Search results for "Thalamotomy"

showing 9 items of 9 documents

Is Transcranial Magnetic Resonance Imaging-Guided Focused Ultrasound a Repeatable Treatment Option? Case Report of a Retreated Patient With Tremor Co…

2019

Introduction In recent years, transcranial Magnetic Resonance Imaging-guided Focused Ultrasound (tcMRgFUS) treatments for functional neurological disorders are giving a new thrust to the field of therapeutic brain lesioning. Objective To present the case of a patient affected by tremor combined with Parkinsonism who underwent a second tcMRgFUS thalamotomy because of relapsing tremor after a few months from the first tcMRgFUS treatment. Methods A 72-yr-old, right-handed man, came to our observation because of a disabling tremor affecting his upper limbs, refusing any invasive surgical procedure and already treated by tcMRgFUS left Vim thalamotomy. However, clinical benefit had brief duration…

Malemedicine.medical_specialtyInterventional magnetic resonance imagingmedicine.medical_treatmentEssential TremorFocused ultrasoundParkinsonian DisordersTremorMedicineHumansAgedmedicine.diagnostic_testbusiness.industryPatient affectedThalamotomySettore MED/27 - NeurochirurgiaParkinsonismSettore FIS/01 - Fisica SperimentaleTreatment optionsSettore MED/37 - NeuroradiologiaMagnetic resonance imagingmedicine.diseaseMagnetic Resonance ImagingTreatment OutcomeStereotaxic techniqueSurgerySettore MED/26 - NeurologiaNeurology (clinical)RadiologyHigh-intensity focused ultrasound ablation Minimally invasive surgical procedures Stereo- taxic techniques Tremor Parkinsonian disorders Interventional magnetic resonance imaging Intraoperative monitoringbusinessSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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Letter: Thalamotomy-Like Effects From Partial Removal of a Ventral Intermediate Nucleus Deep Brain Stimulator Lead in a Patient With Essential Tremor…

2017

Deep Brain StimulationEssential Tremormedicine.medical_treatmentDeep brain stimulator03 medical and health sciences0302 clinical medicineText miningThalamusHumansMedicine030212 general & internal medicineLead (electronics)ThalamuVentral Thalamic NucleiVentral intermediate nucleusEssential tremorSettore MED/27 - Neurochirurgiabusiness.industryThalamotomymedicine.diseasePsychosurgeryAnesthesiaSurgeryNeurology (clinical)businessNeuroscience030217 neurology & neurosurgeryHumanNeurosurgery
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Transcranial magnetic resonance imaging-guided focused ultrasound treatment at 1.5 T: a retrospective study on treatment and patient-related paramete…

2020

Objective: To present a retrospective analysis of patient- and sonication-related parameters of a group of patients treated with a transcranial magnetic resonance imaging (MRI)-guided focused ultrasound (tcMRgFUS) system integrated with a 1.5-T MRI unit. Methods: The data obtained from 59 patients, who underwent the tcMRgFUS procedure from January 2015 to April 2019, were retrospectively reviewed for this study. The following data, among others, were mainly collected: skull density ratio (SDR), skull area (SA), number of available transducer elements (Tx), and estimated focal power at target (FP). For each of the four different treatment stages, we calculated the number of sonication proces…

Interventional magnetic resonance imagingMaterials Science (miscellaneous)medicine.medical_treatmentParkinson's diseaseEssential TremorBiophysicsGeneral Physics and Astronomy01 natural sciencesFocused ultrasound0103 physical sciencesmedicinePlane orientationInterventional Magnetic Resonance ImagingPhysical and Theoretical Chemistry010306 general physicsMathematical Physicsmedicine.diagnostic_testbusiness.industryThalamotomySettore MED/27 - NeurochirurgiaSettore MED/37 - NeuroradiologiaMagnetic resonance imagingRetrospective cohort studystereotaxic techniqueslcsh:QC1-999Settore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Parkinson Disease.essential tremor; high-intensity focused ultrasound ablation; interventional magnetic resonance imaging; Parkinson's disease; stereotaxic techniquesCoronal planeStereotaxic techniqueHigh-Intensity Focused Ultrasound AblationStereotaxic TechniqueSettore MED/26 - NeurologiaNuclear medicinebusinessSettore MED/36 - Diagnostica Per Immagini E Radioterapialcsh:Physics
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Preoperative imaging findings in patients undergoing transcranial magnetic resonance imaging-guided focused ultrasound thalamotomy

