Search results for "Transferability"

Transferable and Negotiated Knowledge

2002

• Summary: This article explores the knowledge of community-based social workers in the context of an action research project aimed at exploring the practitioners’ own descriptions of their knowledge and expertise on the theme of spatial marginalization. • Findings: The knowledge of social workers seemed to be based on service users’ experiences and case examples, on value and moral constructions, and it was created from experience, by doing and in action. It was local and contextual, in some sense silent but shared through a discussion process. It was not based on empirically based scientific research understood in the traditional sense; rather, social workers resorted to practical knowle…

2020

Domain-specific understanding of digitally represented graphs is necessary for successful learning within and across domains in higher education. Two recent studies conducted a cross-sectional analysis of graph understanding in different contexts (physics and finance), task concepts, and question types among students of physics, psychology, and economics. However, neither changes in graph processing nor changes in test scores over the course of one semester have been sufficiently researched so far. This eye-tracking replication study with a pretest-posttest design examines and contrasts changes in physics and economics students' understanding of linear physics and finance graphs. It analyze…

Improving transferability strategies for debris flow susceptibility assessment: Application to the Saponara and Itala catchments (Messina, Italy)

2017

Abstract Debris flows can be described as rapid gravity-induced mass movements controlled by topography that are usually triggered as a consequence of storm rainfalls. One of the problems when dealing with debris flow recognition is that the eroded surface is usually very shallow and it can be masked by vegetation or fast weathering as early as one-two years after a landslide has occurred. For this reason, even areas that are highly susceptible to debris flow might suffer of a lack of reliable landslide inventories. However, these inventories are necessary for susceptibility assessment. Model transferability, which is based on calibrating a susceptibility model in a training area in order t…

Implantable Sensors Based on Gold Nanoparticles for Continuous Long-Term Concentration Monitoring in the Body.

2021

Implantable sensors continuously transmit information on vital values or biomarker concentrations in bodily fluids, enabling physicians to survey disease progression and monitor therapeutic success. However, currently available technologies still face difficulties with long-term operation and transferability to different analytes. We show the potential of a generalizable platform based on gold nanoparticles embedded in a hydrogel for long-term implanted biosensing. Using optical imaging and an intelligent sensor/reference-design, we assess the tissue concentration of kanamycin in anesthetized rats by interrogating our implanted sensor noninvasively through the skin. Combining a tissue-integ…

Individual patient risk stratification of high-risk neuroblastomas using a two-gene score suited for clinical use

2015

Several gene expression-based prognostic signatures have been described in neuroblastoma, but none have successfully been applied in the clinic. Here we have developed a clinically applicable prognostic gene signature, both with regards to number of genes and analysis platform. Importantly, it does not require comparison between patients and is applicable amongst high-risk patients. The signature is based on a two-gene score (R-score) with prognostic power in high-stage tumours (stage 4 and/or MYCN-amplified diagnosed after 18 months of age). QPCR-based and array-based analyses of matched cDNAs confirmed cross platform (array-qPCR) transferability. We also defined a fixed cut-off value iden…

Determination of fluoxetine enantiomers in pharmaceutical formulations by electrokinetic chromatography-counter current technique

2012

In this work, an electrokinetic chromatography–counter current procedure for the separation of fluoxetine enantiomers using highly sulfated β-cyclodextrin was optimized and applied to the determination of the enantiomers in three pharmaceutical formulations according to the matrix features. Quality criteria were applied to facilitate its transferability to testing laboratories. Fluoxetine was used therapeutically as the racemate, although a stereospecificity associated with its interactions with the neuronal serotonin-uptake carrier was demonstrated. In this context, the development of enantioselective methods for the chiral analysis of pharmaceuticals allowing stereoisomer ratio estimation…

Relationships between Domain-Specific Knowledge, Generic Attributes, and Instructional Skills

2020

We introduce a theoretical framework on teachers’ instructional skills to describe how they can be modeled across different domains. This framework conceptualizes teachers’ instructional skills as action-related skills (during instruction) and reflective skills (before and after instruction), which are considered crucial for coping with the practical demands of everyday teaching in a specific subject. The theoretical framework assumes that both skill facets are influenced by the teacher’s professional knowledge, generic attributes such as general cognitive abilities or ambiguity tolerance as well as affective and motivational factors. To investigate the relationships between teachers’ instr…

Transferability of ASTM/NIST alanine–polyethylene recipe at ISS

2000

Abstract Alanine–polyethylene solid state dosimeters were prepared at Istituto Superiore di Sanita (ISS) following the recipe proposed by National Institute of Standards and Technology (NIST) with the goal of testing its transferability. Dosimeters were prepared using 95% alanine and 5% polyethylene, by weight. They are rugged and of increased sensitivity, repeatability and reproducibility as respect to the ISS alanine-paraffin pellets. Reproducibility of about 1% was obtained at 10 Gy and at 3 Gy if one single pellet or a stack of five dosimeters were used, respectively.

The Chorioallantoic Membrane Assay in Nanotoxicological Research—An Alternative for In Vivo Experimentation

2020

Nanomaterials unveil many applicational possibilities for technical and medical purposes, which range from imaging techniques to the use as drug carriers. Prior to any human application, analysis of undesired effects and characterization of their toxicological profile is mandatory. To address this topic, animal models, and rodent models in particular, are most frequently used. However, as the reproducibility and transferability to the human organism of animal experimental data is increasingly questioned and the awareness of animal welfare in society increases at the same time, methodological alternatives are urgently required. The chorioallantoic membrane (CAM) assay is an increasingly popu…

El model PROT i la responsabilitat social universitaria: prosocialitat i transferència del coneixement a la pràctica

2019

espanolEn 30 anos de historia, el grupo LIPA (Laboratorio de Investigacion Prosocial Aplicada) de la Universidad Autonoma de Barcelona (UAB) ha promovido y generado un modelo internacionalprofesional, de investigacion y formacion para la optimizacion prosocial de los territorios y organizaciones. La Prosocialidad transferida a la practica social en lipa ha generado intervenciones innovadoras que desde una apuesta por la transferencia del conocimiento, ha beneficiado de modo efectivo a personas y organizaciones, potenciando su creatividad, identidad y autonomia. Se sistematizan los resultados de intervencion profesional de proyectos sociales de lipa, para determinar cuales son indicadores de…