Search results for "Vaccination."

Increasing Vaccine Acceptance and Uptake: A Review of the Evidence

2021

This article reviews the latest research on behavioral interventions to increase vaccine acceptance and uptake identifying the policies that work and underlying the determinants of their success. We focus primarily on studies that appeared after the publication of Brewer et al.’s (2017) in-depth survey of the behavioral literature on vaccination. We identify four major types of interventions that were tested in the lab, online or in the field: social norms-based interventions, opting-out strategies, reminders and recalls, and loss-framed/gain-framed messages (tailored to a particular population or not). Studies covered in this article can be a valuable resource to researchers as well as to …

Post H1N1 vaccination narcolepsy–cataplexy with decreased CSF beta-amyloid

2012

Vakcinācija priekšlaikus un laikā dzimušajiem bērniem Latvijā

2019

Ievads: Vakcinācija būtiski samazinājusi daudzu nopietnu slimību izplatību pasaulē. Lai gan priekšlaikus dzimuši zīdaiņi ir vairāk jutīgi pret infekcijām, viņu vakcinācija bieži vien tiek atlikta vai arī veikta pēc atvieglinātas programmas. Tā kā imunizācija Latvijā nav obligāta, ir nepieciešams pētījums, kurš ļaus atklāt aktuālas vakcinācijas tendences un faktorus, kas varētu uzlabot vakcinācijas pārklājumu. Mērķis: Šī pētījuma mērķis bija vakcināciju tendenču salīdzinājums priekšlaikus un laikā dzimušiem bērniem ar anonīmas vecāku aptauju. Metodoloģija: Bērnu (līdz pieciem gadiem) vecāki aizpildīja anketu (bērnu vecumu, dzimumu, dzimšanas datus un veselības stāvokli, pēcdzemdību hospitali…

Infection by Influenza Virus in Childhood: A Call for Broader Influenza Vaccination

2004

Efficiency of Biolistic DNA Vaccination in Experimental Type I Allergy

2012

Gene gun-mediated delivery of allergen-encoding plasmid DNA has been in focus for many years now as being a needle-free alternative to the protein-based desensitization regimen used in specific immunotherapy. Biolistic immunization with the Helios gene gun has proven to be potent in the induction of antigen-specific CD4(+) and CD8(+) T cells. Here we describe biolistic vaccination in experimental mouse models of IgE-mediated type I allergy as well as allergen-induced airway inflammation.

BNT162b vaccines are immunogenic and protect non-human primates against SARS-CoV-2

2020

AbstractA safe and effective vaccine against COVID-19 is urgently needed in quantities sufficient to immunise large populations. We report the preclinical development of two BNT162b vaccine candidates, which contain lipid-nanoparticle (LNP) formulated nucleoside-modified mRNA encoding SARS-CoV-2 spike glycoprotein-derived immunogens. BNT162b1 encodes a soluble, secreted, trimerised receptor-binding domain (RBD-foldon). BNT162b2 encodes the full-length transmembrane spike glycoprotein, locked in its prefusion conformation (P2 S). The flexibly tethered RBDs of the RBD-foldon bind ACE2 with high avidity. Approximately 20% of the P 2S trimers are in the two-RBD ‘down,’ one-RBD ‘up’ state. In mi…

"Kinderkrankheiten" 2002

2002

From epidemiology to public health decision making: analysis on IMD & vaccination strategy in Italy

2020

Abstract Introduction Invasive Meningococcal Disease (IMD) is one of the most severe vaccine-preventable disease, with high fatality rate and severe sequelae in up to 20% of survivors. MenB, MenC and MenACWY vaccines are available in Italy, but recommendations vary among Italian regions in terms of type of vaccines and targeted age groups. The aim of the study is to describe epidemiology of IMDs in order to provide the best vaccination strategy. Methods IMDs surveillance data in the period 2011-2017 from the Italian National Health Institute were explored. Excel was used to present trend analysis, stratifying by age and serogroups. Results In Italy, during the period 2011-2017, IMDs overall…

Intensity of the phenomenon of refusal to subject children to preventive vaccinations in the years 2002-2016 based on analysis of primary health care…

2018

Background. Vaccinations are the most effective method for preventing infectious diseases. Massive implementation of long-term vaccinations strategies has resulted in elimination or a reduced incidence of many infectious diseases. Aim of the study. To evaluate the intensity of the phenomenon of refusal to subject children to preventive vaccinations by attempting to characterize the parental group who refuse to vaccinate their children, determining the type and number of unrealized vaccinations, and identifying the reasons for being unvaccinated. Material and methods. The research material was medical records from the Non-Public Heath Care Unit in Opole. It concerned implementation of the Pr…

How should vaccination services be planned, organized, and managed? Results from a survey on the Italian vaccination services

2019

Background. Quality improvement is an increasingly recognized approach to maximize service effectiveness and minimize costs in public health. However, the Italian law never provided for the institutional accreditation of vaccination services. Furthermore, a recently approved law added six more compulsory vaccinations to the original four, which has led to a considerable increase in vaccination efforts, without any previous resources evaluation. The aim of the study was to investigate structural, organizational and managerial characteristics of the Italian vaccination services, in order to suggest the adoption of adequate quality standards. Study design. A survey involving the representative…