Search results for "Technique"

showing 10 items of 5596 documents

Not only flint: Levallois on quartzite and limestone at Abrigo de la Quebrada (Valencia, Spain): Implications for neandertal Behavior

2016

This paper investigates the application of the Levallois technique to the knapping of nonflint raw materials (limestone and quartzite) in the upper levels of the Abrigo de la Quebrada rockshelter (Chelva, Valencia, Spain). Besides highlighting the significant flexibility that characterized Neandertal behavior, such an application is of singular interest because goodquality flint—lacking fissures and impurities and presenting a compact and homogeneous texture—is abundant in the site’s immediate vicinity. In other assemblages, the scarcity or poor quality of flint often suffices to explain the recourse to alternatives, but in these Quebrada levels raw material choice must be primarily determi…

010506 paleontologyHearthLevalloisLevallois technique01 natural sciencesPoor qualityLithic technologyArts and Humanities (miscellaneous)Middle PaleolithicMiddle Palaeolithic0601 history and archaeology:HISTORIA [UNESCO]Lithic technologyValencia0105 earth and related environmental sciencesUNESCO::HISTORIA060102 archaeologybiologyKnappingNeandertal behaviorLithic technology Levallois limestone quartzite Middle Paleolithic Neandertal behavior Iberian Peninsula06 humanities and the artsLimestonebiology.organism_classificationArchaeologyQuartziteHomogeneousAnthropologyGeologyIberian Peninsula
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L’étude archéologique des mortiers de chaux médiévaux : vers une meilleure compréhension des gestes du maçon

2020

International audience; Ces dernières décennies, l’étude des mortiers archéologiques, en particulier médiévaux, a connu un essor considérable en lien étroit avec celui de l’archéologie du bâti. Matériaux composites, possédant à la fois une forte identité géologique et un caractère anthropique certain, les mortiers sont considérés comme étant des marqueurs chronologiques potentiels pouvant aider à la compréhension de l’évolution d’un bâtiment. Mais, au-delà des problèmes de chronologie, l’étude du mortier de chaux, qui représente près de la moitié du volume d’une maçonnerie, a permis également de progresser sur la connaissance de toute la chaîne opératoire associée. Ainsi, du four à chaux au…

010506 paleontologyremploi[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and Prehistory060102 archaeology[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistorygisementarchéologie médiévalechantierMortier de chaux06 humanities and the artstechnique01 natural sciences[SHS]Humanities and Social SciencesArchaeologymatériautransportterrainextractionpatrimoine0601 history and archaeology[SHS] Humanities and Social Sciencesexpérimentation0105 earth and related environmental sciencesbâti
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Lowering histamine formation in a red Ribera del Duero wine (Spain) by using an indigenous O. oeni strain as a malolactic starter

2016

This study demonstrates for the first time that a non-commercial selected autochthonous O. oeni strain has been used to conduct malolactic fermentation (MLF) while lowering histamine formation in the same winery. Lactic acid bacteria (LAB) were isolated from 13 vats before and after spontaneous MLF at the Pago de Carraovejas winery from the Ribera del Duero region (Spain). Only O. oeni were present, typed and characterized, and both histamine producer and non-producers existed. From the non-producers, one strain was selected to become a starter according to its genetic profile, prevalence in the different wines in the winery, resistance to alcoholic degree, resistance to high polyphenolic c…

0106 biological sciences0301 basic medicine030106 microbiologyMalatesWine01 natural sciencesMicrobiology03 medical and health scienceschemistry.chemical_compoundStarterMalate DehydrogenaseRNA Ribosomal 16S010608 biotechnologyMalolactic fermentationLactic AcidFood scienceOenococcusWinebiologyStrain (chemistry)food and beveragesGeneral Medicinebiology.organism_classificationWineryRandom Amplified Polymorphic DNA TechniqueLactic acidchemistrySpainFermentationFood MicrobiologyHistamineBacteriaHistamineFood ScienceInternational Journal of Food Microbiology
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Recombinant laccase from Pediococcus acidilactici CECT 5930 with ability to degrade tyramine

