Search results for "Trace"
showing 10 items of 3218 documents
Formulative and stability studies of a Citrus extract to produce novel “healthy food"
2015
Anti-inflammatory properties of an aldehydes-enriched fraction of grapefruit essential oil
2023
Chronic inflammation is linked to the development of numerous diseases and is accompanied by increased cytokine secretion. Macrophages provide a first line of defense against pathogens that under inflammatory stimuli release pro-inflammatory cytokines. The essential oil (EO) fractions obtained from Citrus spp. rich in different compounds have gained the attention of both researchers and users during the last decades. In particular, grapefruit (Citrus paradisi) peel is rich in phenolics and flavonoids with several health benefits, including anti-inflammatory actions. Additionally, its EO consists of a large number of compounds such as monoterpenes, sesquiterpenes, alcohols, aldehydes, esters…
Cultivated mushrooms: importance of a multipurpose crop, with special focus on Italian fungiculture
2020
Fungi, organisms of high nutritional value with significant bioactive compound content, are considered to be nutraceuticals, mycotherapeutics, cosmeceuticals and useful for the production of functional foods. Their cultivation allows the sustainable management of agro-industrial wastes and generates good income with low inputs, constituting a good opportunity for the development of economically depressed rural areas. There are also many possible uses for the spent substrate in various sectors. provide an overview of the nutritional value of mushrooms and the cultivation of edible and medicinal mushrooms cultivation and uses in Italy.
Drug Induced Liver Injury (DILI) due to variability in monacolin K content in Red Yeast Rice (RYR): An expert opinion
2020
Abstract Introduction Red yeast rice (RYR) is an effective cholesterol-lowering nutraceutical reversibly inhibiting 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase. As liver damage is a possible (albeit rare) side effect of HMG-CoA inhibitors, it make sense to focus on the tolerability of the liver to RYR extracts. The aim of this paper is to offer an expert opinion on the risk of liver damage by the use of RYR extract. Methods A review of the available literature has been carried out and critically reviewed by the authors. Results According to a large meta-analysis of 53 randomized clinical trials comprising 112 treatment arms, which included 8535 subjects with 4437 in the RYR arm and …
Adipose Stromal/Stem Cell-Derived Extracellular Vesicles: Potential Next-Generation Anti-Obesity Agents
2022
Over the last decade, several compounds have been identified for the treatment of obesity. However, due to the complexity of the disease, many pharmacological interventions have raised concerns about their efficacy and safety. Therefore, it is important to discover new factors involved in the induction/progression of obesity. Adipose stromal/stem cells (ASCs), which are mostly isolated from subcutaneous adipose tissue, are the primary cells contributing to the expansion of fat mass. Like other cells, ASCs release nanoparticles known as extracellular vesicles (EVs), which are being actively studied for their potential applications in a variety of diseases. Here, we focused on the importance …
Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity
2021
Centrioles comprise the heart of centrosomes, microtubule-organizing centers. To study the function of centrioles in lung and gut development, we genetically disrupted centrioles throughout the mouse endoderm. Surprisingly, removing centrioles from the endoderm did not disrupt intestinal growth or development but blocked lung branching. In the lung, acentriolar SOX2-expressing airway epithelial cells apoptosed. Loss of centrioles activated p53, and removing p53 restored survival of SOX2-expressing cells, lung branching, and mouse viability. To investigate how endodermal p53 activation specifically killed acentriolar SOX2-expressing cells, we assessed ERK, a prosurvival cue. ERK was active t…
New results and review of major and trace element output from worldwide passive degassing volcanoes
2013
Analytical Method for Quantification of Several Phthalate Acid Esters by Gas Chromatography-Mass Spectrometry in Coffee Brew Samples
2022
Several phthalate acid esters (PAEs), often called phthalate esters or phthalates, are substances classified as harmful due to their carcinogenic and mutagenic properties, and moreover, as dangerous for humans because they interfere with the endocrine system. In general, phthalic esters are used as plasticizers for different polymers and more other consumer products. In the present study, we describe a simple method to quantify PAEs in coffee brew using a liquid-liquid extraction without purification processes through analysing the obtained organic phase by GCMS in the single ion monitoring mode. The totals of single PAEs, in coffee brew samples analysed by us, are in the range of 159-5305 …
Práctica 12. Montaje con biseladora automática 3_A con tracer, plantilla o lentes demo, de unas lentes esfero-cilíndricas orgánicas y/o minerales, so…
2022
Montaje con biseladora automática 3_A con tracer, plantilla o lentes demo, de unas lentes esfero-cilíndricas orgánicas y/o minerales, sobre monturas de acetato y/o metal.
Práctica 13. Montaje con biseladora automática 3_B con tracer, plantilla o lentes demo, de unas lentes esfero-cilíndricas orgánicas y/o minerales, so…
2022
Montaje con biseladora automática 3_B con tracer, plantilla o lentes demo, de unas lentes esfero-cilíndricas orgánicas y/o minerales, sobre monturas de acetato y/o metal.