Search results for "Type"

A Pilot Study on Developing Newsgames in Collaboration between Journalism and Computer Science Students

2019

Abstract Producing digital and interactive journalistic products offers unique and important new learning opportunities for journalism education. This study analysed the experiences of two pilot courses on so-called ‘newsgames’ in a Finnish university in 2015 and 2017. The data consisted of the newsgames and other materials produced by the students, student feedback concerning the course and observations of teachers throughout the project. Our analysis demonstrates how producing newsgames in the context of higher education may foster project-based learning experiences, something that has been relatively rare in traditional journalism education. Collaboration with media companies also offere…

Behavior regulations and motives to participate in physical activity of Finnish team sports athletes

2014

The study examined the motivation to participate and behavior regulation in team sports among Finnish athletes. It explored differences across gender and among various team sport types. One hundred and seventy five girls and 142 boys (aged 12 to 24 years old) participated in the study. Motives to participate were measured on the Physical Activity and Leisure Motivation Scale (PALMS, Morris & Rogers, 2004), while behavior regulations were measured on the Behavior Regulation in Sport Questionnaire (BRSQ, Lonsdale, Hodge & Rose, 2008). Others' expectation was excluded from calculations due to low reliability. Participants scored higher on mastery, enjoyment and physical condition in PALMS scal…

The motivational values of social entrepreneurs

2015

The main goal of this research is to understand what kind of motivational values social entrepreneurs have (motivational types of values), how social entrepreneurs prioritize these values (value prioritization) and if these values had an impact on becoming a social entrepreneur and continuing to work as one (impact of the values). The research on social entrepreneurship has largely ignored for-profit social entrepreneurship and the purpose of this research is to contribute to this shortcoming by taking the for-profit entrepreneurs’ perspective. A qualitative case study was chosen as a research method and the empirical data was gathered by interviewing for-profit social entrepreneurs using a…

Motywacje do nauki języka ukraińskiego studentów filologii rosyjskiej Uniwersytetu Opolskiego

2010

Motywacje do nauki języka ukraińskiego wśród studentów filologii rosyjskiej Uniwersytetu Opolskiego zostały zbadane na podstawie przeprowadzonej ankiety. Zadaniem ankietera było określenie, jakie funkcjonuje nastawienie wśród studentów i czy istnieje chęć do nauki języka ukraińskiego. Następnie określono motywacje do nauki tego języka. Badania dowiodły, że studenci wykazują zainteresowanie nauką języka ukraińskiego, jak również wskazują na konkretne motywacje do nauki oraz są skłonni je wprowadzić do procesu przyswajania wiedzy. Wśród motywacji wskazują m.in., że język ukraiński jest – potrzebny w przyszłości, ciekawy i potrzebny już teraz oraz, że lektorat języka ukraińskiego jest dobrym u…

A visualization technique for accessing solution pool in interactive methods of multiobjective optimization

2015

<pre>Interactive methods of <span>multiobjective</span> optimization repetitively derive <span>Pareto</span> optimal solutions based on decision maker's preference information and present the obtained solutions for his/her consideration. Some interactive methods save the obtained solutions into a solution pool and, at each iteration, allow the decision maker considering any of solutions obtained earlier. This feature contributes to the flexibility of exploring the <span>Pareto</span> optimal set and learning about the optimization problem. However, in the case of many objective functions, the accumulation of derived solutions makes accessing the sol…

Genome-wide analysis of Italian sheep diversity reveals a strong geographic pattern and cryptic relationships between breeds

2014

Summary Italy counts several sheep breeds, arisen over centuries as a consequence of ancient and recent genetic and demographic events. To finely reconstruct genetic structure and relationships between Italian sheep, 496 subjects from 19 breeds were typed at 50K single nucleotide polymorphism loci. A subset of foreign breeds from the Sheep HapMap dataset was also included in the analyses. Genetic distances (as visualized either in a network or in a multidimensional scaling analysis of identical by state distances) closely reflected geographic proximity between breeds, with a clear north–south gradient, likely because of high levels of past gene flow and admixture all along the peninsula. Sa…

Multipoint transmission scheme for HSDPA

2013

Myostatin/activin blocking combined with exercise reconditions skeletal muscle expression profile of mdx mice

2015

Duchenne Muscular Dystrophy is characterized by muscle wasting and decreased aerobic metabolism. Exercise and blocking of myostatin/activin signaling may independently or combined counteract muscle wasting and dystrophies. The effects of myostatin/activin blocking using soluble activin receptor-Fc (sActRIIB-Fc) administration and wheel running were tested alone or in combination for seven weeks in dystrophic mdx mice. Expression microarray analysis revealed decreased aerobic metabolism in the gastrocnemius muscle of mdx mice compared to healthy mice. This was not due to reduced home-cage physical activity, and was further downregulated upon sActRIIB-Fc treatment in enlarged muscles. However…

Derepressing muscleblind expression by miRNA sponges ameliorates myotonic dystrophy-like phenotypes in Drosophila

2016

AbstractMyotonic Dystrophy type 1 (DM1) originates from alleles of the DMPK gene with hundreds of extra CTG repeats in the 3′ untranslated region (3′ UTR). CUG repeat RNAs accumulate in foci that sequester Muscleblind-like (MBNL) proteins away from their functional target transcripts. Endogenous upregulation of MBNL proteins is, thus, a potential therapeutic approach to DM1. Here we identify two miRNAs, dme-miR-277 and dme-miR-304, that differentially regulate muscleblind RNA isoforms in miRNA sensor constructs. We also show that their sequestration by sponge constructs derepresses endogenous muscleblind not only in a wild type background but also in a DM1 Drosophila model expressing non-co…

miR-7 Restores Phenotypes in Myotonic Dystrophy Muscle Cells by Repressing Hyperactivated Autophagy

2019

International audience; Unstable CTG expansions in the 3' UTR of the DMPK gene are responsible for myotonic dystrophy type 1 (DM1) condition. Muscle dysfunction is one of the main contributors to DM1 mortality and morbidity. Pathways by which mutant DMPK trigger muscle defects, however, are not fully understood. We previously reported that miR-7 was downregulated in a DM1 Drosophila model and in biopsies from patients. Here, using DM1 and normal muscle cells, we investigated whether miR-7 contributes to the muscle phenotype by studying the consequences of replenishing or blocking miR-7, respectively. Restoration of miR-7 with agomiR-7 was sufficient to rescue DM1 myoblast fusion defects and…