Search results for "TOXICITY"

showing 10 items of 2261 documents

The role of metallothionein and selenium in metal detoxification in the liver of deep-sea fish from the NW Mediterranean Sea

2014

8 pages, 1 figure, 5 tables

Fish ProteinsMaleEnvironmental Engineeringchemistry.chemical_elementMetal toxicityZincBiologyMetal detoxificationMass Spectrometrychemistry.chemical_compoundSeleniumMediterranean seaMetals HeavyLactate dehydrogenaseDeep sea fishMediterranean SeaAnimalsEnvironmental ChemistryMetallothioneinMuscle SkeletalWaste Management and DisposalL-Lactate DehydrogenaseFishesPollutionMercury (element)ZincchemistryLiverSpainEnvironmental chemistryInactivation MetabolicAcetylcholinesteraseFemaleMetallothioneinDeep-sea fishBiomarkersWater Pollutants ChemicalSeleniumEnvironmental MonitoringPolarography
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Comparative study of the toxicity of molinate for freshwater organisms.

2003

Food ChainHealth Toxicology and MutagenesisDaphnia magnaZoologyBranchiopodaBiologyToxicologyAlgaeChlorophytaThiocarbamatesNannochloris oculataEcotoxicologyAnimalsEcologyHerbicidesGeneral MedicineAzepinesFeeding BehaviorPesticidebiology.organism_classificationPollutionCladoceraDaphniaToxicityCarbamatesWater Pollutants ChemicalBulletin of environmental contamination and toxicology
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Mycotoxins: Toxicology, Identification and Control

2021

The evaluation of the presence of mycotoxins in different matrices is achieved through different analytical tools (including quantitative or qualitative determinations) [...]

Food ChainManagement scienceComputer scienceHealth Toxicology and Mutagenesislcsh:RMEDLINElcsh:MedicineMycotoxinsToxicologyAnimal FeedRisk Assessmentchemistry.chemical_compoundFood chainn/aEditorialchemistryToxicity TestsFood MicrobiologyAnimalsHumansIdentification (biology)MycotoxinRisk assessmentIntroductory Journal ArticleToxins
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Simultaneous Separation of Antioxidants and Carbohydrates From Food Wastes Using Aqueous Biphasic Systems Formed by Cholinium-Derived Ionic Liquids

2019

project CICECO-Aveiro Institute of Materials, UID/CTM/50011/2019. Associate Laboratory for Green Chemistry-LAQV, FCT Ref. UID/QUI/50006/2019. POCI-01-0145-FEDER-016403. Investigator FCT project IF/00621/2015. Programa Mais Centro under project CENTRO-07-ST24-FEDER-002008. COMPETE: PEst-C/SAU/UI0709/2011. The food industry produces significant amounts of waste, many of them rich in valuable compounds that could be recovered and reused in the framework of circular economy. The development of sustainable and cost-effective technologies to recover these value added compounds will contribute to a significant decrease of the environmental footprint and economic burden of this industry sector. Acc…

Food industry02 engineering and technology010402 general chemistry01 natural sciencesionic liquidslcsh:Chemistrychemistry.chemical_compoundaqueous biphasic systemsPhase (matter)Organic chemistryMonosaccharidevalue added compoundsresource efficiencyBistriflimideOriginal Researchchemistry.chemical_classificationAqueous solutionbusiness.industryExtraction (chemistry)circular economytoxicitySDG 8 - Decent Work and Economic GrowthGeneral Chemistry021001 nanoscience & nanotechnology0104 chemical sciencesChemistryFood wastewaste valorizationchemistryfood wastelcsh:QD1-999Ionic liquid0210 nano-technologybusinessSDG 12 - Responsible Consumption and ProductionFrontiers in Chemistry
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Safety Assessment and Migration Tests

2018

This chapter outlines (i) the advances to reduce the uncertainty in nanomaterials (NMs) determination; (ii) the results from migration experiments conducted with nano-clay, nanosilver, and other nanomaterial-containing polymers; and (iii) the different established protocols for risk assessment that ensure consumer's safety. The text starts highlighting the need of an understanding of potential exposure via migration into food and a deeper knowledge of the interaction of NMs with food constituents and their effects upon ingestion. The chapter covers the ability of the analytical techniques utilized to detect nanoparticles per se in food simulants. In addition, the results of the application …

Food packagingFood packagingToxicitySafety assessmentMigration testEnvironmental scienceBiochemical engineeringDetection techniquesRegulationsNanomaterials
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Effect of commercial mineral-based additives on composting and compost quality.