2021

AbstractThe prevalence and impact of imaging findings detected during screening procedures in patients undergoing transcranial MR-guided Focused Ultrasound (tcMRgFUS) thalamotomy for functional neurological disorders has not been assessed yet. This study included 90 patients who fully completed clinical and neuroradiological screenings for tcMRgFUS in a single-center. The presence and location of preoperative imaging findings that could impact the treatment were recorded and classified in three different groups according to their relevance for the eligibility and treatment planning. Furthermore, tcMRgFUS treatments were reviewed to evaluate the number of transducer elements turned off after…

Maletranscranial magnetic resonance; thalamotomy; neurological disordersParkinson's diseasemedicine.medical_treatmentneurological disordersNeuropathic paintranscranial magnetic resonance030218 nuclear medicine & medical imaging0302 clinical medicineThalamusMass ScreeningRadiation treatment planningScreening proceduresAged 80 and overeducation.field_of_studyMultidisciplinarymedicine.diagnostic_testSettore MED/27 - NeurochirurgiaQRSettore MED/37 - NeuroradiologiaDisease ManagementMiddle AgedMagnetic Resonance ImagingSurgery Computer-AssistedMedicineStereotaxic TechniqueSettore MED/26 - NeurologiaFemaleRadiologyAdultmedicine.medical_specialtyEssential TremorScienceClinical Decision-MakingPopulationNeuroimagingArticleFocused ultrasoundMultiple sclerosisYoung Adult03 medical and health sciencesComputed TomographyMedical researchParkinson’s Disease.Preoperative CaremedicineHumansInterventional Magnetic Resonance ImagingIn patientMovement disorderseducationHigh-intensity Focused Ultrasound AblationUltrasonography InterventionalAgedThalamotomybusiness.industryMagnetic resonance imagingthalamotomySettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Diseases of the nervous systemSettore MED/36 - Diagnostica Per Immagini E RadioterapiaTomography X-Ray ComputedbusinessMR-guided Focused Ultrasound030217 neurology & neurosurgeryNeurosciencePreoperative imaging
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Transcranial magnetic resonance-guided focused ultrasound thalamotomy as a safe treatment option in multiple sclerosis patients with essential tremor

2020

Transcranial magnetic resonance-guided focused ultrasound is a recently introduced incisionless treating option for essential tremor and tremor-dominant idiopathic Parkinson disease. There is preliminary evidence that it may result in a promising effective treatment option for other movement disorders too. Here, we report on two patients with multiple sclerosis with medication refractory debilitating essential tremor comorbidity who successfully underwent unilateral Vim tcMRgFUS thalamotomy for tremor control. Patients' clinical condition and expanded disability status scale scores showed no changes during the 1-year follow-up period with no evidence of multiple sclerosis activity or progre…

medicine.medical_specialtyNeurologyMovement disordersMagnetic Resonance SpectroscopyMultiple Sclerosismedicine.medical_treatmentEssential TremorDermatologyStereotaxic Techniques03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationThalamusMultiple SclerosimedicineHumansInterventional Magnetic Resonance Imaging030212 general & internal medicineExpanded Disability Status Scalemedicine.diagnostic_testEssential tremorThalamotomybusiness.industrySettore MED/27 - NeurochirurgiaMultiple sclerosisSettore MED/37 - NeuroradiologiaMagnetic resonance imagingGeneral Medicinemedicine.diseaseMagnetic Resonance Imagingnervous system diseasesPsychiatry and Mental healthTreatment OutcomeStereotaxic techniqueHigh-Intensity Focused Ultrasound AblationSettore MED/26 - NeurologiaNeurology (clinical)medicine.symptombusinessSettore MED/36 - Diagnostica Per Immagini E Radioterapia030217 neurology & neurosurgery
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Preliminary experience with a transcranial magnetic resonance-guided focused ultrasound surgery system integrated with a 1.5-T MRI unit in a series o…

