and influential stereotypes of Greco-Roman literature is the idea that animals are ‘dumb’ (ἄλογα/muta), that is, mute and devoid of reason. In recent years, several explorations of what Stephen Newmyer has aptly called the ‘man alone of animals’ topos have pointed out that in asserting the privileged status of humans the ancients attached special importance to articulate language. Yet, most of these explorations have adopted a thematic rather than historical approach in an attempt to provide a comparative assessment of ancient and modern paradigms. In the present paper, I follow a historical line through the literary representations of animals as ‘dumb’, focusing on tw…
Pleasure and Knowledge in Aristotle's Rhetoric
2018
The paper focuses on a basic principle of Aristotle’s Rhetoric according to which the more a discourse is able to produce in the hearer a quick and pleasant learning, the more it will be persuasive. Starting from the numerous examples provided by Aristotle, the paper shows that this principle, which we can call Pleasure and Knowledge Principle (PKP), regards all the levels of a speech (inventio as well as elocutio, actio, and dispositio) and it is founded in Aristotle’s anthropology and epistemology. Thanks to this feature, PKP can be considered the common thread of the whole Rhetoric as well as a good starting point for a general reflection on the persuasive power of language and its role …
Urban Regionalisation Processes in Sicily: From the Theoretical Framework to the Local Dynamics
2021
This introductory chapter proposes a mainly theoretical reflection on the category of the urban, both as a spatial and social product and as an economic and political one, in territories marked by settlement transformation phenomena. In tracking this evolutionary path, this chapter addresses the huge thematic bibliog- raphy on the phenomena of urban regionalisation without any demand for systematic approach but pursuing the aim of tracing the geography of this on-going transition in Sicily.
Impact of Plastic Debris on the Gut Microbiota of Caretta caretta From Northwestern Adriatic Sea
2021
Plastic pollution is nowadays a relevant threat for the ecological balance in marine ecosystems. Small plastic debris (PD) can enter food webs through various marine organisms, with possible consequences on their physiology and health. The loggerhead sea turtle (Caretta caretta), widespread across the whole Mediterranean Sea, is a “flagship species,” useful as indicator of the general pollution level of marine ecosystems. Ingested PD accumulate in the final section of turtles’ digestive tract before excretion. During their transit and accumulation, PD also interact with the residing microbial community, with possible feedback consequences on the host’s health. To explore the possible relati…
Władze RP na uchodźstwie wobec sytuacji w Polsce w latach 1971–1975
2019
The article presents opinions and assessments o f the Polish authorities in exile (the president and the govemment) on the situation o f Poland in the first half of the 70s. The emigration authorities were absolutely against the inhuman actions during the December 1970 workers’ rebellion. The “Polish” London, lacking in information from the country, wrote about hundreds o f people killed and wounded. They were also pointing to the tragic economic situation o f Poland and the economic exploitation by the USSR. Emigration representatives o f the political elites idealised the attitude o f fellow citizens in Poland. In the opinion o f emigrants, the country remained in resistance to the impose…
Influence of the xyloadenosine analogue of 2?,5?-oligoriboadenylate on poly(A)-specific, 2?,5?-oligoriboadenylate degrading 2?,3?-exoribonuclease and…
1984
The homogeneous poly(A)-specific 2′,3′-exoribonuclease from calf thymus gland, which cleaves both 3′,5′-and 2′,5′-linked oligoriboadenylates, does not degrade (xyloA2'p)2 xyloA, the xylofuranosyladenosine analogue of the 2-5A core. This oligonucleotide, which is supposed to enter intact cells rapidly, was found to possess an increased stability and an enhanced antiherpesvirus activity compared to the natural (A2'p)2A (Eppstein, D. A., Barnett, J. W., Marsh, Y. V., Gosselin, G. and Imbach, J.-L. (1983) Nature 302, 723–724). The poly(A) anabolic enzyme, poly(A) polymerase (Mn2+-dependent), from the same source, which is initiated by (A3'p)2A and its higher oligomers, does not accept 2–5A core…
Covalently Binding of Bovine Serum Albumin to Unsaturated Poly(Globalide-Co-ε-Caprolactone) Nanoparticles by Thiol-Ene Reactions.
2019
When nanoparticles (NPs) are introduced to a biological fluid, different proteins (and other biomolecules) rapidly get adsorbed onto their surface, forming a protein corona capable of giving to the NPs a new "identity" and determine their biological fate. Protein-nanoparticle conjugation can be used in order to promote specific interactions between living systems and nanocarriers. Non-covalent conjugates are less stable and more susceptible to desorption in biological media, which makes the development of engineered nanoparticle surfaces by covalent attachment an interesting topic. In this work, the surface of poly(globalide-co-e-caprolactone) (PGlCL) nanoparticles containing double bonds i…
In situ forming hydrogels of hyaluronic acid and inulin derivatives for cartilage regeneration.
2014
An in situ forming hydrogel obtained by crosslinking of amino functionalized hyaluronic acid derivatives with divinylsulfone functionalized inulin (INU-DV) has been here designed and characterized. In particular two hyaluronic acid derivatives bearing respectively a pendant ethylenediamino (EDA) portion (HA-EDA) and both EDA and octadecyl pendant groups (HA-EDA-C18) were crosslinked through an azo-Michael reaction with INU-DV. Gelation time and consumption of DV portions have been evaluated on hydrogel obtained using HA-EDA and HA-EDA-C18 derivatives with a concentration of 3% w/v and a ratio 80/20 w/w respect to the crosslinker INU-DV. The presence of pendant C18 chains improves mechanical…
Influence of the polymerization step alone on oxygen affinity and cooperativity during production of hyperpolymers from native hemoglobins with cross…
1994
The aim of this study was to find out how the polymerization per se changes oxygen affinity (P50) and cooperativity (n50) of various soluble huge hyperpolymers prepared from native hemoglobins by crosslinking. Increase of cooperativity would be expected considering natural hemoglobin networks. Those hyperpolymers with molecular weights of some 10(6) g/mol are candidates for artificial oxygen-carrying blood additives rather than volume substitutes. Human and bovine hemoglobin reacted with several crosslinkers (2,5-diisothiocyanatobenzenesulfonate (DIBS); 4,4'-diisothiocyanatostilbene-2, 2'-disulfonate (DIDS); 1,3-butadiene diepoxide (BUDE); glutaraldehyde (GDA)) in concentrated (case 1) and …