2009

Abstract The effectiveness of two commercial additives meant to improve the composting process was studied in a laboratory-scale experiment. Improver A (sulphates and oxides of iron, magnesium, manganese, and zinc mixed with clay) and B (mixture of calcium hydroxide, peroxide, and oxide) were added to source-separated biowaste:peat mixture (1:1, v/v) in proportions recommended by the producers. The composting process ( T , emissions of CO 2 , NH 3 , and CH 4 ) and the quality of the compost (pH, conductivity, C/N ratio, water-soluble NH 4 –N and NO 3 –N, water- and NaOH-soluble low-weight carboxylic acids, nutrients, heavy metals and phytotoxicity to Lepidium sarivum ) were monitored during…

FormatesFormic acidNitrogenAmmonium nitrateInorganic chemistryCarboxylic Acidsengineering.materialGarbageLepidiumAcetic acidchemistry.chemical_compoundAmmoniaSoilCalcium peroxideMetals HeavyToxicity TestsSoil PollutantsWaste Management and DisposalEnvironmental Restoration and RemediationAcetic AcidMineralsCalcium hydroxideCompostElectric ConductivityTemperatureHydrogen-Ion ConcentrationCarbonQuaternary Ammonium CompoundschemistryengineeringPhytotoxicityNuclear chemistryWaste management (New York, N.Y.)
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Ammonium formate-Pd/C as a new reducing system for 1,2,4-oxadiazoles. Synthesis of guanidine derivatives and reductive rearrangement to quinazolin-4-…

2021

1,2,4-Oxadiazole is a heterocycle with wide reactivity and many useful applications. The reactive O-N bond is usually reduced using molecular hydrogen to obtain amidine derivatives. NH4CO2H-Pd/C is here demonstrated as a new system for the O-N reduction, allowing us to obtain differently substituted acylamidine, acylguanidine and diacylguanidine derivatives. The proposed system is also effective for the achievement of a reductive rearrangement of 5-(2′-aminophenyl)-1,2,4-oxadiazoles into 1-alkylquinazolin-4(1H)-ones. The alkaloid glycosine was also obtained with this method. The obtained compounds were preliminarily tested for their biological activity in terms of their cytotoxicity, induce…

Formatesquinazolin-4-onemedicine.disease_causeGuanidineschemistry.chemical_compoundBiology (General)CytotoxicityAmmonium formateSpectroscopyOxadiazolesMolecular StructureChemistryAlkaloidBiological activityGeneral MedicineComputer Science ApplicationsChemistryOxidation-ReductionPalladiumCell SurvivalQH301-705.5Dipeptidyl Peptidase 4chemistry.chemical_elementAntineoplastic AgentsreductionArticleCatalysisInorganic ChemistryAmidine4-oxadiazolereduction;Cell Line TumorDiabetes MellitusAmmonium formatemedicineHumansHypoglycemic AgentsReactivity (chemistry)Physical and Theoretical ChemistryMolecular BiologyQD1-999QuinazolinonesSettore MED/04 - Patologia GeneralediacylguanidineOrganic Chemistry124-oxadiazolealpha-GlucosidasesacylguanidineSettore CHIM/06 - Chimica OrganicapalladiumCombinatorial chemistryModels ChemicalA549 CellsOxidative stress
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The Important Role of the Nuclearity, Rigidity, and Solubility of Phosphane Ligands in the Biological Activity of Gold(I) Complexes

2018

A series of 4-ethynylaniline gold(I) complexes containing monophosphane (1,3,5-triaza-7-phosphaadamantane (pta; 2), 3,7-diacetyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane (3), and PR3 , with R=naphthyl (4), phenyl (5), and ethyl (6)) and diphosphane (bis(diphenylphosphino)acetylene (dppa; 7), trans-1,2-bis(diphenylphosphino)ethene (dppet; 8), 1,2-bis(diphenylphosphino)ethane (dppe; 9), and 1,3-bis(diphenylphosphino)propane (dppp; 10)) ligands have been synthesized and their efficiency against tumor cells evaluated. The cytotoxicity of complexes 2-10 was evaluated in human colorectal (HCT116) and ovarian (A2780) carcinoma as well as in normal human fibroblasts. All the complexes showed a hi…

