Search results for "Technique"

showing 10 items of 5596 documents

Cyclic hantavirus epidemics in humans--predicted by rodent host dynamics.

2009

Wildlife-originated zoonotic diseases are a major contributor to emerging infectious diseases. Hantaviruses cause thousands of human disease cases annually worldwide, and understanding and predicting human hantavirus epidemics still poses unsolved challenges. Here we studied the three-level relationships between the human disease nephropathia epidemica (NE), its etiological agent Puumala hantavirus (PUUV) and the rodent host of the virus, the bank vole (Myodes glareolus). A large and long-term data set (14 years, 2583 human NE cases and 4751 trapped bank voles) indicates that the number of human infections shows both seasonal and multi-annual fluctuations, is influenced by the phase of vole…

0106 biological sciencesOrthohantavirusRodentEpidemiologyHantavirus InfectionsPopulationPopulation DynamicsFluorescent Antibody TechniqueAntibodies Viral010603 evolutionary biology01 natural sciencesMicrobiologyPuumala virusVirusRodent Diseases03 medical and health sciencesVirologybiology.animalZoonosesNephropathia epidemicamedicineAnimalsHumansRegistrieseducationEcosystemFinland030304 developmental biologyHantavirus0303 health scienceseducation.field_of_studybiologyHost (biology)ArvicolinaePublic Health Environmental and Occupational Healthvirus diseasesmedicine.diseasebiology.organism_classificationVirology3. Good healthBank voleInfectious DiseasesHemorrhagic Fever with Renal SyndromeParasitologyVoleSeasonsEpidemics
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Comparison of binding properties and early biological effects of elicitins in tobacco cells

1998

Abstract Elicitins are a family of small proteins secreted by Phytophthora species that have a high degree of homology and elicit defense reactions in tobacco (Nicotiana tabacum). They display acidic or basic characteristics, the acidic elicitins being less efficient in inducing plant necrosis. In this study we compared the binding properties of four elicitins (two basic and two acidic) and early-induced signal transduction events (Ca2+ influx, extracellular medium alkalinization, and active oxygen species production). The affinity for tobacco plasma membrane-binding sites and the number of binding sites were similar for all four elicitins. Furthermore, elicitins compete with one another fo…

0106 biological sciencesPhysiologyNicotiana tabacumPlant Science01 natural sciences[SDV.GEN.GPL]Life Sciences [q-bio]/Genetics/Plants genetics03 medical and health sciencesCell surface receptor[SDV.GEN.GPL] Life Sciences [q-bio]/Genetics/Plants geneticsGeneticsExtracellularBinding siteComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesbiologyBinding proteinElicitinTECHNIQUE DES TRACEURSbiology.organism_classificationElicitorBiochemistryCULTURE DE CELLULESignal transduction010606 plant biology & botanyResearch Article
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Risk of predation makes foragers less choosy about their food.

2017

18 pages; International audience; Animals foraging in the wild have to balance speed of decision making and accuracy of assessment of a food item's quality. If resource quality is important for maximizing fitness, then the duration of decision making may be in conflict with other crucial and time consuming tasks, such as anti-predator behaviours or competition monitoring. Individuals facing the risk of predation and/or competition should adjust the duration of decision making and, as a consequence, their level of choosiness for resources. When exposed to predation, the forager could either maintain its level of choosiness for food items but accept a reduction in the amount of food items con…

