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RESEARCH PRODUCT
Preoperative imaging findings in patients undergoing transcranial magnetic resonance imaging-guided focused ultrasound thalamotomy
Massimo MidiriAntonia PignoloMarco D'amelioRosario MaugeriPatrizia ToiaCesare GagliardoGiorgio ColluraGiuseppe FilorizzoCarlo CatalanoGiuseppe SalvaggioAlessandro NapoliRoberto CannellaGerardo IacopinoTommaso Vincenzo BartolottaMaurizio Marralesubject
Maletranscranial magnetic resonance; thalamotomy; neurological disordersParkinson's diseasemedicine.medical_treatmentneurological disordersNeuropathic paintranscranial magnetic resonance030218 nuclear medicine & medical imaging0302 clinical medicineThalamusMass ScreeningRadiation treatment planningScreening proceduresAged 80 and overeducation.field_of_studyMultidisciplinarymedicine.diagnostic_testSettore MED/27 - NeurochirurgiaQRSettore MED/37 - NeuroradiologiaDisease ManagementMiddle AgedMagnetic Resonance ImagingSurgery Computer-AssistedMedicineStereotaxic TechniqueSettore MED/26 - NeurologiaFemaleRadiologyAdultmedicine.medical_specialtyEssential TremorScienceClinical Decision-MakingPopulationNeuroimagingArticleFocused ultrasoundMultiple sclerosisYoung Adult03 medical and health sciencesComputed TomographyMedical researchParkinson’s Disease.Preoperative CaremedicineHumansInterventional Magnetic Resonance ImagingIn patientMovement disorderseducationHigh-intensity Focused Ultrasound AblationUltrasonography InterventionalAgedThalamotomybusiness.industryMagnetic resonance imagingthalamotomySettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Diseases of the nervous systemSettore MED/36 - Diagnostica Per Immagini E RadioterapiaTomography X-Ray ComputedbusinessMR-guided Focused Ultrasound030217 neurology & neurosurgeryNeurosciencePreoperative imagingdescription
AbstractThe prevalence and impact of imaging findings detected during screening procedures in patients undergoing transcranial MR-guided Focused Ultrasound (tcMRgFUS) thalamotomy for functional neurological disorders has not been assessed yet. This study included 90 patients who fully completed clinical and neuroradiological screenings for tcMRgFUS in a single-center. The presence and location of preoperative imaging findings that could impact the treatment were recorded and classified in three different groups according to their relevance for the eligibility and treatment planning. Furthermore, tcMRgFUS treatments were reviewed to evaluate the number of transducer elements turned off after marking as no pass regions the depicted imaging finding. A total of 146 preoperative imaging findings in 79 (87.8%) patients were detected in the screening population, with a significant correlation with patients’ age (rho = 483, p < 0.001). With regard of the group classification, 119 (81.5%), 26 (17.8%) were classified as group 1 or 2, respectively. One patient had group 3 finding and was considered ineligible. No complications related to the preoperative imaging findings occurred in treated patients. Preoperative neuroradiological findings are frequent in candidates to tcMRgFUS and their identification may require the placement of additional no-pass regions to prevent harmful non-targeted heating.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-01-01 |