2018

OBJECTIVETranscranial magnetic resonance–guided focused ultrasound surgery (tcMRgFUS) is one of the emerging noninvasive technologies for the treatment of neurological disorders such as essential tremor (ET), idiopathic asymmetrical tremor-dominant Parkinson’s disease (PD), and neuropathic pain. In this clinical series the authors present the preliminary results achieved with the world’s first tcMRgFUS system integrated with a 1.5-T MRI unit.METHODSThe authors describe the results of tcMRgFUS in a sample of patients with ET and with PD who underwent the procedure during the period from January 2015 to September 2017. A monolateral ventralis intermedius nucleus (VIM) thalamic ablation was pe…

MaleParkinson's diseaseMovement disordershigh-intensity focused ultrasound ablationIntraoperative Neurophysiological Monitoringmedicine.medical_treatmentinterventional030218 nuclear medicine & medical imagingMagnetic resonance guided focused ultrasound surgery0302 clinical medicineThalamusEssential tremorSettore MED/27 - NeurochirurgiaUltrasoundSettore MED/37 - NeuroradiologiaParkinson DiseaseGeneral MedicineMiddle AgedAblationMagnetic Resonance ImagingTreatment OutcomeNeuropathic painBBB = blood-brain barrier; ET = essential tremor; FRFSE = fast recalled FSE; FSE = fast spin echo; FSPGR = fast spoiled gradient echo; FTM = Fahn-Tolosa-Marin; HI-FU = high-intensity focused ultrasound; MRI; MRgFUS; MS = multiple sclerosis; PD = Parkinson’s disease; Parkinson’s disease; QUEST = Quality of Life in Essential Tremor; SWAN = susceptibility-weighted angiography; UPDRS = Unified Parkinson’s Disease Rating Scale; VIM = ventralis intermedius nucleus; brain; essential tremor; high-intensity focused ultrasound ablation; interventional; magnetic resonance–guided focused ultrasound surgery; stereotactic technique; tcMRgFUS = transcranial magnetic resonance–guided focused ultrasound surgerySettore MED/26 - NeurologiaFemaleRadiologymedicine.symptombrain; essential tremor; high-intensity focused ultrasound ablation; interventional; magnetic resonance-guided focused ultrasound surgery; mrgfus; mri; parkinson's disease; stereotactic techniqueMRIAdultmedicine.medical_specialtybrainEssential Tremormagnetic resonance–guided focused ultrasound surgery03 medical and health sciencesmedicineHumansmagnetic resonance-guided focused ultrasound surgeryUltrasonography InterventionalAgedThalamotomybusiness.industryMRgFUSmedicine.diseasestereotactic techniqueparkinson's diseaseParkinson’s diseaseSurgeryNeurology (clinical)businessSettore MED/36 - Diagnostica Per Immagini E Radioterapia030217 neurology & neurosurgeryFollow-Up StudiesNeurosurgical focus
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Transcranial Magnetic Resonance Imaging-Guided Focused Ultrasound with a 1.5 Tesla Scanner: A Prospective Intraindividual Comparison Study of Intraop…

2021

Background: High-quality intraoperative imaging is needed for optimal monitoring of patients undergoing transcranial MR-guided Focused Ultrasound (tcMRgFUS) thalamotomy. In this paper, we compare the intraoperative imaging obtained with dedicated FUS-Head coil and standard body radiofrequency coil in tcMRgFUS thalamotomy using 1.5-T MR scanner. Methods: This prospective study included adult patients undergoing tcMRgFUS for treatment of essential tremor. Intraoperative T2-weighted FRFSE sequences were acquired after the last high-energy sonication using a dedicated two-channel FUS-Head (2ch-FUS) coil and body radiofrequency (body-RF) coil. Postoperative follow-ups were performed at 48 h usin…