2017

Biogenic amines degradation by bacterial laccases is little known, so we have cloned and heterologously expressed, in E. coli, a new laccase from Pediococcus acidilactici CECT 5930 (Lpa5930), a lactic acid bacterium commonly found in foods able to degrade tyramine. The recombinant enzyme has been characterized by physical and biochemical assays. Here we report the optimization of expression and purification procedures of this laccase. DNA encoding sequence of laccase from P. acidilactici was amplified by PCR and cloned into the expression plasmid pET28a for induction by isopropyl-β-D-thiogalactoipyranoside. Protein expression was performed in E. coli BL21(DE3) harboring pGro7 plasmid expres…

0106 biological sciences0301 basic medicineArabinoseMolecular biologylcsh:MedicineLaccasesBiochemistryBiotecnologia01 natural sciencesSubstrate Specificitylaw.inventionDatabase and Informatics Methodschemistry.chemical_compoundlawRecombinant Protein PurificationCloning MolecularAmineslcsh:Sciencechemistry.chemical_classificationMultidisciplinaryABTSbiologyOrganic CompoundsTemperatureHydrogen-Ion ConcentrationTyramineRecombinant ProteinsEnzymesChemistryRecombination-Based AssayBiochemistryPhysical SciencesRecombinant DNAElectrophoresis Polyacrylamide GelOxidation-ReductionSequence AnalysisResearch ArticleProtein PurificationBioinformaticsTyramineLibrary ScreeningDNA constructionResearch and Analysis Methods03 medical and health sciencesBacterial ProteinsSequence Motif Analysis010608 biotechnologyAmino Acid SequenceBenzothiazolesPediococcus acidilacticiLaccaseMolecular Biology Assays and Analysis TechniquesBase SequenceMolecular massLaccaseOrganic Chemistrylcsh:RChemical CompoundsBiology and Life SciencesProteinsPediococcus acidilacticiSequence Analysis DNAbiology.organism_classificationMolecular biology techniques030104 developmental biologyEnzymechemistryPlasmid ConstructionEnzymologySpectrophotometry Ultravioletlcsh:QSulfonic AcidsEnzimsProteïnesPurification TechniquesPLOS ONE
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Ocean acidification at a coastal CO2 vent induces expression of stress-related transcripts and transposable elements in the sea anemone Anemonia viri…

2019

Published version, available at: https://doi.org/10.1371/journal.pone.0210358 Ocean acidification threatens to disrupt interactions between organisms throughout marine ecosystems. The diversity of reef-building organisms decreases as seawater CO2 increases along natural gradients, yet soft-bodied animals, such as sea anemones, are often resilient. We sequenced the polyA-enriched transcriptome of adult sea anemone Anemonia viridis and its dinoflagellate symbiont sampled along a natural CO2 gradient in Italy to assess stress levels in these organisms. We found that about 1.4% of the anemone transcripts, but only ~0.5% of the Symbiodinium sp. transcripts were differentially expressed. Processe…

0106 biological sciences0301 basic medicineAtmospheric ScienceMolecular biologyMarine and Aquatic SciencesGene ExpressionRetrotransposonSea anemone01 natural sciencesAnemoniaSequencing techniquesMobile Genetic ElementsMultidisciplinarybiologyQREukaryotaOcean acidificationAnemoneRNA sequencingGenomicsChemistryRetrotransposonsPhysical SciencesMedicineTranscriptome AnalysisResearch ArticleScienceZoology010603 evolutionary biology03 medical and health sciencesGreenhouse GasesCnidariaGenetic ElementsSea WaterGeneticsVDP::Matematikk og Naturvitenskap: 400::Basale biofag: 470Environmental ChemistryAnimalsMarine ecosystemBiology and life sciencesEcology and Environmental SciencesDinoflagellateChemical CompoundsOrganismsTransposable ElementsCorrectionAquatic EnvironmentsComputational BiologyCarbon Dioxidebiology.organism_classificationGenome AnalysisMarine EnvironmentsInvertebratesVDP::Mathematics and natural science: 400::Basic biosciences: 470Research and analysis methods:Genetikk og genomikk: 474 VDP::Marinbiologi:497 VDP::Økologi:488 [VDP]030104 developmental biologySea AnemonesMolecular biology techniquesAtmospheric ChemistryEarth SciencesSeawater
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Interaction Between ABA Signaling and Copper Homeostasis inArabidopsis thaliana