0106 biological sciencesPhysiologylcsh:MedicinePredationSocial SciencesKaplan-Meier EstimateChoice Behavior01 natural sciencesPredationCognitionMathematical and Statistical TechniquesBeetlesMedicine and Health Sciences[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisPsychologyForagingDecision-makinglcsh:Sciencemedia_common2. Zero hungerMultidisciplinaryEcologyAnimal BehaviorEcology05 social sciencesEukaryotaPlantsTrophic InteractionsInsectsCommunity EcologyPhysical SciencesSeedsStatistics (Mathematics)Research ArticleRiskOpportunity costArthropodaMovementmedia_common.quotation_subjectDecision MakingForagingBiologyResearch and Analysis Methods010603 evolutionary biologyIntraspecific competitionCompetition (biology)Food PreferencesAnimals0501 psychology and cognitive sciencesQuality (business)050102 behavioral science & comparative psychologyStatistical MethodsBehavior[ SDE.BE ] Environmental Sciences/Biodiversity and Ecologylcsh:REcology and Environmental SciencesCognitive PsychologyFood ConsumptionOrganismsBiology and Life SciencesInterspecific competitionInvertebratesFoodPredatory BehaviorCognitive Sciencelcsh:QWeeds[SDE.BE]Environmental Sciences/Biodiversity and EcologyPhysiological ProcessesZoologyMathematicsNeuroscienceGeneralized Linear ModelDemography[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Monitoring the reproductive activity in captive bred female ball pythons (P. regius) by ultrasound evaluation and noninvasive analysis of faecal repr…

2018

The royal python (Python regius) is commonly bred in captivity. To have a successful breeding season, accurate monitoring of the reproductive activity is necessary. The use of non-invasive monitoring methods in exotics is important in order to minimize stress. For this purpose ultrasound has been anecdotally used to monitor royal python reproductive activity. However, there is limited information regarding the reproductive cycle of this species. The aim of the present study is to monitor the female reproductive cycle of the royal python using ultrasonography and gonadal steroid metabolite measurements in the faeces. The reproductive activity of one hundred twenty-nine adult female P. regius…

0106 biological sciencesRoyal python (Python regius) female reproductive activity captive bred ultrasound evaluation faecal reproductive hormone metabolites progesterone 17β-estradiol noninvasive analysislcsh:MedicineCaptivityPhysiologyBiochemistry01 natural sciencesDiagnostic Radiology0403 veterinary scienceFecesUltrasound ImagingFollicular phaseMedicine and Health SciencesMetabolitesSeasonal breederLipid Hormonesfaecal reproductive hormone metabolitesPythonslcsh:ScienceUltrasonographyMultidisciplinaryEstradiolOrganic CompoundsReproductionRadiology and ImagingEukaryotaSnakes04 agricultural and veterinary sciencesSlugsSquamatesChemistrycaptive bredVertebratesPhysical SciencesRoyal python (Python regius)FemaleSteroidsFolliculogenesisResearch ArticleImaging Techniques040301 veterinary sciencesprogesteroneBiologyResearch and Analysis Methods010603 evolutionary biologyDiagnostic MedicineSex HormonesAnimalsFecesOrganic Chemistrylcsh:ROrganismsChemical Compoundsultrasound evaluation17β-estradiolBiology and Life SciencesReptilesEchogenicityMolluscsbiology.organism_classificationInvertebratesHormonesMetabolismfemale reproductive activityGastropodsnoninvasive analysisAmniotesRoyal pythonlcsh:QHormonePLOS ONE
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Implications of the EFSA Scientific Opinion on Site Directed Nucleases 1 and 2 for Risk Assessment of Genome-Edited Plants in the EU

2021

Genome editing is a set of techniques for introducing targeted changes in genomes. It may be achieved by enzymes collectively called site-directed nucleases (SDN). Site-specificity of SDNs is provided either by the DNA binding domain of the protein molecule itself or by RNA molecule(s) that direct SDN to a specific site in the genome. In contrast to transgenesis resulting in the insertion of exogenous DNA, genome editing only affects specific endogenous sequences. Therefore, multiple jurisdictions around the world have exempted certain types of genome-edited organisms from national biosafety regulations completely, or on a case-by-case basis. In the EU, however, the ruling of the Court of J…

0106 biological sciencesSDN-2SDN-1Mutagenesis (molecular biology technique)Computational biology01 natural sciencesGenomegenome-edited organismlcsh:Agriculture03 medical and health sciencesBiosafetyGenome editingsite-directed nucleasegenetically modified organismJustice (ethics)EFSA opinion030304 developmental biology0303 health sciencesScope (project management)business.industrylcsh:SFood safetyDirectiveBusinessAgronomy and Crop Science010606 plant biology & botanyAgronomy
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Regulation of reactive oxygen species production by a 14-3-3 protein in elicited tobacco cells.

