Search results for "Ultra"

The combined effect of fludarabine monophosphate and radiation as well as gemcitabine and radiation on squamous carcinoma tumor cell lines in vitro.

2008

Despite proven antitumor activity of gemcitabine in chemoradiotherapy of advanced head and neck cancer, many authors refer to severe acute and late local and haematological toxicity. Fludarabine does imply nearly the same mechanisms of action as gemcitabine, inhibiting various enzymes involved in DNA replication. This investigation focuses on the combined effect of either fludarabine or gemcitabine and radiation on human squamous carcinoma cell lines in vitro, providing data for future decisions on head and neck chemoradiotherapy regimen.ZMK-1, A549, BW-225, GR-145, OH-65 and CaSki cell lines were incubated with either drug at defined schedules and irradiated at a single fraction dose of 2 …

Transparent boundary condition for acoustic propagation in lined guide with mean flow

2008

A finite element analysis of acoustic radiation in an infinite lined guide with mean flow is studied. In order to bound the domain, transparent boundary conditions are introduced by means of a Dirichlet to Neumann (DtN) operator based on a modal decomposition. This decomposition is easy to carry out in a hard‐walled guide. With absorbant lining, many difficulties occur even without mean flow. Since the eigenvalue problem is no longer selfadjoint, acoustic modes are not orthogonal with respect to the L2‐scalar product. However, an orthogonality relation exists which permits writing the modal decomposition. For a lined guide with uniform mean flow, modes are no longer orthogonal but a new sca…

Coloboma retinocoroideo: estudio mediante retinografía, angiografía fluoresceínica, ecografía y tomografía de coherencia óptica

2018

Focused Ultrasound in Neuroscience. State of the Art and Future Perspectives

2021

Transcranial MR-guided Focused ultrasound (tcMRgFUS) is a surgical procedure that adopts focused ultrasounds beam towards a specific therapeutic target through the intact skull. The convergence of focused ultrasound beams onto the target produces tissue effects through released energy. Regarding neurosurgical applications, tcMRgFUS has been successfully adopted as a non-invasive procedure for ablative purposes such as thalamotomy, pallidotomy, and subthalamotomy for movement disorders. Several studies confirmed the effectiveness of tcMRgFUS in the treatment of several neurological conditions, ranging from motor disorders to psychiatric disorders. Moreover, using low-frequencies tcMRgFUS sys…

Amplifier similariton fibre laser with nonlinear spectral compression

2012

We propose and numerically demonstrate a new concept of fibre laser architecture supporting self-similar pulse evolution in the amplifier and nonlinear pulse spectral compression in the passive fibre. The latter process is beneficial for improving the power efficiency as it prevents strong spectral filtering from being highly dissipative.

Highly-chirped similaritons generation from a mode-locked fiber laser

2007

In this communication, we report experimental and numerical results on dynamics and propagation of self-similar pulses in a passively mode-locked ytterbium doped DC fiber laser.

Ultrafast Gain Recovery in Quantum Dot based Semiconductor Optical Amplifiers

2007

Summary form only given. The limiting factor in ultrahigh bit rate amplification is the ultrafast population recovery in the resonant level, which is mainly limited by carrier capture and relaxation processes in the QD. We use pump-probe measurements resonant to the QDs confined states energies (ground and excited state) to investigate the response to a four fs-pulse train of 1 THz repetition rate. A deep insight about the capture process implied is then obtained, and direct capture from the wetting layer is identified as the dominant mechanism in the high current regime.

Linear and nonlinear fiber propagation of partially coherent fields exhibiting temporal correlations

2019

International audience; Using ultrafast photonic first-order differentiator applied on a partially coherent field, we report the generation of two correlated temporal waveforms and study their correlation properties upon linear and nonlinear propagation along the two orthogonal polarization axis of a dispersive optical fiber. Temporal correlations are maintained in linear propagation whereas Kerr nonlinearity generates anti-correlated temporal intensity patterns for both partially and uncorrelated fields. Experiments are in close agreement with the theoretical analysis.

A Computational Study on Temperature Variations in MRgFUS Treatments Using PRF Thermometry Techniques and Optical Probes

2021

Structural and metabolic imaging are fundamental for diagnosis, treatment and follow-up in oncology. Beyond the well-established diagnostic imaging applications, ultrasounds are currently emerging in the clinical practice as a noninvasive technology for therapy. Indeed, the sound waves can be used to increase the temperature inside the target solid tumors, leading to apoptosis or necrosis of neoplastic tissues. The Magnetic resonance-guided focused ultrasound surgery (MRgFUS) technology represents a valid application of this ultrasound property, mainly used in oncology and neurology. In this paper

Spatial beam self-cleaning in multimode fibres

2017

Multimode optical fibres are enjoying a renewed attention, boosted by the urgent need to overcome the current capacity crunch of single-mode fibre systems and by recent advances in multimode complex nonlinear optics [1-13]. In this work, we demonstrate that standard multimode fibres can be used as ultrafast all-optical tool for transverse beam manipulation of high power laser pulses. Our experimental data show that the Kerr effect in a graded-index multimode fibre is the driving mechanism for overcoming speckle distortions, leading to a somewhat counter-intuitive effect resulting in a spatially clean output beam robust against fibre bending. Our observations demonstrate that nonlinear beam …