Scannerhigh-intensity focused ultrasound ablationmedicine.medical_treatmentArticleFocused ultrasoundlcsh:RC321-571030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineMcNemar's testmedicinemagnetic resonance imagingimage qualityessential tremorlcsh:Neurosciences. Biological psychiatry. Neuropsychiatrymedicine.diagnostic_testSettore MED/27 - Neurochirurgiabusiness.industryThalamotomyGeneral NeuroscienceMR-guided focused ultrasoundSettore MED/37 - NeuroradiologiaMagnetic resonance imagingstereotaxic techniquesElectromagnetic coilStereotaxic techniquefocused ultrasoundSettore MED/26 - NeurologiaSettore MED/36 - Diagnostica Per Immagini E RadioterapiabusinessNuclear medicine030217 neurology & neurosurgeryRadiofrequency coilBrain Sciences
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Intraoperative imaging findings in transcranial MR imaging-guided focused ultrasound treatment at 1.5T may accurately detect typical lesional finding…

2020

To assess the intraoperative neuroimaging findings in patients treated with transcranial MR-guided focused ultrasound (tcMRgFUS) thalamotomy using 1.5T equipment in comparison with the 48-h follow-up.Fifty prospectively enrolled patients undergoing unilateral tcMRgFUS thalamotomy for either medication-refractory essential tremor (n = 39) or Parkinson tremor (n = 11) were included. Two radiologists evaluated the presence and size of concentric lesional zones (zone I, zone II, and zone III) on 2D T2-weighted sequences acquired intraoperatively after the last high-energy sonication and at 48 h. Sonication parameters including number of sonications, delivered energy, and treatment temperatures …

AdultMalemedicine.medical_specialtyessential tremor; high-intensity focused ultrasound ablation; interventional magnetic resonance imaging; Parkinson disease; stereotaxic techniqueshigh-intensity focused ultrasound ablationInterventional magnetic resonance imagingmedicine.medical_treatmentStereotaxic techniqueSonicationThalamusmedicineHumansRadiology Nuclear Medicine and imagingessential tremorNeuroradiologyAgedUltrasonographyAged 80 and overIntraoperative Caremedicine.diagnostic_testEssential tremorThalamotomybusiness.industryUltrasoundinterventional magnetic resonance imagingSettore MED/37 - NeuroradiologiaInterventional radiologyGeneral Medicinestereotaxic techniquesMiddle Agedmedicine.diseaseMagnetic Resonance ImagingParkinson diseaseCoagulative necrosisSurgery Computer-AssistedStereotaxic techniqueSettore MED/26 - NeurologiaFemaleRadiologySettore MED/36 - Diagnostica Per Immagini E Radioterapiabusiness
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MAGNETIC RESONANCE IMAGING–GUIDED FOCUSED ULTRASOUND THALAMOTOMY IN PATIENT WITH TREMOR COMBINED WITH PARKINSONISM: RETREATMENT AFTER BENEFIT DECAY

2019

Background In recent years, transcranial Magnetic Resonance-guided Focused UltraSounds (tcMRgFUS) treatments for functional neurological disorders are giving a new thrust to the field of therapeutic brain lesioning. This technique has been proven safe and effective in selected patients. Here we present the case of a patient affected by tremor combined with parkinsonism who underwent a second tcMRgFUS thalamotomy because of relapsing tremor after a few months from the first tcMRgFUS treatment. Materials and Methods A 72-year-old, right-handed man, who came to our observation because of a disabling tremor affecting mainly his upper right limb and refusing any invasive surgical procedure. His …

focused ultrasound Parkinsonism thalamotomy thermal ablation retreatemtnSettore MED/27 - NeurochirurgiaSettore MED/37 - NeuroradiologiaSettore MED/26 - NeurologiaSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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