2007

International audience; The regulation of the system responsible for the production of reactive oxygen species (ROS) during plant–microorganism interaction is still largely unknown. The protein NtrbohD has been recently demonstrated as the plasma membrane oxidase responsible for ROS production in elicited tobacco cells. Here, its C-terminus part was used as a bait in a two-hybrid screen in order to identify putative regulators of this system. This led to the isolation of a cDNA coding for a member of the 14-3-3 protein family. The corresponding transcript was induced after infiltration of tobacco leaves with the fungal elicitor cryptogein. Tobacco cells transformed with an antisense constru…

0106 biological sciencesSIGNALLINGDNA ComplementaryProtein familyPhysiologyMolecular Sequence DataContext (language use)Plant ScienceBiology01 natural sciences03 medical and health sciencesTwo-Hybrid System TechniquesTobaccoNADPH OXIDASEAmino Acid Sequence14-3-3 protein030304 developmental biologychemistry.chemical_classification[SDV.EE]Life Sciences [q-bio]/Ecology environment0303 health sciencesReactive oxygen speciesOxidase testCRYPTOGEINNADPH oxidaseSequence Homology Amino AcidElicitorchemistryBiochemistry14-3-3 ProteinsNAD(P)H oxidasebiology.proteinReactive Oxygen Species010606 plant biology & botanyPlant, cellenvironment
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Long-term effects of elevated CO2 on the population dynamics of the seagrass Cymodocea nodosa: Evidence from volcanic seeps

2021

Population reconstruction techniques was used to assess for the first time the population dynamics of a seagrass, Cymodocea nodosa, exposed to long-term elevated CO2 near three volcanic seeps and compared them with reference sites away from the seeps. Under high CO2, the density of shoots and of individuals (apical shoots), and the vertical and horizontal elongation and production rates, were higher than at the reference sites. Nitrogen limitation effects on rhizome elongation and production rates and on biomass were more evident than CO2 as these were highest at the location where the limitation of nitrogen was highest. At the seep where the availability of CO2 was highest and nitrogen low…

0106 biological sciencesSettore BIO/07 - EcologiaPopulation dynamicsCymodocea nodosaPopulation2010501 environmental sciencesAquatic ScienceOceanography01 natural sciencesVolcanic COMediterranean SeaHumansSeawaterBiomasseducationSeagrass0105 earth and related environmental sciencesseepsBiomass (ecology)education.field_of_studyAlismatalesbiology010604 marine biology & hydrobiologyOcean acidificationfood and beveragesOcean acidificationVolcanic CO2 seepsCarbon Dioxidebiology.organism_classificationPollutionRhizomeReconstruction techniquesPetroleum seepSeagrassAgronomyShoot
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Mediterranean forage legumes grown alone or in mixture with annual ryegrass: biomass production, N2 fixation, and indices of intercrop efficiency

2016

Aims: To evaluate the productivity and N2 fixation of a range of Mediterranean forage legume species as well as their ability to be grown in mixture with a forage grass, and to verify whether N transfer occurs from the legume to the non-legume component of the mixtures and, if so, to what extent this process is affected by legume species. Methods: Seven legume species (Hedysarum coronarium L., Medicago scutellata L., Trifolium resupinatum L., Trifolium squarrosum L., Trigonella foenum-graecum L., Vicia sativa L., Vicia villosa Roth) were grown alone or in mixture with annual ryegrass (Lolium multiflorum L.). Biomass and N yields and biological N2 fixation (15N dilution technique) were measu…

