Search results for "TOMS"
showing 10 items of 1058 documents
Competence and adherence in an acceptance and values-based intervention: Effects on treatment outcome and early changes in depression
2020
Abstract Background The present study investigated competence and adherence in an acceptance- and values-based intervention and their impact on the outcomes of treatment and early changes in depression. Method A total of 74 sessions delivered by novice therapists (n = 37) were rated for overall competence and adherence to treatment manual, as well as for process-specific components of acceptance and commitment therapy (ACT) using the ACT Adherence Scale (Plumb & Vilardaga, 2010). The relationships between (a) competence and adherence, (b) treatment outcome, and (c) early therapeutic changes among patients diagnosed with major depressive disorder (n = 37) were explored. Results Higher compet…
A psychological flexibility -based intervention for burnout : A randomized controlled trial
2020
A novel eight-week program based on Acceptance and Commitment Therapy (ACT) principles was created to alleviate burnout-related ill-being and to enhance well-being. This randomized controlled trial investigated the effectiveness of the program and explored whether changes in psychological flexibility mediated the results of the intervention. The program consisted of structured weekly face-to-face group meetings and daily practices provided via a website. Employees from varying professional backgrounds with burnout (mean age = 47 years, 79% female), who all received usual treatment, 1 were randomized into control (TAU, n = 80, receiving no other support) and ACT + TAU intervention (n = 88, r…
El papel del mindfulness y el descentramiento en la sintomatología depresiva y ansiosa
2016
ResumenLos síntomas depresivos y ansiosos tienen un claro impacto en el funcionamiento de las personas. Su aparición parece tener relación con la presencia de déficits en las capacidades metacognitivas. El entrenamiento en atención plena aumenta el insight metacognitivo a través de la capacidad de descentramiento. Por ello el objetivo de este estudio ha sido evaluar la relación entre la atención plena y el descentramiento con la sintomatología ansiosa y depresiva respectivamente. La muestra de este estudio está compuesta por 465 participantes y el contacto con ella se estableció a través de universidades y redes sociales. Los resultados revelaron que tanto la atención plena como la capacida…
Trajectories of stress biomarkers and anxious-depressive symptoms from pregnancy to postpartum period in women with a trauma history
2019
Background: Cross-sectional studies have found that a trauma history can be associated with anxious-depressive symptomatology and physiological stress dysregulation in pregnant women. Methods: This prospective study examines the trajectories of both anxiety and depressive symptoms and salivary cortisol and alpha-amylase biomarkers from women with (n = 42) and without (n = 59) a trauma history at (i) 38th week of gestation (T1), (ii) 48 hours after birth (T2), and (iii) three months after birth (T3). Results: The quantile regression model showed that trauma history was associated with higher cortisol levels at T1 and this difference was sustained along T2 and T3. Conversely, there were no si…
EHealth Interventions for People Suffering From Sleep Problems and Depressive Symptoms
2017
This chapter highlights qualitative findings from two field studies that focused on supporting people with sleeplessness (Study 1) and moderate depression (Study II). Both the studies were designed to examine the prospective impact of reminders and rehearsal on the effectiveness of web- based eHealth interventions. The interventions were incorporated with Acceptance and Commitment Therapy. In this chapter, qualitative findings are reported with an aim to highlight issues that are at times overlooked. Further, the findings are expected to help researchers better understand eHealth interventions for mental health care. Results from the two studies uncover interesting contrasts. While the part…
Correlates of depressive symptoms in transgender women initiating HIV treatment in Argentina
2021
Transgender women (TGW) experience high prevalence of depression worldwide.This study analyzed the prevalence and correlates of depressive symptoms among 61 HIV + TGW (age: M = 29.87 years, SD = 6....
An Internet-based program for depressive symptoms using human and automated support: a randomized controlled trial
2017
Adriana Mira,1 Juana Bretón-López,1,2 Azucena García-Palacios,1,2 Soledad Quero,1,2 Rosa María Baños,2,3 Cristina Botella1,2 1Department of Basic, Clinical Psychology and Psychobiology, Labpsitec, Universitat Jaume I, Castellón de la Plana, Spain; 2CIBER of Physiopathology of Obesity and Nutrition CIBERobn, CB06/03 Instituto de Salud Carlos III, Santiago de Compostela, Spain; 3Department of Personality, Evaluation and Psychological Treatment, Universidad de Valencia, Valencia, Spain Purpose: The purpose of this study was to analyze the efficacy of an Internet-based program for depressive symptoms using automated supp…
Exploring the Incorporation of a Positive Psychology Component in a Cognitive Behavioral Internet-Based Program for Depressive Symptoms. Results Thro…
2018
Traditionally, evidence-based treatments for depression have focused on negative symptoms. Different authors describe the need to include positive affect as a major target of treatment. Positive psychology aims to fill this gap. Reaching everyone in need is also important, and Internet-based interventions can help in this task. The present study is a secondary analysis derived from a randomized controlled trial aimed to test the efficacy of an Internet-based intervention for patients with depressive symptoms. This intervention consisted of an 8-module Internet-based program that combined four modules based on cognitive-behavioral therapy strategies and four modules based on positive psychol…
Eight-membered heterocycles with two heteroatoms in a 1,5-relationship of interest in medicinal chemistry
2020
Abstract This review deals with 1,5-diheterocines that exhibited biological properties and covers comprehensively the literature from 2007 to the end of February 2019. Among the six possible heterocyclic systems belonging to the eight-membered rings with two heteroatoms, N, O, and S, five had derivatives showing pharmacological activities: 1,5-diazocines, 1,5-oxazocines, 1,5-thiazocines, 1,5-dioxocins, and 1,5-dithiocins. Instead, literature reported no articles dealing with 1,5-oxathiocins of interest in medicinal chemistry. In addition to uncondensed derivatives, 1,5-diheterocines fused to five- and six-membered carbocycles or heterocycles are covered. Bridged 1,5-diheterocines are covere…
Synthesis, Stability and Relaxivity of TEEPO-Met: An Organic Radical as a Potential Tumour Targeting Contrast Agent for Magnetic Resonance Imaging
2018
Cancer is a widespread and life-threatening disease and its early-stage diagnosis is vital. One of the most effective, non-invasive tools in medical diagnostics is magnetic resonance imaging (MRI) with the aid of contrast agents. Contrast agents that are currently in clinical use contain metals, causing some restrictions in their use. Also, these contrast agents are mainly non-specific without any tissue targeting capabilities. Subsequently, the interest has notably increased in the research of organic, metal-free contrast agents. This study presents a new, stable organic radical, TEEPO-Met, where a radical moiety 2,2,6,6-tetraethylpiperidinoxide (TEEPO) is attached to an amino acid, methio…