Search results for "VALUATION"

Quantitative determination of casein genetic variants in goat milk: Application in Girgentana dairy goat breed

2016

The study was conducted to develop a high-performance liquid chromatographic (HPLC) method to quantify casein genetic variants (αs2-, β-, and κ-casein) in milk of homozygous individuals of Girgentana goat breed. For calibration experiments, pure genetic variants were extracted from individual milk samples of animals with known genotypes. The described HPLC approach was precise, accurate and highly suitable for quantification of goat casein genetic variants of homozygous individuals. The amount of each casein per allele was: αs2-casein A = 2.9 ± 0.8 g/L and F = 1.8 ± 0.4 g/L; β-casein C = 3.0 ± 0.8 g/L and C1 = 2.0 ± 0.7 g/L and κ-casein A = 1.6 ± 0.3 g/L and B = 1.1 ± 0.2 g/L. A good correl…

Diagnostic therapeutic flow-charts for low-back pain patient : the Italian clinical guidelines

2006

Revista electrónica de investigación y evaluación educativa

2014

Resumen basado en el de la publicación Título, resumen y palabras clave en inglés y español Se pretende realizar inferencias sobre el campo de la Evaluación de Programas Educativos (E.P.E.), sintetizando ciertos patrones relativos a la metodología de sus investigaciones. En concreto, sobre el paradigma de fundamentación epistemológica, la metodología de investigación específica, el modelo evaluativo empleado, las técnicas de muestreo, los instrumentos empleados para la recogida de información y las técnicas de análisis de datos, el diseños de investigación, las amenazas a su validez, los agentes evaluadores y otras características metodológicas consideradas. Para ello, se revisaron 208 trab…

Peut-on parler de recherche en pédagogie universitaire, aujourd’hui, en France ?

2009

Définir la pédagogie universitaire et savoir ce qu’elle recouvre en France en termes de recherche constitue un enjeu. En effet, le manque de visibilité et de lisibilité de ce champ en limitent probablement la portée à l’heure où la notion de qualité semble se faire plus pressante dans le contexte universitaire français. En partant d’une définition opérationnelle de ce que l’on peut entendre par pédagogie universitaire en France et en s’appuyant sur une recherche documentaire effectuée à partir de la base de données Francis ainsi que de la consultation de programmes complets de différents colloques, cet article vise à mettre en perspective et à illustrer les principaux axes de recherche qui …

Promoting Research and Landscape Experience in the Management of the Archaeological Networks. A Project-Valuation Experiment in Italy

2020

Archaeological sites are part of the history and identity of a community playing a strategic role on the different scales of the cultural and economic common life. Whereas on the one end the most famous archaeological sites attract huge flows of tourists and investment, on the other hand, many minor archaeological sites remain almost ignored and neglected. This study proposes a project-evaluation approach devoted to the &ldquo

Towards high-accuracy mass spectrometry of highly charged short-lived ions at ISOLTRAP

2006

Dedicated to H.-J. Kluge on the occasion of his 65th birthday anniversary - Jürgen Kluge Special Issue; Multiply charged ions of stable xenon isotopes from a plasma ion source have been mass-selected by the on-line mass separator ISOLDE/CERN and delivered to the triple-trap mass spectrometer ISOLTRAP. The doubly charged ions that survived the charge-exchange processes during bunching and ion preparation were transferred to a precision Penning trap for mass determination. Mass values were obtained for the isotopes with mass numbers A=126,129,130,136. They are consistent with previous results except for the case of $^{126}Xe$ where a significant deviation from the literature value was found. …

1H-NMR-Based Metabolomics in Autism Spectrum Disorder and Pediatric Acute-Onset Neuropsychiatric Syndrome

2022

We recently described a unique plasma metabolite profile in subjects with pediatric acute-onset neuropsychiatric syndrome (PANS), suggesting pathogenic models involving specific patterns of neurotransmission, neuroinflammation, and oxidative stress. Here, we extend the analysis to a group of patients with autism spectrum disorder (ASD), as a consensus has recently emerged around its immune-mediated pathophysiology with a widespread involvement of brain networks. This observational case-control study enrolled patients referred for PANS and ASD from June 2019 to May 2020, as well as neurotypical age and gender-matched control subjects. Thirty-four PANS outpatients, fifteen ASD outpatients, an…

Scientific journals on Education in Spain: evolution and prospects for the future

2014

The Spanish scientific journals on education have experience an exponential growth in recent decades. The reasons are closely related to the supranational policies of university quality assessment, with specific emphasis on research output with "impact". This way, in just twenty years, Spanish journals have become, in detriment of books, in the main channel of communication of the also increasing educational research. In an extremely competitive global context, dominated by Anglo-Saxon culture, the Spanish journals have made a significant improvement in the quality of editorial management processes, in accordance with international quality indicators. However, access to the most recognized …

Serveur Calliope : bibliothèque virtuelle

1996

Rapport d'expertise; Evaluation par inspection et test utilisateur d'une bibliothèque virtuelle. Ce travail a été réalisé lors d'observations pratiquées sur le serveur CALLIOPE à partir du mois de juin 1996. Il s'agit d'une évaluation de type «évaluation experte» qui consiste à comparer les performances d'un système aux recommandations ou standards existants. Nous avons utilisé les «critères ergonomiques» de Bastien J.M.C. & Scapin D.L. (INRIA) . Nous avons également vérifié auprès de différents types d'utilisateurs qui n'avaient jamais utilisé Calliope la facilité d'utilisation de certaines fonctions. Nous avons choisi pour ce faire 4 utilisateurs à qui nous avons demandé de consulter la b…

A frozen analogue approach to aminopyridinylimidazoles leading to novel and promising p38 MAP kinase inhibitors.

2012

In this study we report the design, synthesis, and biological evaluation of constrained aminopyridinylimidazoles as p38α MAP kinase inhibitors. The frozen analogue approach focused on the pyridinyl unit, using purine bioisosteres as constrained structure analogues. The identification of the most potent bioisostere was followed by a further derivatization to address hydrophobic region II. In combination with C-2 modifications of the imidazole core, we were able to design highly active inhibitors on the p38α MAP kinase. The inhibitor design presented herein represents a promising and highly efficient advancement of recent stages of development in this class of p38 MAP kinase inhibitors. In co…