Search results for "Trie"
showing 10 items of 4468 documents
11,12-EET Stimulates the Association of BK Channel α and β1 Subunits in Mitochondria to Induce Pulmonary Vasoconstriction
2012
In the systemic circulation, 11,12-epoxyeicosatrienoic acid (11,12-EET) elicits nitric oxide (NO)- and prostacyclin-independent vascular relaxation, partially through the activation of large conductance Ca(2+)-activated potassium (BK) channels. However, in the lung 11,12-EET contributes to hypoxia-induced pulmonary vasoconstriction. Since pulmonary artery smooth muscle cells also express BK channels, we assessed the consequences of BKβ(1) subunit deletion on pulmonary responsiveness to 11,12-EET as well as to acute hypoxia. In buffer-perfused mouse lungs, hypoxia increased pulmonary artery pressure and this was significantly enhanced in the presence of NO synthase (NOS) and cyclooxygenase (…
Bacheliers professionnels au travail : l'exemple des industries de bien d'équipement
1995
International audience
Understanding the crowdfunding phenomenon and its implications for sustainability
2019
Abstract Nonetheless the large body of knowledge rapidly accumulated on crowdfunding as well as the growing relevance of this phenomenon for sustainability, there are very few studies on the role of crowdfunding for sustainability-oriented projects, and many related issues are still far from being fully understood. This signalises a clear need for unveiling the main dynamics of the relationship between crowdfunding and sustainability, and also opening up useful directions for future research on this relationship. To conceptualize the implications of crowdfunding for sustainability, we propose and use a framework, encompassing five dimensions, namely the project creator, the backers, the cam…
An Easy Assessment of Frailty at Baseline Independently Predicts Prognosis in Very Elderly Patients With Acute Coronary Syndromes.
2017
Background: Information about the impact of frailty in patients with acute coronary syndromes (ACS) is scarce. No study has assessed the prognostic impact of frailty as measured by the FRAIL scale in very elderly patients with ACS. Methods: The prospective multicenter LONGEVO-SCA registry included unselected patients with ACS aged 80 years or older. A comprehensive geriatric assessment was performed during hospitalization, including frailty assessment by the FRAIL scale. The primary endpoint was mortality at 6 months. Results: A total of 532 patients were included. Mean age was 84.3 years, 61.7% male. Most patients had positive troponin levels (84%) and high GRACE risk score values (mean 16…
Bacterial Community Structure of an IFAS-MBRs Wastewater Treatment Plant
2017
TIn this work, the bacterial community putatively involved in BNR events of a UCT-MBMBR pilot plant was elucidated by both culture-dependent and metagenomics DNA analyses. The presence of bacterial isolates belonging to Bacillus (in the anoxic compartment) and to Acinetobacter, Stenotrophomonas, Rhodococcus, Escherichia and Aeromonas (in the aerobic compartment) is in agreement with the nitrification/denitrification processes observed in the plant. Moreover, the study of bacterial community structure by NGS revealed a microbial diversity suggesting a biochemical complexity which can be further explored and exploited to improve UCT-MBMBR plant performance.
The Impact of Family and Work-Life Balance Policies on the Performance of Spanish Listed Companies
2014
Work-life balance has become a topic of great relevance in today's business world. In this work we present both a theoretical review on the state of art in this issue and an analysis testing the validity of the positive impact of work-life balance policies in firm performance. For the empirical analyses of these policies on performance we evaluated a sample composed of firms listed in IBEX-35. Findings provide support for the idea that introducing work-life balance practices benefits the company with respect to talent retention and higher employee engagement, as well as achieving a positive impact on productivity, costs and business results.
The Balanced Scorecard as a Knowledge Management Tool: A French Experience in a Semi-Public Insurance Company
2008
International audience; In this paper we present the Balanced Scorecard, a Strategic Control tool, which is quite famous all around the world and in the European countries. Its principle objective is to articulate planning decisions with control ones thanks to non-financial indicators. The Strategic Control and the Agency Theories constitute the foundation of this tool. But in Northern Europe, some specific Balanced Scorecard have been designed in the framework of the Knowledge Management Theory. To work, the Balanced Scorecard needs a sophisticated information system support. Using two theoretical backgrounds, the Strategic Control approach and the Knowledge Management Theory, we analyse t…
Reemigrācijas attīstība Baltijas valstīs
2016
Migrācija ir nebeidzams pārvietošanās process, gan reģionālā, gan globālā līmenī. Migrācija ietekmē dažādas cilvēku grupas – ekonomiskos migrantus, bez pajumtes palikušās personas, bēgļus (patvēruma meklētājus) un ceļotājus. Migrācija ir daudzslāņains, sarežģīts process, kuru izpētes gaitā nepieciešams skatīt no dažādiem aspektiem, tādēļ, lai gūtu plašāku pārskatu par migrācijas paveida – remigrācijas attīstību Baltijas valstīs, maģistra darbs ir strukturēts divos līmeņos – empīriskais pētījums par trīs Baltijas valstīm – Lietuvu, Latvija un Igauniju un kvalitatīvais pētījums – reemigrācijas attīstība Baltijas valstīs: Latvijas gadījums. Maģistra darba mērķis ir veikt padziļinātu izpēti par…
BlotBase: a northern blot database.
2008
With the availability of high-throughput gene expression analysis, multiple public expression databases emerged, mostly based on microarray expression data. Although these databases are of significant biomedical value, they do hold significant drawbacks, especially concerning the reliability of single gene expression profiles obtained by microarray data. Simultaneously, reliable data on an individual gene's expression are often published as single northern blots in individual publications. These data were not yet available for high-throughput screening. To reduce the gap between high-throughput expression data and individual highly reliable expression data, we designed a novel database "Blo…
Power Grid Integration and Use-Case Study of Acid-Base Flow Battery Technology
2021
There are many different types of energy storage systems (ESS) available and the functionality that they can provide is extensive. However, each of these solutions come with their own set of drawbacks. The acid-base flow battery (ABFB) technology aims to provide a route to a cheap, clean and safe ESS by means of providing a new kind of energy storage technology based on reversible dissociation of water via bipolar electrodialysis. First, the main characteristics of the ABFB technology are described briefly to highlight its main advantages and drawbacks and define the most-competitive use-case scenarios in which the technology could be applied, as well as analyze the particular characteristi…