Search results for "Trajectorie"
showing 10 items of 75 documents
ELSA 2014 Cohort: Risk Factors Associated With Heavy Episodic Drinking Trajectories in Argentinean College Students
2020
Heavy episodic drinking (HED) is highly prevalent in college students. In Argentina, there is a notable lack of longitudinal studies examining drinking trajectories. The present study identified HED trajectories in Argentinean college students during the first 3 years of college (seven waves) and examined the association between risk factors for alcohol use and HED trajectories. The sample was composed of 1,240 college students [63.1% women, aged 18–25 years (M = 19.1 ± 1.7)] who completed at least three waves (the first data collection and ≥2 follow-ups). For 3 years, participants completed seven surveys that measured HED frequency, age of drinking onset, drunkenness occurrence, trait impu…
Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM
2019
Single-cell transcriptomic assays have enabled the de novo reconstruction of lineage differentiation trajectories, along with the characterization of cellular heterogeneity and state transitions. Several methods have been developed for reconstructing developmental trajectories from single-cell transcriptomic data, but efforts on analyzing single-cell epigenomic data and on trajectory visualization remain limited. Here we present STREAM, an interactive pipeline capable of disentangling and visualizing complex branching trajectories from both single-cell transcriptomic and epigenomic data. We have tested STREAM on several synthetic and real datasets generated with different single-cell techno…
Genetic association study of childhood aggression across raters, instruments, and age
2021
AbstractChildhood aggressive behavior (AGG) has a substantial heritability of around 50%. Here we present a genome-wide association meta-analysis (GWAMA) of childhood AGG, in which all phenotype measures across childhood ages from multiple assessors were included. We analyzed phenotype assessments for a total of 328 935 observations from 87 485 children aged between 1.5 and 18 years, while accounting for sample overlap. We also meta-analyzed within subsets of the data, i.e., within rater, instrument and age. SNP-heritability for the overall meta-analysis (AGGoverall) was 3.31% (SE = 0.0038). We found no genome-wide significant SNPs for AGGoverall. The gene-based analysis returned three sign…
Quantum collision models: Open system dynamics from repeated interactions
2022
We present an extensive introduction to quantum collision models (CMs), also known as repeated interactions schemes: a class of microscopic system-bath models for investigating open quantum systems dynamics whose use is currently spreading in a number of research areas. Through dedicated sections and a pedagogical approach, we discuss the CMs definition and general properties, their use for the derivation of master equations, their connection with quantum trajectories, their application in non-equilibrium quantum thermodynamics, their non-Markovian generalizations, their emergence from conventional system-bath microscopic models and link to the input-output formalism. The state of the art o…
Learning at work : Researching personal development and competence building in work integration companies
2017
The context of our research is Work Integration Enterprises. These hire people who are emerging from processes of social exclusion for a period of between 6 months and three years. In these companies, people work while learning a trade and learning to work, in order to facilitate their entry into the ordinary labour market.Of the different academic approaches to processes of learning at work and training, we have chosen Michael Eraut's notion of learning trajectories to apply to our research. We have chosen it for its potential: it provides a longitudinal approach to learning, it takes into account technical, social and personal dimensions of learning, and it also develops a particular focu…
(Un)conditioned open dynamics in quantum optics
2021
The study of the dynamics of open quantum systems sheds light on dissipative processes in quantum mechanics. Any system under continuous measurement is open and the act of measuring induces abrupt changes of the system’s state (collapses). The evolution conditioned to measurement records generates the so-called quantum trajectories. A continuous (unconditioned) evolution of the system is recovered by averaging over a large number of trajectories. Historically this kind of evolution has been the main focus of theoretical investigations. In this dissertation we consider both conditional and unconditional dynamics of quantum optical systems. Unconditioned dynamics is studied through the collis…
Ecological Invitation to Engage with Public Displays
2018
Interactive public displays pose several research issues, which include display blindness and interaction blindness. In this paper, we shortly introduce our idea of a sound-based system to overcome the display blindness, and some experiments that we are carrying out in order to test its effectiveness.
Exploiting Semantic Trajectories Using HMMs and BIM for Worker Safety in Dynamic Environments
2020
International audience; Understanding dynamic behaviors of moving objects using positioning technologies for construction safety monitoring is still an open research issue. One task; that is a small subset in the widespread field of objects dynamics is the enrichment of the location data of users with the semantic information for studying their mobility patterns in the context of the environment. However, incorporating the semantics related to the environment gets complex in case of the dynamic construction sites where the site spaces are kept evolving with time. For instance, new walls and infrastructure supports are added often on sites, while others are detached. Similar situations open …
Do dynamic effects play a significant role in enzymatic catalysis? A theoretical analysis of formate dehydrogenase.
2010
A theoretical study of the protein dynamic effects on the hydride transfer between the formate anion and nicotinamide adenine dinucleotide (NAD + ), catalyzed by formate dehydrogenase (FDH), is presented in this paper. The analysis of free downhill molecular dynamic trajectories, performed in the enzyme and compared with the reaction in aqueous solution, has allowed the study of the dynamic coupling between the reacting fragments and the protein or the solvent water molecules, as well as an estimation of the dynamic effect contribution to the catalytic effect from calculation of the transmission coefficient in the enzyme and in solution. The obtained transmission coefficients for the enzyme…
Climatology of the aerosol extinction-to-backscatter ratio from sun-photometric measurements
2010
The elastic lidar equation contains two unknown atmospheric parameters, namely, the particulate optical extinction and backscatter coefficients, which are related through the lidar ratio (i.e., the particulate-extinction-to-backscatter ratio). So far, independent inversion of the lidar signal has been carried out by means of Raman lidars (usually limited to nighttime measurements), high-spectral-resolution lidars, or scanning elastic lidars under the assumption of a homogeneously vertically stratified atmosphere. In this paper, we present a procedure to obtain the lidar ratio at 532 nm by a combined Sunphotometer– aerosol-model inversion, where the viability of the solution is largely reinf…