Search results for "Trail"
showing 10 items of 126 documents
TRAIL signalling regulation by ezrin
2011
Background and Aim: TRAIL has sparked a growing interest in oncology due to its ability to selectively trigger cancer cell death while sparing normal cells. The Fas/actin association through ezrin, a member of the ERM protein family, has been reported to regulate early steps of Fas-mediated apoptosis. In this project, we addressed the role of ezrin regarding TRAIL-induced cell death in B lymphoma cell lines, or adherent cancer cell lines (HeLa WT, HCT116, SW480). Methods: Molecular and biochemical approaches were employed to study the relevance of ezrin and its phosphorylation status in TRAIL signaling. Results: We found that ezrin displays a negative function towards TRAIL- and Fas-mediate…
Sistēmas audita pierakstu attēlojums lietotājam ērtā veidā.
2017
Kvalifikācijas darbā ir aprakstīta sistēmas apakšsadaļas izstrāde, kas lietotājam ļauj ātri un ērti pārskatīt visas sistēmā veiktās darbības un izmaiņas. Galvenais darba mērķis bija apvienot sistēmas audita pierakstus ar to ietvaros veiktajām izmaiņām sistēmā. Izstrādātā apakšsadaļa ir daļa no uzņēmuma Lojalitātes vadības pakalpojumu sistēmas, un to paredzēts lietot sistēmas administratoriem uzņēmumā, kas ne vienmēr ir izglītoti datorzinātņu jomā, tāpēc svarīgākais uzdevums, bija izveidot audita pierakstu pārskatu ērtu un viegli saprotamu. Tas, galvenokārt, tika panākts ar to, ka audita pieraksti tika pārveidoti teikumu veidā, lai to nozīmi saprastu ikviens. Šis dokuments satur izstrādātās …
(Z)-dodec-3-en-1-ol, a novel termite trail pheromone identified after solid phase microextraction from Macrotermes annandalei
2001
0022-1910 (Print) Journal Article; (Z)-dodec-3-en-1-ol was isolated and identified by GC-MS as the major component of the trail-following pheromone from whole body and sternal gland extracts of workers of the fungus-growing termite, Macrotermes annandalei (Silvestri) (Termitidae, Macrotermitinae). For the first time, this trail pheromone was also identified by using solid phase microextraction from the surface of the secretory sternal gland of workers. Bioassays showed that synthetic dodecenol induced both orientation and recruitment behavioral effects. The activity threshold of (Z)-dodec-3-en-1-ol in eliciting trail-following is similar to that of (3Z,6Z,8E)-dodeca-3,6,8-trien-1-ol in the …
Impact Assessment of Skidding Extraction: Effects on Physical and Chemical Properties of Forest Soils and on Maple Seedling Growing along the Skid Tr…
2019
Several studies investigated soil disturbances caused on skid trails by forest logging. However, there is still a lack of knowledge about the severity and the distance of disturbances along both sides from the trails. The aims of this study were: i) to investigate the changes in physical and chemical properties of soil along the sides of skidding trails
Combining conventional chemotherapy and γδ T cell-based immunotherapy to target cancer-initiating cells.
2013
According to common beliefs, conventional anticancer chemotherapy is deleterious for the immune system. We have recently provided in vitro evidence indicating that conventional chemotherapy may potentiate, rather than impair, the long-term efficacy of γδ T cell-based anticancer immunotherapy.
The cannabinoid WIN induces DR5 receptor expression in hepatoma cells sensitizing them to TRAIL signal
2009
Participant characteristics associated with the effects of a physical and cognitive training program on executive functions
2022
Background: Physical and cognitive interventions have been shown to induce positive effects on older adults’ executive functioning. However, since participants with different background characteristics may respond differently to such interventions, we investigated whether training effects on executive functions were associated with sex, training compliance, and age. We also investigated if change in global cognition was associated with physical and cognitive training intervention-induced changes in executive functions. Methods: Exploratory data from a randomized controlled trial were analyzed. Participants were 70–85-year-old men and women who received a 12-month physical (PT) or physical a…
The Association between Cognitive Impairment and Diabetic Foot Care: Role of Neuropathy and Glycated Hemoglobin
2020
Diabetes mellitus is associated with impairment in cognitive functions which can complicate adherence to self-care behaviors. We evaluated the incidence of cognitive impairment in patients with diabetes mellitus to determine the strength of the association between diabetic foot (a complication that occurs in about 10% of diabetic patients), adherence to the clinician&rsquo
Na szlaku "królowej śląskich zup"
2018
Przedmiotem niniejszego opracowania jest wodzionka – jedna z charakterystycznych zup śląskich, która w ostatnich kilku latach stała się kulinarną atrakcją Górnego Śląska. Zupa ta, mająca wiele lokalnych odmian, doczekała się swojego przeboju, felietonów w prasie oraz w Internecie, programów kulinarnych, festynów itd., co niewątpliwie przyczynia się do promocji tak samej potrawy, jak i odkrywania dziedzictwa kulinarnego tego regionu, z którym jest utożsamiana. Materiał, który stał się podstawą analizy, pochodzi z dwóch źródeł: zastanych (literatura przedmiotu, w tym również archiwalna, materiały internetowe) i wywołanych (wywiady przeprowadzone w latach 2007-2017 z mieszkańcami dwóch wojewód…