Search results for "Tying"

Acute activation of cannabinoid receptors by anandamide reduces gastrointestinal motility and improves postprandial glycemia in mice.

2015

International audience; The endocannabinoid system (ECS) is associated with an alteration of glucose homeostasis dependent on cannabinoid receptor-1 (CB1R) activation. However, very little information is available concerning the consequences of ECS activation on intestinal glucose absorption. Mice were injected intraperitoneally with anandamide, an endocannabinoid binding both CB1R and CB2R. We measured plasma glucose and xylose appearance after oral loading, gastrointestinal motility, and glucose transepithelial transport using the everted sac method. Anandamide improved hyperglycemia after oral glucose charge whereas glucose clearance and insulin sensitivity were impaired, pointing out so…

Toward Biopredictive Dissolution for Enteric Coated Dosage Forms

2016

The aim of this work was to develop a phosphate buffer based dissolution method for enteric-coated formulations with improved biopredictivity for fasted conditions. Two commercially available enteric-coated aspirin products were used as model formulations (Aspirin Protect 300 mg, and Walgreens Aspirin 325 mg). The disintegration performance of these products in a physiological 8 mM pH 6.5 bicarbonate buffer (representing the conditions in the proximal small intestine) was used as a standard to optimize the employed phosphate buffer molarity. To account for the fact that a pH and buffer molarity gradient exists along the small intestine, the introduction of such a gradient was proposed for p…

L’armonizzazione europea nella lotta al riciclaggio: un’indagine sullo spazio riservato ai diritti e ai principi del diritto penale

2019

Extending in vitro digestion models to specific human populations: Perspectives, practical tools and bio-relevant information

2017

29th International Conference of the European-Federation-of-Food-Science-and-Technology (EFFoST) -- NOV 10-12, 2015 -- Athens, GREECE

A dynamic model for MED-TVC transient operation

2017

Abstract The Multi Effect Distillation (MED) process is often proposed as a key technology for the construction of new thermal desalination plants, especially within solar-powered cogeneration schemes. With this respect, the need for transient behaviour analysis requires the development of dynamic models for the MED process. Only a few have been presented so far in the literature, in which, however, several simplifying assumptions and constrains are still limiting their potential use. The model here proposed addresses most of the aspects still limiting previous models formulations. The powerful equation-based process simulator gPROMS® was chosen for the implementation of the model, develope…

Italy: money transfer, money laundering and intermediary liability

2020

Purpose This paper aims to offer a general overview of money transfers in Italy and Europe focussing specifically on the migrant community. This is of particular interest because it is in that community where money transfers are most prevalent. This shows the money transfer system as a tool that could guarantee the financial inclusion of migrants but at the same time being used in a distorted and unlawful manner. Design/methodology/approach After a brief introduction focussed on working principles and legal frameworks, the paper will go deeper in evaluating money transfer data. This data, which comes from various legal authorities, will show the extent to which different migrant communitie…

Einfluß der Nahrungsaufnahme auf die Magenentleerung magensaftresistenter Tabletten und Kapseln*

2008

To test the effect of food intake on gastric emptying of gastric juice-resistant drugs, emptying time of a 11 x 6 mm tablet and a 20 x 7 mm capsule was measured by means of a metal detector in 10 healthy persons (5 men and 5 women; mean age 25 [18-30] years) after fasting and after eating three main and three in-between meals. After fasting the tablets left the stomach after 78 +/- 18 min, the capsules after 60 +/- 16 min, while meal intake delayed emptying by a factor of 10 to 12 +/- 1.3 hours and 10 +/- 1.8 hours, respectively. The slightly shorter emptying time of capsules was statistically not significant. The results indicate that gastric juice-resistant tablets taken during day-time m…

Gastric emptying in infants with gastroesophageal reflux Ultrasound evaluation before and after cisapride administration

1992

The present study aimed to evaluate gastric emptying in children with gastroesophageal reflux (GER) by means of real-time ultrasonography, on the basis of measurements of the cross-sectional area of the gastric antrum. Twelve children with GER were studied (seven males, five females; age range, 3-13 months) and compared with 12 normal control children (six males, six females; age range, 3-13 months). The diagnosis of GER was confirmed by 24-h esophageal pH-monitoring. The GER patients had a significantly greater antral area than the controls at 90, 105, and 120 min aftereating a standard meal (cow's milk formula, 300 ml/m2 body surface area); in addition, final gastric emptying time was sig…

Magenentleerung nach Magenresektion mit und ohne erhaltene Duodenalpassage

1991

Bei Hausschweinen wurden 2/3-Magenresektionen mit erhaltener sowie ausgeschalteter Duodenalpassage durchgefuhrt, die Magenentleerung szintigraphisch uber 4 h gemessen und einer Vergleichsgruppe nichtresezierter Tiere gegenubergestellt. Fur die halbfeste, mit 99mTc markierte Testmahlzeit fanden sich experimentell keine Hinweise fur eine verzogerte Magenentleerung nach Ausschaltung der Duodenalpassage durch Roux-Rekonstruktion. B-I- and B-II-Roux-Resektion differierten in der Magenentleerung nicht. Die Langenanderung der bei der Roux-Rekonstruktion verwendeten Jejunumschlinge von 40 auf 20 cm hatte keinen Einflus auf die Magenentleerung. Die Roux-Rekonstruktion mit trunkularer Vagotomie fuhrt…

The Post-entrepreneurial University: The Case for Resilience in Higher Education

2021

AbstractHistorically speaking, the university has been a highly resilient organizational form; however recent pressures to become entrepreneurial threaten the institutional foundations on which that reliance is based. The chapter first provides conceptual clarity by revisiting what we argue are two distinct schools of thought on the entrepreneurial university. We show how the economic school’s conception intertwines with the rise of New Public Management (NPM) in Europe in the late 1990s and early 2000s, reframing the concept in ways that made it incompatible with resilience thinking. However, we argue that by tying back into ‘lost’ elements of sociological school’s conception, and associat…