Search results for "Tonicity"

showing 8 items of 28 documents

�ber die Wirkung hypotoner Salzl�sungen auf das Rattenzwerchfell

1954

Es wird die Wirkung hypotoner Salzlosungen auf das isolierte Rattenzwerchfell beschrieben. Auf 5/10–6/10 der Isotonie verdunnte Tyrodelosungen fuhren an Muskeln, die bereits langere Zeit im Versuch sind, zu einer dauernden Verstarkung der elektrisch ausgelosten Kontraktionen („hypotoner Effekt“). Mit Saccharose auf Warmbluterisotonie erganzte hypotone Salzlosungen zeigen diesen Effekt nicht. Vermehrung des Kaliums oder Calciums im Austausch gegen Natrium bei erhaltener Hypotonie hemmt den „hypotonen Effekt“, Senkung der Badetemperatur hebt ihn ebenfalls auf.

PharmacologyChemistryPharmacology toxicologyTonicityRat DiaphragmGeneral MedicineMolecular biologyNaunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie
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Gef��- und Tubulusweite der Niere bei osmotischer und Wasserdiurese und nach Theophyllininjektionen

1960

The effects of i.v. administered hypertonic solutions (6-fold isotonic solutions of NaCl, sodium sulfate, glucose and mannitol) theophylline (25 mg/kg) and vasopressin (50 mE/kg) on the blood pressure, cortical kidney vessel blood content and tubulus dilatation were studied in large groups of mice. The blood pressure and blood content effects after i.p. injection of 10% NaCl solution and the blood content during water diuresis were also investigated. The kidney vessel blood content was determined through benzidine stained erythrocytes in kidney slices. An increase in blood content as compared to corresponding controls was consistently noted after i.v. injection of 6-fold isotonic solutions …

PharmacologyVasopressinmedicine.medical_specialtyKidneyChemistrymedicine.medical_treatmentIntraperitoneal injectionGeneral MedicineEndocrinologymedicine.anatomical_structureInternal medicineRenal physiologymedicineTonicityMannitolIsotonic Solutionsmedicine.drugBlood vesselNaunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie
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Nonlinear scalar field equations with general nonlinearity

2018

Consider the nonlinear scalar field equation \begin{equation} \label{a1} -\Delta{u}= f(u)\quad\text{in}~\mathbb{R}^N,\qquad u\in H^1(\mathbb{R}^N), \end{equation} where $N\geq3$ and $f$ satisfies the general Berestycki-Lions conditions. We are interested in the existence of positive ground states, of nonradial solutions and in the multiplicity of radial and nonradial solutions. Very recently Mederski [30] made a major advance in that direction through the development, in an abstract setting, of a new critical point theory for constrained functionals. In this paper we propose an alternative, more elementary approach, which permits to recover Mederski's results on the scalar field equation. T…

Pure mathematicsMathematics::Analysis of PDEsMonotonic function2010 MSC: 35J20 35J6001 natural sciencesMathematics - Analysis of PDEsFOS: Mathematics[MATH.MATH-AP]Mathematics [math]/Analysis of PDEs [math.AP]Mountain pass0101 mathematicsMathematicsgeographygeography.geographical_feature_category35J20 35J60Applied Mathematics010102 general mathematicsMultiplicity (mathematics)Monotonicity trickNonradial solutions010101 applied mathematicsNonlinear systemBerestycki-Lions nonlinearityBounded functionNonlinear scalar field equationsScalar fieldAnalysisAnalysis of PDEs (math.AP)
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SNAT2 silencing prevents the osmotic induction of transport system A and hinders cell recovery from hypertonic stress.

2005

AbstractUnder hypertonic conditions the induction of SLC38A2/SNAT2 leads to the stimulation of transport system A and to the increase in the cell content of amino acids. In hypertonically stressed human fibroblasts transfection with two siRNAs for SNAT2 suppressed the increase in SNAT2 mRNA and the stimulation of system A transport activity. Under the same condition, the expansion of the intracellular amino acid pool was significantly lowered and cell volume recovery markedly delayed. It is concluded that the up-regulation of SNAT2 is essential for the rapid restoration of cell volume after hypertonic stress.

