Search results for "Unity"
showing 10 items of 3852 documents
Mannheimer Innovationspanel (MIP), Scientific-Use-Files der Jahre 1993-2016
2018
Das ZEW erhebt seit 1993 jährlich Daten zum Innovationsverhalten der deutschen Wirtschaft. Die Innovationserhebung deckt die Bereiche Bergbau, verarbeitendes Gewerbe, Energie, Baugewerbe, unternehmensnahe Dienstleistungen und distributive Dienstleistungen ab. Sie ist für Deutschland repräsentativ und ermöglicht Hochrechnung für die deutsche Wirtschaft insgesamt sowie für einzelne Branchengruppen. Es wird im Auftrag des BMBF und in Kooperation mit infas und dem Fraunhofer-ISI durchgeführt. Das MIP ist gleichzeitig der deutsche Beitrag zu den Community Innovation Surveys (CIS) der Europäischen Kommission. Die jährliche Innovationserhebung ist als Panelbefragung konzipiert. Dabei werden jedes …
Mannheimer Innovationspanel (MIP), Scientific-Use-Files der Jahre 1993-2014
2018
Das ZEW erhebt seit 1993 jährlich Daten zum Innovationsverhalten der deutschen Wirtschaft. Die Innovationserhebung deckt die Bereiche Bergbau, verarbeitendes Gewerbe, Energie, Baugewerbe, unternehmensnahe Dienstleistungen und distributive Dienstleistungen ab. Sie ist für Deutschland repräsentativ und ermöglicht Hochrechnung für die deutsche Wirtschaft insgesamt sowie für einzelne Branchengruppen. Es wird im Auftrag des BMBF und in Kooperation mit infas und dem Fraunhofer-ISI durchgeführt. Das MIP ist gleichzeitig der deutsche Beitrag zu den Community Innovation Surveys (CIS) der Europäischen Kommission. Die jährliche Innovationserhebung ist als Panelbefragung konzipiert. Dabei werden jedes …
Evolution, adaptation and immune functions of fish F-type lectins. The novelty of FBL from Trematomus bernacchii (Boulenger, 1902)
2020
Lectins are a protein family, present in almost all living organisms and involved in different biological pathways, such as immune responses. The Fucose Binding Lectin (FBL), constitute the latest lectin family identified and characterized in fishes. The FBL family is constituted by a large number of proteins exhibiting multiples of the F-type motif, either tandemly arrayed or in mosaic combinations with other domains. In an early step a FBL has been isolated and characterized from serum of the Antarctic fish Trematomus bernacchii by affinity chromatography on fucose-agarose column. A clear Bacterial agglutinating activity (BA) towards different bacteria strains (Escherichia coli, Kokuria r…
T Cell Large Granular Lymphocytic Leukemia in Association with Sjögren’s Syndrome
2009
T cell large granular lymphocytic (LGL) leukemia is a rare condition accounting for 2–3% of all mature lymphoid leukemias. Here, we present the case of a 73-year-old woman presenting with neutropenia and anemia (hemoglobin 9.9 g/dl). Hematological assessment revealed the presence of a T cell LGL leukemia. At the time of T cell LGL leukemia diagnosis, the patient developed xerophthalmia and xerostomia, and a diagnosis of Sjögren’s syndrome was made following salivary gland biopsy. The finding of large granular lymphocytes in the context of autoimmune disorders is well-known, though it often occurs with rheumatoid arthritis or in association with a positive autoantibody titer in the absence o…
Transcriptomic and Bioinformatic Analyses Identifying a Central Mif-Cop9-Nf-kB Signaling Network in Innate Immunity Response of Ciona robusta
2023
The Ascidian C. robusta is a powerful model for studying innate immunity. LPS induction activates inflammatory-like reactions in the pharynx and the expression of several innate immune genes in granulocyte hemocytes such as cytokines, for instance, macrophage migration inhibitory factors (CrMifs). This leads to intracellular signaling involving the Nf-kB signaling cascade that triggers downstream pro-inflammatory gene expression. In mammals, the COP9 (Constitutive photomorphogenesis 9) signalosome (CSN) complex also results in the activation of the NF-kB pathway. It is a highly conserved complex in vertebrates, mainly engaged in proteasome degradation which is essential for maintaining proc…
Autoantibody detection using indirect immunofluorescence on HEp-2 cells
2009
The detection of autoantibodies is an important element in the diagnosis and monitoring of disease progression in patients with autoimmune diseases. In laboratory diagnostic tests for connective tissue and autoimmune liver diseases, indirect immunofluorescence on HEp-2 cells plays a central role in a multistage diagnostic process. Despite the high quality of diagnostics, findings at different laboratories can differ considerably due to a lack of standardization, as well as subjective factors. The present paper formulates recommendations for the standardized processing and interpretation of the HEp-2 cell test for the detection of non-organ-specific (especially antinuclear) antibodies. It pr…
Immune-neuroendocrine biology of invertebrates: a collection of methods
2008
In the last decade there has been a considerable increase of interest towards the elucidation of several aspects of invertebrate biology, including immunity and neuroendocrinology. However, due to the difficulties connected to the great variety of morphology and adaptations displayed by invertebrates, and also in consideration of the number of techniques that are applied in the various laboratories, research on invertebrates still suffers from hampering that have been substantially overcome in vertebrate models, especially in mammals. The aim of this Technical Report is to provide the reader a useful list of well-established morphological and morpho-functional protocols in order to facilita…
Household skills and low wages
2008
Originally published in the journal Journal of Population Economics, Springer http://www.springerlink.com/content/100520/ Household skills provide job skills when tasks in jobs and household production are similar and jobs produce substitutes for home-made services. Opportunity costs of higher education are foregone earnings during schooling and foregone household production while studying and later in life. I show that individuals in jobs requiring household skills accept lower wage rates than traditional human capital theory predicts, and that individuals with low household skills tend to enter higher education. According to these results, declining household skills may have contributed t…
What Makes for Fair Schooling?
2007
Slogans calling for “une ecole juste” (fair schooling) are often as vague as they are effective in mobilising public opinion: though there is apparent agreement on the desirability of greater fairness in education, the matter of defining fair schooling parameters is extremely complex and riddled with ambiguity.
Jāzeps Rancāns un uzsaukums vēlēšanām Eslingenē
2021
Raksts satur informāciju par Latvijas Universitātes Muzeja LU vēstures kolekcijas krājumā esošo Latvijas Centrālās padomes locekļa Jāzepa Rancāna vēlēšanu uzsaukumu Eslingenes latviešiem, kuri nonāca trimdā sakarā ar otrreizējo PSRS okupāciju pēc Otrā pasaules kara. Blakus Eslingenes vēlēšanu uzsaukuma analīzei tiek analizēt arī paša J. Rancāna personības loma Latvijas valsts un LU vēsturē, sasaistot ar Romas katoļu baznīcas lomu Latvijas politiskajā un sabiedriskajā dzīvē.