Search results for "Tonsil"
showing 10 items of 59 documents
Trattamento medico dell'ascesso peritonsillare
2012
Aukslēju mandeļu kriptolīzes vēlīnu rezultātu novērtēšana
2019
Darba aktualitāte: Aukslēju mandeļukriptolīze ir salīdzinoši jauna ārstēšanas pieeja otorinolaringoloģijas jomā. Pirmie pētījumu ziņojumi meklējami vien 1994.gadā. Kopš tā laika arvien nav atrasti objektīvi, reāli diagnosticējami pacientu atlases kritēriji, kuriem šī ārstēšanas metode varētu sniegt labākos rezultātus ilgtermiņā. Šobrīd biežākais šīs procedūras veikšanas iemesls ir hronisks kazeozs tonsilīts (CCT), ko pavada tādi simptomi kā bāli dzeltenīgu, biezpienam līdzīgu graudiņu jeb t.s. detrīra korķu veidošanās, halitoze (slikta elpa, “foetor ex ore”), nepatīkama piegaršā mutē, pastāvīga diskomforta vai niezēšanas sajūtas rīklē, kā arī svešķermeņa sajūta rīklē. Lai arī šis patoloģisk…
BiZact tonsilektomijas un konvencionālās tonsilektomijas metožu salīdzinājums
2022
Paskaidrojošā informācija: Tonsilektomija ir viena no visbiežāk veiktajām ķirurģiskajām operācijām cilvēces vēsturē. Tonsilektomija tehnoloģijas un procedūras gadu gaitā ir attīstījušās, lai uzlabotu pacientu aprūpi saistībā ar intraoperācijas un pēcoperācijas riskiem. Mērķis: Šī pētījuma mērķis ir salīdzināt BiZact tonsilektomijas metodi ar tradicionālo «aukstās pieejas» tērauda tonsilektomijas metodi attiecībā uz ķirurģiskajiem rezultātiem. Nolūks: Klasiskā «aukstās pieejas» tērauda tonsilektomijas metode ir viena no visbiežāk izmantotajām metodēm, un tā ir balstīta uz tonsilektomijas instrumentiem, jo ar tiem ir viegli strādāt, tiem nav nepieciešama elektrība (un līdz ar to tie ir vienkā…
Bipolar Quantum Molecular Resonance versus Blunt Dissection tonsillectomy
2015
Bipolar Quantum Molecular Resonance versus Blunt Dissection tonsillectomy. Objectives: This study compared a quantum molecular resonance tonsillectomy (QMRT) to a standard blunt dissection tonsillectomy (BDT) for effectiveness and safety. Methodology: From January 2011 to September 2012, we recruited 80 children (ages 3 to 16 y) with paediatric obstructive sleep apnoea syndrome and/or recurrent tonsillitis. Patients were randomly assigned to receive QMRT (N = 40) or BDT (N = 40). The operating time and blood loss during surgery were evaluated. During the first postoperative week, the patients' parents completed a questionnaire to evaluate bleeding, ear and neck pain, nausea, vomiting, inter…
Incidence and anatomy of gaze-evoked nystagmus in patients with cerebellar lesions.
2011
Background: Disorders of gaze-holding—organized by a neural network located in the brainstem or the cerebellum—may lead to nystagmus. Based on previous animal studies it was concluded that one key player of the cerebellar part of this gaze-holding neural network is the flocculus. Up to now, in humans there are no systematic studies in patients with cerebellar lesions examining one of the most common forms of nystagmus: gaze-evoked nystagmus (GEN). The aim of our present study was to clarify which cerebellar structures are involved in the generation of GEN. Methods: Twenty-one patients with acute unilateral cerebellar stroke were analyzed by means of modern MRI-based voxel-wise lesion-behavi…
Reduced T-cell receptor CD3ζ-chain protein and sustained CD3ε expression at the site of mycobacterial infection
2001
Control of mycobacterial infection by the cellular immune system relies both on antigen-presenting cells and on T lymphocytes. The quality of an effective cellular immune response is dependent on functional signal transduction residing in the cytoplasmic tails of the T-cell receptor CD3 components. In order to investigate potential effects of mycobacteria on T-cell receptor signalling, we examined the protein expression of T-cell signal transduction molecules (CD3zeta, ZAP-70, p59fyn, p56lck). In Western blots of peripheral blood mononuclear cells of Mycobacterium tuberculosis infected patients, only the CD3zeta-chain showed a marked reduction in protein expression. To investigate the situa…
Autocrine transforming growth factor- from chronic lymphocytic leukemia-β cells interferes with proliferative T cell signals
1999
Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of noncycling B cells in lymphatic and extralymphatic tissues. In the present study we investigated the possible contribution of TGF-beta, as secreted by CLL-B cells, on this low proliferative state. CLL-B cells were shown to express TGF-beta RNA and to release bioactive TGF-beta into culture supernatants. Antibody neutralization of endogenously secreted TGF-beta increased the proliferation of CLL-B cells as cultured in the presence of IL-2 or IL-4 or in direct contact with activated CD4+ T cells. In these culture systems, addition of exogenous TGF-beta downregulated basal and cytokineinduced proliferation of CLL-B cell…
Different patterns of cytokeratin expression in the normal epithelia of the upper respiratory tract
1985
The distribution and type of cytokeratins present in the normal human epithelia of the nasopharynx, oropharynx, tongue, palatine tonsil, epiglottis, vocal cord, and laryngeal ventricle were studied using immunohistochemical techniques and by gel electrophoresis of cytoskeletal proteins microdissected from frozen tissues. Noncornifying stratified epithelia covering the oropharynx, tongue, surface of the palatine tonsil, pharyngeal surface of the epiglottis, and vocal cord were all found to contain cytokeratins nos. 4, 5, 6, 13, 14, and 15, together with minor amounts of cytokeratin no. 19, i.e., a pattern similar to that previously reported for esophageal epithelium. The immunohistochemical …
Abstract PO-35: Prognostic significance of MYC, BCL2, and BCL6 colocalization at single-cell resolution in DLBCL
2020
Abstract MYC, BCL2, and BCL6 are commonly used markers for immunohistochemistry of Diffuse large B-cell lymphomas (DLBCL). Coexpression of MYC and BCL2 in particular constitutes a subgroup of “double expressor lymphomas” (DEL) with a distinct poor clinical outcome. However, it is not known if MYC and BCL2/BCL6 coexpression occurs in the same cell or in different cells within the tumor, as traditional immunohistochemistry (IHC) is limited by the number of markers that can be simultaneously assessed within formalin-fixed, paraffin-embedded (FFPE) samples. We set out to discover the clinical significance of MYC, BCL2, and BCL6 colocalization at single-cell resolution using multiplexed quantita…
Effects of adenotonsillectomy on neurocognitive and behavioural function in pediatric obstructive sleep apnea syndrome
2018
Effects of adenotonsillectomy on neurocognitive and behavioural function in pediatric obstructive sleep apnea syndrome. Objectives: Aim of this study is to verify the presence of neurocognitive, neurobehavioral or sleep disturbances in children affected by adenotonsillar hypertrophy (ATH) and Obstructive Sleep Apnea Syndrome (OSAS) and verify their improvement after Adeno-Tonsillectomy (AT). Methods: Eighty children suffering from adenotonsillar hypertrophy and OSAS were recruited for AT in the ENT Department of the University of Palermo. All the children underwent clinical evaluation, including rhinofibroscopy for grading the obstruction due to the adenotonsillar hypertrophy (before and 6 …