Small interfering RNAmedicine.medical_specialtyAmino Acid Transport System AGlutamineCellBiophysicsStimulationBiologyTransfectionBiochemistryStructural BiologyOsmotic PressureCell volumeInternal medicineGeneticsmedicineHumansRNA MessengerAmino AcidsRNA Small InterferingMolecular BiologyCell Sizechemistry.chemical_classificationSaline Solution HypertonicCell BiologyFibroblastsAmino acidCell biologyUp-RegulationGlutaminemedicine.anatomical_structureEndocrinologychemistryHypertonic StresssiRNATonicityRNA InterferenceIntracellularFEBS letters
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Monotonicity Formulas for Harmonic Functions in RCD(0,N) Spaces

2023

We generalize to the RCD(0,N) setting a family of monotonicity formulas by Colding and Minicozzi for positive harmonic functions in Riemannian manifolds with nonnegative Ricci curvature. Rigidity and almost rigidity statements are also proven, the second appearing to be new even in the smooth setting. Motivated by the recent work in Agostiniani et al. (Invent. Math. 222(3):1033–1101, 2020), we also introduce the notion of electrostatic potential in RCD spaces, which also satisfies our monotonicity formulas. Our arguments are mainly based on new estimates for harmonic functions in RCD(K,N) spaces and on a new functional version of the ‘(almost) outer volume cone implies (almost) outer metric…

differentiaaligeometriaRCD spacesmonotonicity formulaalmost rigidityharmonic functions
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Multidimensional Health Modelling: Association between Socioeconomic Factors and Health in Latvia

2012

This paper proposes new approach for modelling self-assessed health. We find that the concept of health is too complicated to measure effects of health determinants using a one-dimensional econometric model. We apply two-dimensional stereotype logistic model that allows capturing nonmonotonicity in effects of factors and revealing significant effects that remain unrevealed if single dimension models, such as ordered logit or ordered probit, are used. Modelling self-assessed health using multi-dimensional stereotype logit provides higher model goodness of fit and quality measures in comparison to ordered probit model. Multi-dimensional stereotype logit is applied to estimate association betw…

jel:I18jel:C52Self-assessed health Socioeconomic determinants Nonmonotonicity Stereotype logitjel:I10Economic Research Guardian
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Botulinum toxin associated with fissurectomy and anoplasty for hypertonic chronic anal fissure: A case-control study.

2021

BACKGROUND Lateral internal sphincterotomy is still the approach of choice for the treatment of chronic anal fissure (CAF) with internal anal sphincter (IAS) hypertonia, but it is burdened by high-risk postoperative faecal incontinence (FI). Sphincter saving procedures have recently been reconsidered as treatments to overcome this risk. The most employed procedure is fissurectomy with anoplasty, eventually associated with pharmacological sphincterotomy. AIM To evaluate whether fissurectomy and anoplasty with botulinum toxin injection improves the results of fissurectomy and anoplasty alone. METHODS We conducted a case-control study involving 30 male patients affected by CAF with hypertonic …

medicine.medical_specialtybusiness.industryChronic anal fissureCase-control studyGeneral MedicineCase Control StudyAnoplastyBotulinum toxinSurgeryFissurectomyBotulinum toxinAnal fissure; Anoplasty; Botulinum toxin; Fissurectomy; ProctologymedicineTonicityProctologyAnal fissurebusinessmedicine.drugWorld journal of clinical cases
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Multidimensional health modeling: Association between socioeconomic and psychosocial factors and health in Latvia

2009

This research aims at estimating association between socioeconomic and psychosocial factors on the one hand and health in Latvia on the other hand. While information on association between socioeconomic determinants of population health in Latvia is scarce, effect of psychosocial resources on individual health in this country hasn’t been estimated before. We find empirical support for the association between different psychosocial factors and physical health in Latvia. This paper proposes new approach for modelling self-assessed health. We find that the concept of health is too complicated to measure effects of health determinants using a one-dimensional econometric model. We apply two-dime…

medicine.medical_specialtyjel:C52Public healthLogitOrdered probitPopulation healthLogistic regressionjel:I10Econometric modeljel:I18Political sciencemedicineEconometricsself-assessed health; socioeconomic determinants; psychosocial factors; nonmonotonicity; stereotype logitOrdered logitPsychosocial
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