0106 biological sciencesSullaVicia sativaFenugreek15N-isotope techniqueSoil ScienceForagePlant Science01 natural sciencesLegumeBiomass (ecology)biologyIntercropping04 agricultural and veterinary sciencesLolium multiflorumbiology.organism_classificationSettore AGR/02 - Agronomia E Coltivazioni ErbaceeTrifolium resupinatumPersian cloverVicia villosaAgronomy040103 agronomy & agricultureHairy vetch0401 agriculture forestry and fisheriesSquarrosum cloverIntercrop010606 plant biology & botanySnail medick
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Reconstruction and analysis of genome-scale metabolic model of a photosynthetic bacterium

2010

Abstract Background Synechocystis sp. PCC6803 is a cyanobacterium considered as a candidate photo-biological production platform - an attractive cell factory capable of using CO2 and light as carbon and energy source, respectively. In order to enable efficient use of metabolic potential of Synechocystis sp. PCC6803, it is of importance to develop tools for uncovering stoichiometric and regulatory principles in the Synechocystis metabolic network. Results We report the most comprehensive metabolic model of Synechocystis sp. PCC6803 available, iSyn669, which includes 882 reactions, associated with 669 genes, and 790 metabolites. The model includes a detailed biomass equation which encompasses…

0106 biological sciencesSystems biologyIn silicoMetabolic networkComputational biologyBiologyModels Biological01 natural sciencesMetabolic engineeringGene Knockout Techniques03 medical and health sciencesStructural BiologyModelling and Simulation010608 biotechnologyBotanyBiomassPhotosynthesislcsh:QH301-705.5Molecular Biology030304 developmental biologyAutotrophic Processes0303 health sciencesGene Expression ProfilingApplied MathematicsSynechocystisSynechocystisGenomicsDarknessbiology.organism_classificationComputer Science ApplicationsFlux balance analysislcsh:Biology (General)Genes BacterialAutotrophic ProcessesModeling and SimulationEnergy sourceGenome BacterialResearch ArticleBMC Systems Biology
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Effect of acyl-CoA oxidase activity on the accumulation of gamma-decalactone by the yeast Yarrowia lipolytica: a factorial approach.

2007

International audience; beta-Oxidation is a cyclic pathway involved in the degradation of lipids. In yeast, it occurs in peroxisomes and the first step is catalyzed by an acyl-CoA oxidase (Aoxp). The yeast Yarrowia lipolytica possesses several genes (POX) coding for Aoxps. This study is based on the factorial analysis of results obtained with the many POX derivative strains that have been constructed previously. The effect of interactions between Aoxps on the acyl-CoA oxidase (Aox) activity was important even at the second order. We then investigated the effect of Aox activity on growth and lactone production. Aox activity was correlated with acidification of the medium by cells and with ce…

0106 biological sciencesYarrowia lipolyticaMESH: Enzyme ActivationMetabolic Clearance RateMESH: Factor Analysis StatisticalYarrowiaBiologymodèleModels Biological01 natural sciencesApplied Microbiology and BiotechnologyLactones03 medical and health sciencesEnzyme activatorSpecies SpecificityMESH: Computer Simulation010608 biotechnologyCombinatorial Chemistry TechniquesAcyl-CoA oxidaseMESH: Species SpecificityComputer Simulation030304 developmental biologychemistry.chemical_classificationMESH: Metabolic Clearance Rate0303 health sciencesOxidase testmétabolisme des acides grasAcyl-CoA oxidase activityMESH: Acyl-CoA OxidaseMESH: Models BiologicalYarrowia[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologyGeneral MedicinePeroxisomebiology.organism_classificationYeastEnzyme ActivationBiochemistrychemistrylactoneMolecular MedicineMESH: Combinatorial Chemistry TechniquesMESH: YarrowiaAcyl-CoA OxidaseFactor Analysis StatisticalLactoneMESH: Lactones
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