Search results for "Unity"

TLR2, but not TLR4, triggers cytokine production by murine cells in response to Candida albicans yeasts and hyphae.

2006

Toll-like receptors (TLRs) function as sensors for infection that induce the activation of the immune responses. Recent studies have demonstrated a crucial involvement of TLRs in the recognition of fungal pathogens such as Candida albicans. Although both TLR2 and TLR4 have been implicated in the host interaction with C. albicans, their specific role during infection has not been unequivocally established, as conflicting results have been reported. In this review, we summarize and discuss our own and others' key findings about the specific role of TLR2 and TLR4 in murine resistance to candidiasis, and in triggering cytokine secretion by murine cells in response to C. albicans yeasts and hyph…

Ecological aspects of plants inhabiting Mediterranean cliffs. Challenges and prospects of life in vertical environments

2021

[ES] Esta tesis investiga las oportunidades, desafíos y limitaciones para la investigación en el campo de la ecología vegetal, en el contexto de los acantilados mediterráneos. En concreto, las especies casmofiticas, cuyos hábitats naturales se caracterizan por su acusada pendiente. Las laderas de las montañas de piedra caliza en la proximidad del mar, en la parte central y occidental del área mediterránea se consideran objetos de estudio. Los estudios se llevaron a cabo en los cinturones costeros de montaña de las costas del noroeste de Sicilia y la costa diánica en la Comunidad Valenciana. El primer capítulo, titulado "The complexity of environmental factors: cliff microclimate", investiga…

Novedades y consideraciones sobre el género Centaurea L. en la flora valenciana

2008

Se realizan algunas reflexiones sobre las especies valencianotarraconenses de Centaurea sect. Willkommia, grupo que actualmente está conformado por seis táxones en dicho territorio. A partir del estudio de numeroso material que cubre la mitad norte de la provincia de Valencia y la totalidad de Castellón, se revisan dichos táxones y se realiza una nueva propuesta en la que se describen dos nuevas especies: C. aguilellae (de las comarcas del centro-norte de Valencia) y C. fabregatii (de las comarcas del centro-este de Castellón). Novelties and considerations on Centaurea L. concerning the Valencian flora (eastern Spain): Data are reported on the Valencian-Tarraconensian (E of Spain) species o…

Mobilteknologi til videokommunikasjon ved trygghetsalarmer

2007

Masteroppgave i informasjons- og kommunikasjonsteknologi 2007 – Høgskolen i Agder, Grimstad Denne rapporten behandler bruk av mobiltelefoner som alarmsentral for hjemmeboende brukere. Studien legger vekt på de forskjellige mobile netts egenskaper og begrensninger som alarmbefordrer. Ønske om videotelefoni som alarm behandles og det foreslås løsninger for å ivareta dette uten å gå på akkord med sikkerhet. Juridiske sider med alarmer og videobilder behandles ut fra to ulike scenario avhengig av om hjelpere er offentlige eller private. Studien er gitt som en del av interregIII prosjektet Grensebroen Arena sin satsning innen emnet “Et år til hjemme” rettet mot eldre hjemme- boende. Prosjektet h…

Immune effects of 5-fluorouracil

2012

Cytotoxic anticancer drugs can promote antitumor immune responses. The anticancer activity of 5-fluorouracil (5FU) relies on the restoration of T-cell immunity following the elimination of myeloid-derived suppressor cells (MDSCs). We have recently discovered that the 5FU-driven activation of the NLRP3 inflammasome in MDSCs promotes tumor angiogenesis by eliciting TH17 responses that compromise anticancer immunity. This underscores the need to combine 5-FU with NLRP3 inhibitors to prevent tumor progression.

Towards chemical communication between gated nanoparticles.

2014

The design of comparatively simple and modularly configurable artificial systems able to communicate through the exchange of chemical messengers is, to the best of our knowledge, an unexplored field. As a proof-of-concept, we present here a family of nanoparticles that have been designed to communicate with one another in a hierarchical manner. The concept involves the use of capped mesoporous silica supports in which the messenger delivered by a first type of gated nanoparticle is used to open a second type of nanoparticle, which delivers another messenger that opens a third group of gated nanoobjects.We believe that the conceptual idea that nanodevices can be designed to communicate with …

COGNITIVE MOBILIZATION IN PLANNING CONFLICT. Values and democratic implications in two southern-Europe insurgent practices.

La tesi sostiene che, mentre molte teorie di pianificazione si sono concentrate sulle differenze, il multiculturalismo e risoluzione dei conflitti sociali, non c'è ancora sufficiente approfondimento su come queste differenze possano restare profondamente irrisolte e come questa debolezza possa essere fortemente legata a razionalità contrastanti e a una sorta di “slittamento dei livelli di senso” o “equivoci” cognitivi tra i soggetti coinvolti (Bourdieu e Wacquant, 1992). Soprattutto in termini di conflitti urbani espliciti, generati non da opposti interessi economici o differenti volontà politiche, ma semplicemente da differenti background culturali e comportamentali, il livello cognitivo d…

Associations between parental rules, style of communication and children's screen time

2015

Background Research suggests an inverse association between parental rules and screen time in pre-adolescents, and that parents’ style of communication with their children is related to the children’s time spent watching TV. The aims of this study were to examine associations of parental rules and parental style of communication with children’s screen time and perceived excessive screen time in five European countries. Methods UP4FUN was a multi-centre, cluster randomised controlled trial with pre- and post-test measurements in each of five countries; Belgium, Germany, Greece, Hungary and Norway. Questionnaires were completed by the children at school and the parent questionnaire was brough…

Jifo spēles programmēšana

2015

Šajā kvalifikācijas darbā ir aprakstīta 2D puzles veida spēle radīta iericem ar dažādām operētājsistēmam(Windows,IOS,Android).Spēle piedāvā vairākus līmeņus ar vairākiem pretiniekiem un dažādiem speles elementiem piedavajot mainīgu sarežģītības pakāpes lidz ko spēle progresē. Tā kā spēles grafiskio daļu izmeri ir diezgan lieli speles izmers lidz ar to ir liels un spēle parstaj darboties uz vecākām iericēm kurmam nav pietiekami RAM atmiņas.Sakumā spēle bija paredzēta tikai Ipad, bet spēle ir izveidota, lai ta darbotos uz iepriekš minētajam operētājsistēmam. Spēle izveidota C# programmēšanas valodā, Unity vidē.(izmantojot tā dzinuli)

Humoral Mechanisms in T cell Vaccination: Induction and Functional Characterization of Anti-lymphocytic Autoantibodies

1997

T cell vaccination, the application of syngeneic attenuated T cells, has been shown to prevent effectively and treat experimental autoimmune diseases, but its mechanisms of action are poorly understood. Here we present data on the induction of a humoral anti-T cell response by T cell vaccination, capable of strongly inhibiting T cell proliferation and of ameliorating experimental autoimmune disease. T cell vaccination in the Lewis rat induced autoantibodies reactive with several syngeneic T cell proteins. These autoantibodies were not detectable in normal Lewis sera as assessed by immunoblotting and flow cytometry with intact syngeneic T cells. The autoantibody reactivity was not restricted…