FosfinaMolecular ConformationOrCrystal structureCrystallography X-RayLigandsMedicinal chemistry01 natural scienceskultachemistry.chemical_compoundCoordination ComplexesDiphosphaneSolubilityCytotoxicityta116bcl-2-Associated X ProteinMembrane Potential Mitochondrialbioaktiiviset yhdisteetBiological activitybiological activity of gold(I) complexesAcetyleneProto-Oncogene Proteins c-bcl-2rigidityCompostos d'ornuclearityPhosphineCell SurvivalPhosphinesAntineoplastic Agentsphosphane ligands010402 general chemistryCatalysisCell LineStructure-Activity RelationshipMoleculeHumans010405 organic chemistrysolubilityOrganic ChemistryGeneral ChemistrykompleksiyhdisteetHCT116 Cells0104 chemical sciencesLligandschemistryQuantum TheoryGoldNonaneReactive Oxygen SpeciesGold compoundsChemistry: A European Journal
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Lethal toxicity of Lindane on a teleost fish,Anguilla anguillafrom albufera lake (Spain): Hardness and temperature effects

1988

This paper reports the results of toxicity tests conducted using Anguilla anguilla under three different water temperature (15, 22 and 29 degrees C) and two hardness regimes (250 and greater than 600 ppm CaCO3). The 96-h LC50 increased in the experimental medium (p less than 0.05) by an order of magnitude from 0.32 to 0.45 mg/L between 15 and 29 degrees C. However in the natural medium it is similar (p greater than 0.05) (0.54 to 0.55 mg/L) for these same temperatures. The toxicity of Lindane on eels increased when the water hardness decreased. The 24, 48, 72 and 96-h LC50 for this fish in both media is less at 15 degrees C (96-h LC50 = 0.32 and 0.55 mg/L) than at 29 degrees C (96-h LC50 = …

Fresh WaterBiologyMedian lethal doseLethal Dose 50chemistry.chemical_compoundAnimal scienceAnimalsWater PollutantsEcologyTemperatureWaterGeneral MedicinePesticideAnguillaPollutionchemistryFresh waterSpainWater temperatureToxicityFish <Actinopterygii>SeawaterLindaneHexachlorocyclohexaneWater Pollutants ChemicalFood ScienceJournal of Environmental Science and Health, Part B
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Fructose-1,6-Bisphosphate Protects Hippocampal Rat Slices from NMDA Excitotoxicity

2019

Effects of fructose 1,6-bisphosphate (F-1,6-P2) towards N-methyl-d-aspartate NMDA excitotoxicity were evaluated in rat organotypic hippocampal brain slice cultures (OHSC) challenged for 3 h with 30 &mu

Fructose 16-bisphosphateExcitotoxicityFructose-bisphosphate aldolaseorganotypic hippocampal brainslice culturesmedicine.disease_causeHippocampuslcsh:Chemistrychemistry.chemical_compoundenergymetabolismFructose-Bisphosphate Aldolaseenergy metabolismfructose-16-bisphosphatelcsh:QH301-705.5Spectroscopy<i>N</i>-methyl-<span style="font-variant: small-caps">d</span>-aspartatebiologyChemistryorganotypic hippocampal brain slice culturesGlyceraldehyde-3-Phosphate DehydrogenasesGeneral MedicineComputer Science ApplicationsFructose-BisphosphataseNeuroprotective AgentsNMDA receptorexcitotoxicityPhosphofructokinaseN-methyl-d-aspartatemedicine.medical_specialtyN-MethylaspartateFructose 16-bisphosphataseCatalysisArticleInorganic ChemistryNecrosisInternal medicinemitochondrial dysfunctionmedicineAnimalsPhysical and Theoretical ChemistryRats WistarMolecular BiologySettore BIO/10 - BIOCHIMICAOrganic ChemistryAldolase AMetabolismPurine NucleosidesRatsEndocrinologylcsh:Biology (General)lcsh:QD1-999Phosphofructokinases6-bisphosphatebiology.proteinfructose-1; 6-bisphosphate; N-methyl-d-aspartate; excitotoxicity; energymetabolism; mitochondrial dysfunction; organotypic hippocampal brainslice culturesfructose-1
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