2016

ABA is involved in plant responses to non-optimal environmental conditions, including nutrient availability. Since copper (Cu) is a very important micronutrient, unraveling how ABA affects Cu uptake and distribution is relevant to ensure adequate Cu nutrition in plants subjected to stress conditions. Inversely, knowledge about how the plant nutritional status can interfere with ABA biosynthesis and signaling mechanisms is necessary to optimize stress tolerance in horticultural crops. Here the reciprocal influence between ABA and Cu content was addressed by using knockout mutants and overexpressing transgenic plants of high affinity plasma membrane Cu transporters (pmCOPT) with altered Cu up…

0106 biological sciences0301 basic medicineBiologiaTranscription GeneticPhysiologyMutantArabidopsisPlant ScienceGenetically modified cropsSodium ChlorideGenes PlantPlant Roots01 natural sciencesGene Knockout Techniques03 medical and health scienceschemistry.chemical_compoundGene Expression Regulation PlantStress PhysiologicalArabidopsisHomeostasisArabidopsis thalianaPlantes Cèl·lules i teixitsAbscisic acidTranscription factorbiologyArabidopsis ProteinsMembrane transport proteinorganic chemicalsfungiMembrane Transport Proteinsfood and beveragesCell BiologyGeneral Medicinebiology.organism_classificationCell biologyOxidative StressPhenotype030104 developmental biologychemistryMutationbiology.proteinSignal transductionCopperAbscisic AcidSignal Transduction010606 plant biology & botanyPlant and Cell Physiology
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An SNP-based saturated genetic map and QTL analysis of fruit-related traits in Zucchini using Genotyping-by-sequencing

2016

[EN] Background: Cucurbita pepo is a cucurbit with growing economic importance worldwide. Zucchini morphotype is the most important within this highly variable species. Recently, transcriptome and Simple Sequence Repeat (SSR)- and Single Nucleotide Polymorphism (SNP)-based medium density maps have been reported, however further genomic tools are needed for efficient molecular breeding in the species. Our objective is to combine currently available complete transcriptomes and the Zucchini genome sequence with high throughput genotyping methods, mapping population development and extensive phenotyping to facilitate the advance of genomic research in this species. Results: We report the Genoty…

0106 biological sciences0301 basic medicineCartographyCandidate geneGenotyping TechniquesPopulationQuantitative Trait LociGenomicsSingle-nucleotide polymorphismFlowersBiologyQuantitative trait locusGBS01 natural sciencesPolymorphism Single NucleotideCandidate genes03 medical and health sciencesCucurbitaGeneticsGens MapatgeeducationGenotyping TechniquesGeneticsMolecular breedingWhole genome sequencingeducation.field_of_studyPigmentationChromosome MappingRILfood and beveragesGenomicsCucurbita pepoGENETICAGenòmica030104 developmental biologyPhenotypePhenotypingFruitSequence Analysis010606 plant biology & botanyBiotechnologyResearch Article
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Microspore Embryogenesis Through Anther Culture in Citrus clementina Hort. ex Tan.

