Search results for "Tassi"
showing 10 items of 997 documents
In vivo hypotensive activity ofPistacia lentiscus L
1988
The present studies were undertaken to explain the mechanism of action of the hypothesive effect of Pistacia lentiscus L. aqueous extract. The potassium, calcium and magnesium content of the aqueous extract was determined and synthetic mixtures of salts evaluated in rats. The urinary excretion volume and the sodium and potassium concentrations in urine were also determined. In an effort to explain the effects of the extract, in vivo pharmacological experiments were conducted.
Efecto in vitro de la adición de resinas de intercambio iónico sobre la biodisponibilidad de electrolitos en fórmulas de nutrición enteral artificial
2008
The in vitro effect of the addition of ion exchange resins on the bioavailability of electrolytes in artificial enteral feeding formulas Objective: To determine in vitro free ion concentration in three standard artificial enteral feeding formulas following the addition of ion exchange resins. Method: Three standard types of AEF were chosen: Osmolite HN®, Nutrison Standard® and Isosource Standard®. The ion exchange resins used were: Sodium Polystyrene Sulfonate and Calcium Polystyrene Sulfonate. 100 ml of AEF were mixed in a beaker with 1.5 g or 3 g of ion exchange resins for 48 hours at 37oC. Subsequently, the samples were precipitated and the supernatant obtained was used for determining t…
Über den Chemismus von Zustandsänderungen des Aktomyosins
1950
(1) By means of a simple method the conditions were investigated for contraction and relaxation of actomyosin (AM) under the influence of potassium, magnesium, and calcium ions, of adenosintriphosphate (ATP) or muscle-adenylic-acid and phosphocreatin.
Die diuretische Wirkung von Oxytocin beim Hund
1959
The influence of a synthetic oxytocin preparation and of prednisolone hemisuccinate on the renal excretions of water, sodium, potassium and chloride and on the clearance of endogenous true creatinine was studied in 18 dogs anesthetized with hexobarbital and barbital. The animals were deprived of food and water for 12 hours before the experiments.
Action of tertiary phenylalkylamines on cardiac transient outward current from outside the cell membrane.
1996
The effects of the phenylalkylamines verapamil (V), gallopamil (G), and devapamil (D) and their corresponding quaternary derivatives on the transient outward current (Ito) were examined in rat ventricular cardiomyocytes using the whole-cell patch-clamp technique. The question was addressed, whether phenylalkylamines act on Ito from the inside or the outside or from both sides of the cell membrane. To this end, the myocytes were either superfused extracellularly or perfused intracellularly with drug-containing solutions. In addition, the effects of verapamil were investigated at different pH-values. V, G, and D (30 microM each), applied extracellularly, reduced the steady state current of It…
Intestinal transport in constipation and diarrhoea.
1988
Approximatively 10 liters of fluid enter the gastrointestinal tract with food and endogenous secretions, and only less than 100 ml or 1% leave it with the faeces. Minor changes of this equilibrium in the intestinal transport may cause diarrhoea or constipation. Functions of small and large intestine differ markedly in transport of electrolytes and water. The relatively leaky epithelium of the small intestine allows for rapid equilibrium of osmolality in both directions while the tight epithelium of the colon preserves electrolytes and water once they have been absorbed. It may compensate secretory diarrhoea of the small intestine for instance caused by bacterial toxins to a certain degree u…
Determination of Phenylephrine Hydrochloride by Flow Injection Analysis with Chemiluminescence Detection
2001
Abstract A new method is proposed for the determination of phenylephrine hydrochloride by flow injection analysis with direct chemiluminescence detection. The method is based on the oxidation of the drug by potassium permanganate in sulfuric acid medium at 80°C. The calibration graph is linear over the range 0.03–8 ppm phenylephrine hydrochloride, with a relative standard deviation (n = 51, 0.5 ppm) of 1.1% and sample throughput of 134/h. The influence of 38 different foreign compounds was tested, and the method was applied to the determination of phenylephrine hydrochloride in 8 different pharmaceutical formulations.
Die Wirkung von Ouabain auf die Elimination von Noradrenalin aus der Perfusionsfl�ssigkeit des isolierten Kaninchenherzens
1966
Isolated rabbit hearts were perfused with Tyrode solution containing 10 ng/ml (-)-noradrenaline for 20 min. The uptake by the heart of noradrenaline was calculated by estimating the percentage of amine removed from the perfusion fluid during a single passage through the heart. Previous experiments have shown that the amount of noradrenaline removed from the perfusion fluid corresponds well to the amount retained by the heart. In control experiments, the mean removal (elimination) of noradrenaline was 50±1.7% of the amount infused as measured biologically and 46±2.2% as measured fluorimetrically. Ouabain was added to the perfusion fluid at concentrations ranging from 2.74·10−7 to 2.0·10−6 mo…
Red blood cell sodium and potassium after hydrochlorothiazide.
1981
In six of seven healthy males 6 days of hydrochlorothiazide (HCT), 50 mg twice daily, without potassium supplements resulted in a rise in red blood cell (RBC) sodium concentration. Serum potassium concentration fell in all subjects. Four days after discontinuing HCT, intracellular sodium and extracellular potassium concentrations had normalized. Throughout the evaluation period the course of mean relative intracellular sodium was almost a mirror image of mean relative extracellular potassium. Thus, either the decline of serum potassium or of HCT (because of its inhibitory effect on Na-K-ATPase activity) might have diminished Na-K-ATPase–dependent active RBC sodium efflux with a resultant ri…
Effect of a "therapeutic" concentration of digitoxigenine on myocardial potassium and sodium content in Ca-poor media.
1972
The effect of 3·10−7 g/ml digitoxigenine on cellular K and Na concentrations, [K]i and [Na]i, water content, extracellular space, and contractile force was investigated in isolated electrically stimulated left guinea-pig auricles at reduced extracellular Ca concentration (0.45 mM). Digitoxigenine, which increased contractile force without producing arrhythmias or contractures, decreased [K]i and enhanced [Na]i. Water content and extracellular space remained unchanged. It is concluded that digitoxigenine can decrease myocardial [K]i and increase [Na]i even in “therapeutic” concentrations, provided that the experiments are performed in Ca-poor media.