Search results for "TSK"
showing 10 items of 296 documents
Festschrift zur Feier des 50 jährigen Bestehens des ersten Dorpatschen Lehrer-Seminars am 7. August 1878
1878
Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers.
2012
Background: Accurate outcome prediction in neuroblastoma, which is necessary to enable the optimal choice of risk-related therapy, remains a challenge. To improve neuroblastoma patient stratification, this study aimed to identify prognostic tumor DNA methylation biomarkers.Results: To identify genes silenced by promoter methylation, we first applied two independent genome-wide methylation screening methodologies to eight neuroblastoma cell lines. Specifically, we used re-expression profiling upon 5-aza-2'-deoxycytidine (DAC) treatment and massively parallel sequencing after capturing with a methyl-CpG-binding domain (MBD-seq). Putative methylation markers were selected from DAC-upregulated …
Vortrag über den Entwurf einer Centralschule für Handel und Gewerbe im Riga, gehalten am 19. Februar 1859 im Locale des Rigaschen Börsen-Comité's
1859
Īso un garo patskaņu diferencēšana 1. klases skolēniem ar fonētiski fonemātiskiem traucējumiem
2021
Andras Alksnes diplomdarbs logopēdijā „Īso un garo patskaņu diferencēšana 1.klases skolēniem ar fonētiski fonemātiskiem traucējumiem” izstrādāts Dr. paed. profesores Sarmītes Tūbeles vadībā. Diplomdarba mērķis ir pētīt un analizēt zinātnisko literatūru un veikt koriģējoši attīstošo darbību īso un garo patskaņu diferencēšanā 1. klases skolēniem ar fonētiski fonemātiskiem traucējumiem. Teorētiskajā daļā pētīts 1. klases skolēnu raksturojums veselumā, analizēta un apkopota zinātniskā literatūra par fonētiski fonemātiskajiem traucējumiem, fonemātisko uztveri un īso un garo patskaņu nozīmi latviešu literārajā valodā. Praktiskajā daļā veikta skolēnu logopēdiskā izpēte, izvēlēti atbilstoši koriģēj…
A contra-esperanza
2007
Per una buona psicoanalisi dell’arte: Vygostskij e il Mosè di Freud
2012
The aim of this article is to show that Vygotskijan and Freudian positions on the psychological analysis of art move from a similar conception of art and of human mind. To demonstrate our thesis we have substantially used two works: Vygostkij’s Psychology of art and Freud’s Moses of Michelangelo. We consider that, in spite of the critic that Vygostkij makes against the psychoanalytic approach to the products of art, probably for historic reasons, the importance that he gives to the notion of form, of social context and of conscious factors in artistic creations is the same that Freud gives in his applied psychoanalysis, and this is clear in the essay on Moses. In particular, if we concentra…
Anisotropic Navier Kirchhoff problems with convection and Laplacian dependence
2022
We consider the Navier problem-Delta(2)(k,p)u(x)=f(x,u(x), del u(x), Delta u(x)) in Omega, u vertical bar(partial derivative Omega) =Delta u vertical bar(partial derivative Omega) = 0,driven by the sign-changing (degenerate) Kirchhoff type p(x)-biharmonic operator, and involving a (del u, Delta u)-dependent nonlinearity f. We prove the existence of solutions, in weak sense, defining an appropriate Nemitsky map for the nonlinearity. Then, the Brouwer fixed point theorem assessed for a Galerkin basis of the Banach space W-2,W-p(x)(Omega)boolean AND W-0(1,p(x))(Omega) leads to the existence result. The case of nondegenerate Kirchhoff type p(x)-biharmonic operator is also considered with respec…
Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics stud…
2008
Contains fulltext : 71374.pdf (Publisher’s version ) (Closed access) Attention-deficit/hyperactivity disorder (ADHD) is typically characterized by inattention, excessive motor activity, impulsivity, and distractibility. Individuals with ADHD have significant impairment in family and peer relations, academic functioning, and show high co-morbidity with a wide range of psychiatric disorders including oppositional defiant disorder (ODD), conduct disorder (CD), anxiety disorder, depression, substance abuse, and pervasive developmental disorder (PDD). Family studies suggest that ADHD + CD represents a specific subtype of the ADHD disorder with familial risk factors only partly overlapping with t…
Meta-analysis of genome-wide linkage scans of attention deficit hyperactivity disorder
2008
Contains fulltext : 69243.pdf (Publisher’s version ) (Closed access) Genetic contribution to the development of attention deficit hyperactivity disorder (ADHD) is well established. Seven independent genome-wide linkage scans have been performed to map loci that increase the risk for ADHD. Although significant linkage signals were identified in some of the studies, there has been limited replications between the various independent datasets. The current study gathered the results from all seven of the ADHD linkage scans and performed a Genome Scan Meta Analysis (GSMA) to identify the genomic region with most consistent linkage evidence across the studies. Genome-wide significant linkage (P(S…
No association between two polymorphisms of the serotonin transporter gene and combined type attention deficit hyperactivity disorder.
2008
Contains fulltext : 71091.pdf (Publisher’s version ) (Closed access) Several independent studies have reported association between serotonin transporter gene (SLC6A4) polymorphisms and attention deficit hyperactivity disorder (ADHD). Five studies found evidence for association between the long-allele of a 44-bp insertion/deletion polymorphism (5-HTTLPR) and ADHD. Another two studies corroborated this finding while a further six studies did not find such an association. For a second polymorphism within the gene, a variable number tandem repeat (VNTR) within intron 2, one study demonstrated that the 12/12 genotype was significantly less frequent in ADHD cases compared to controls, while a sec…