2016

Anther culture is a biotechnological method that allows to obtain, in one step, homozygous plants, very important to plant breeding, due to their numerous applications in mutation research, selection, genome sequencing, genetic analysis, and transformation. To induce the microspores, i.e., the immature male gametes, to switch from the normal gametophytic pathway to the sporophytic one, it is necessary to submit them to a type of stress, such as high or low temperature, starvation, or magnetic field. Stress can be applied to the donor plants and/or the fl oral buds or the anthers or the isolated microspores, before or during the culture. In this chapter, the protocol to induce gametic embryo…

0106 biological sciences0301 basic medicineClementineAnther cultureCitruStamenMicrospore embryogenesiPlant DevelopmentGerminationBreedingHaploidyBiologymedicine.disease_cause01 natural sciencesGenetic analysis03 medical and health sciencesMicrosporePollenBotanyGeneticsmedicinePlant breedingCultivarMolecular BiologyPlant Somatic Embryogenesis TechniqueSomatic embryogenesifungiEmbryogenesisGametic embryogenesifood and beveragesSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeTransformation (genetics)030104 developmental biologyIsolated microspore cultureDoubled haploidPollenTissue Culture TechniqueGenome Plant010606 plant biology & botany
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Comparative Mitogenomics of Leeches (Annelida: Clitellata): Genome Conservation and Placobdella-Specific trnD Gene Duplication.

2015

Mitochondrial DNA sequences, often in combination with nuclear markers and morphological data, are frequently used to unravel the phylogenetic relationships, population dynamics and biogeographic histories of a plethora of organisms. The information provided by examining complete mitochondrial genomes also enables investigation of other evolutionary events such as gene rearrangements, gene duplication and gene loss. Despite efforts to generate information to represent most of the currently recognized groups, some taxa are underrepresented in mitochondrial genomic databases. One such group is leeches (Annelida: Hirudinea: Clitellata). Herein, we expand our knowledge concerning leech mitochon…

0106 biological sciences0301 basic medicineClitellatalcsh:MedicineBiochemistry01 natural sciencesGenomeDatabase and Informatics MethodsRNA TransferGene DuplicationGene OrderInvertebrate GenomicsGene duplicationAnnelidslcsh:SciencePhylogenyEnergy-Producing OrganellesData ManagementGeneticseducation.field_of_studyMultidisciplinaryPhylogenetic treePhylogenetic AnalysisGenomicsGenomic DatabasesMitochondriaNucleic acidsPhylogeneticsGenes MitochondrialPlacobdella parasiticaCellular Structures and OrganellesTransfer RNAResearch ArticleComputer and Information SciencesMitochondrial DNAPopulationBioenergeticsBiologyResearch and Analysis Methods010603 evolutionary biologyEvolution MolecularOpen Reading Frames03 medical and health sciencesPhylogeneticsLeechesGeneticsAnimalsEvolutionary Systematics14. Life underwaterCodonMolecular Biology TechniquesNon-coding RNAeducationMolecular BiologyTaxonomyMolecular Biology Assays and Analysis TechniquesEvolutionary Biologylcsh:ROrganismsBiology and Life SciencesComputational BiologyCell BiologyGenome Analysisbiology.organism_classificationInvertebratesBiological Databases030104 developmental biologyAnimal GenomicsGenome MitochondrialRNAlcsh:QPLoS ONE
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Lipid Nanoparticles as Potential Gene Therapeutic Delivery Systems for Oral Administration.

2017

Background Gene therapy has experimented an increasing attention in the last decades, due to its enormous potential applications in the medical field. It can be defined as the use of genes or genetic material (DNA, RNA, oligonucleotides) to treat or prevent a disease state, generally a geneticbased one. Application Other applications, like treating viral, bacterial or parasite infections or development of vaccines are gaining also interest. Efficient gene therapy is mainly dependent on the ability of the highly labile genetic material to reach the therapeutic target. For this purpose, different delivery systems have been designed and extensively investigated. Nanoparticles offer a broad ran…

0106 biological sciences0301 basic medicineGenetic enhancementAdministration OralComputational biologyBiologyGene deliveryPharmacology01 natural sciences03 medical and health sciencesDrug Delivery SystemsOral administration010608 biotechnologyNucleic AcidsDrug DiscoverySolid lipid nanoparticleGeneticsOral routeAnimalsHumansParasite InfectionsMolecular BiologyGeneGenetics (clinical)Drug CarriersGene Transfer TechniquesGenetic TherapyBiocompatible materialLipids030104 developmental biologyMolecular MedicineNanoparticlesCurrent gene therapy
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