Search results for "Tremor"
showing 10 items of 104 documents
Preoperative imaging findings in patients undergoing transcranial magnetic resonance imaging-guided focused ultrasound thalamotomy
2021
AbstractThe prevalence and impact of imaging findings detected during screening procedures in patients undergoing transcranial MR-guided Focused Ultrasound (tcMRgFUS) thalamotomy for functional neurological disorders has not been assessed yet. This study included 90 patients who fully completed clinical and neuroradiological screenings for tcMRgFUS in a single-center. The presence and location of preoperative imaging findings that could impact the treatment were recorded and classified in three different groups according to their relevance for the eligibility and treatment planning. Furthermore, tcMRgFUS treatments were reviewed to evaluate the number of transducer elements turned off after…
Integration of stratigraphic data with HVSR measures for studies of seismic microzonation: the case of Oliveri (ME)
2013
The seismic microzoning is a technique of analysis of a territory which aims to recognize, at a small scale, the local geological and geomorphologic conditions that may significantly affect the characteristics of the seismic motion, generating stress on structures that could produce permanent and critical effects. In other words, this technique has the objective to predict and evaluate possible site effects as a result of an earthquake. The first phase of the seismic microzoning is the detailed partition of the territory in homogeneous areas with respect to the expected behavior of soils during an earthquake. The seismic micro-zoning is a tool for prevention and reduction of seismic risk pa…
Manipulation of HSP70-SOD1 Expression Modulates SH-SY5Y Differentiation and Susceptibility to Oxidative Stress-Dependent Cell Damage: Involvement in …
2023
The differentiation of neural progenitors is a complex process that integrates different signals to drive transcriptional changes, which mediate metabolic, electrophysiological, and morphological cellular specializations. Understanding these adjustments is essential within the framework of stem cell and cancer research and therapy. Human neuroblastoma SH-SY5Y cells, widely used in neurobiology research, can be differentiated into neuronal-like cells through serum deprivation and retinoic acid (RA) supplementation. In our study, we observed that the differentiation process triggers the expression of Heat Shock Protein 70 (HSP70). Notably, inhibition of HSP70 expression by KNK437 causes a dra…
Cluster analysis to support microzonation studies
2015
In recent times the use of microtremor techniques for subsoil investigation increased significantly. The use of HVSR (Horizontal to Vertical Spectral Ratio)technique for seismic microzoning studies allows in many case to obtain detailed reconstruction of the roof of the seismic bedrock and to identify areas with similar seismic behaviour. Two different algorithms of clusteringhave been tested on a HVSR datasets acquired for studies of seismic microzoning in various Sicilian urban centers. HVSR data were previously properly processed to extract frequency and amplitude of peaks by a code based on clustering of HVSR curves determined in sliding time windows.To select an optimal set of time win…
Assessment of the Reliability of the SPAC Method in Urban Areas
2015
We have carried out several long-term measures of seismic noise with triangular arrays of broad-band seismic sensors, to investigate the reliability of the SPAC method in urban areas. We investigate the stationary and anisotropy of the microtremor wave field. We have found that the anisotropy of the microtremor wave field can be evaluated analyzing the HVNSR as function the azimuth. Furthermore, we showed as strong anisotropies in the microtremors are often observable in particular at high frequencies (> 1 Hz). We have verified as microtremors can be difficult to considered as ergodic processes, and for this reason time averaging, also even over a long periods of time, cannot replace an app…
On the stationarity of the horizontal to vertical noise spectral ratio
2015
The Horizontal to Vertical Noise Spectral Ratio (HVNSR) method is nowadays widely used to estimate the resonance frequencies of geological structures. In the HVNSR method, seismic noise is considered as a stationary stochastic process. However, especially in industrialized/urbanized area, this is a very strict assumption seldom occurred. Several sources of noise can generate non stationary and anisotropic microtremor fields. To investigate the stationarity of microtremor, we have carried out several long-term measures of seismic noise with broad-band seismic sensors, in areas where the main source of anthropogenic noise is well known. The signals acquired have been analyzed both in frequenc…
Transcranial Magnetic Resonance Imaging-Guided Focused Ultrasound with a 1.5 Tesla Scanner: A Prospective Intraindividual Comparison Study of Intraop…
2021
Background: High-quality intraoperative imaging is needed for optimal monitoring of patients undergoing transcranial MR-guided Focused Ultrasound (tcMRgFUS) thalamotomy. In this paper, we compare the intraoperative imaging obtained with dedicated FUS-Head coil and standard body radiofrequency coil in tcMRgFUS thalamotomy using 1.5-T MR scanner. Methods: This prospective study included adult patients undergoing tcMRgFUS for treatment of essential tremor. Intraoperative T2-weighted FRFSE sequences were acquired after the last high-energy sonication using a dedicated two-channel FUS-Head (2ch-FUS) coil and body radiofrequency (body-RF) coil. Postoperative follow-ups were performed at 48 h usin…
The INGV's new OBS/H: Analysis of the signals recorded at the Marsili submarine volcano
2009
Abstract The ocean bottom seismometer with hydrophone deployed on the flat top of the Marsili submarine volcano (790 m deep) by the Gibilmanna OBS Lab (CNT–INGV) from 12th to 21st July, 2006, recorded more than 1000 transient seismic signals. Nineteen of these signals were associated with tectonic earthquakes: 1 teleseismic, 8 regional (located by INGV) and 10 small local seismic events (non located earthquakes). The regional events were used to determine sensor orientation. By comparing the signals recorded with typical volcanic seismic activity, we were able to group all the other signals into three categories: 817 volcano–tectonic type B (VT-B) events, 159 occurrences of high frequency t…
The effects of metoclopramide on acetylcholine release and on smooth muscle response in the isolated guinea-pig ileum
1982
The effects of metoclopramide on smooth muscle contraction and on release of acetylcholine were studied in the guinea-pig myenteric plexus longitudinal muscle preparation. Acetylcholine was determined either as endogenous acetylcholine, or as labelled transmitter from strips preloaded with 3H-choline. Metoclopramide caused an increase in resting tension of longitudinal muscle as well as an increase in resting output of either endogenous or labelled acetylcholine. Tetrodotoxin abolished the metoclopramide-evoked increase in transmitter release. The increase in smooth muscle tension was clearly related to the increase in resting output. The effects of metoclopramide on both longitudinal muscl…
Studio di parcellizzazione talamica per l’identificazione del target di trattamento applicato alle talamotomie trans-craniche mediante ultrasuoni foc…
2019
SCOPO DEL LAVORO: La tcMRgFUS consente di effettuare una vera e propria esplorazione neurofunzionale per confermare ed ottimizzare il target lesionale prima di indurre una lesione cerebrale permanente. La scelta del target di trattamento si basa tuttavia su coordinate stereotassiche che non tengono conto delle diversità anatomiche di ciascun individuo. Essendo il paziente vigile durante tutta la durata della procedura, l'ottimizzazione del target di trattamento viene effettuata sulla base del feedback del paziente nel corso della procedura utilizzando sonicazioni di potenza sub-lesionale. Scopo di questo lavoro è valutare retrospettivamente il possibile ruolo della parcellizzazione talamica…