Search results for "Variant"
showing 10 items of 1267 documents
Measurement of the Effective Weak Mixing Angle inpp¯→Z/γ*→e+e−Events
2015
We present a measurement of the fundamental parameter of the standard model, the weak mixing angle, in $p\bar{p}\rightarrow Z/\gamma^{*}\rightarrow e^{+}e^{-}$ events at a center of mass energy of 1.96 TeV, using data corresponding to 9.7 fb$^{-1}$ of integrated luminosity collected by the D0 detector at the Fermilab Tevatron. The effective weak mixing angle is extracted from the forward-backward charge asymmetry as a function of the invariant mass around the Z boson pole. The measured value of $\sin^2\theta_{\text{eff}}^{\text{$\ell$}}=0.23146 \pm 0.00047$ is the most precise measurement from light quark interactions to date, with a precision close to the best LEP and SLD results.
A modeling study suggesting how a reduction in the context-dependent input on CA1 pyramidal neurons could generate schizophrenic behavior.
2011
The neural mechanisms underlying schizophrenic behavior are unknown and very difficult to investigate experimentally, although a few experimental and modeling studies suggested possible causes for some of the typical psychotic symptoms related to this disease. The brain region most involved in these processes seems to be the hippocampus, because of its critical role in establishing memories for objects or events in the context in which they occur. In particular, a hypofunction of the N-methyl-D-aspartate (NMDA) component of the synaptic input on the distal dendrites of CA1 pyramidal neurons has been suggested to play an important role for the emergence of schizophrenic behavior. Modeling st…
Impact of PNPLA3 and IFNL3 polymorphisms on hepatic steatosis in Asian patients with chronic hepatitis C.
2017
Background and aims A recent meta-analysis revealed that the genotype PNPLA3 rs738409 GG is associated with a higher risk of hepatic steatosis (HS) in Caucasian patients with chronic hepatitis C (CHC). However, controversial results were found regarding Asian populations. Furthermore, previous studies have shown a negative association between interferon lambda 3 (IFNL3) rs12979860 CC and HS in Caucasian CHC patients, but there have been no reports indicating any such association in Asian populations. In this study, then, we investigated the association of PNPLA3 and IFNL3 polymorphisms with HS in Asian CHC patients. Methods We enrolled consecutive CHC patients who underwent liver biopsy pri…
12q21 Interstitial Deletions: Seven New Syndromic Cases Detected by Array-CGH and Review of the Literature.
2022
Interstitial deletions of the long arm of chromosome 12 are rare, with a dozen patients carrying a deletion in 12q21 being reported. Recently a critical region (CR) has been delimited and could be responsible for the more commonly described clinical features, such as developmental delay/intellectual disability, congenital genitourinary and brain malformations. Other, less frequent, clinical signs do not seem to be correlated to the proposed CR. We present seven new patients harboring non-recurrent deletions ranging from 1 to 18.5 Mb differentially scattered across 12q21. Alongside more common clinical signs, some patients have rarer features such as heart defects, hearing loss, hypotonia an…
Wzorzec gatunkowy przewodnika turystycznego a realizacja tekstowa na przykładzie publikacji Jurija Nykołyszyna Lwów. Przewodnik
2021
W artykule przedstawiamy wyniki analizy realizacji tekstowej wzorca gatunkowego publikacji Jurija Nykołyszyna Lwów. Przewodnik. W części wstępnej przywołujemy teorię wzorca gatunkowego i jego wariantów kanonicznego, alternacyjnego i adaptacyjnego. Na tym tle pokazujemy przewodnik turystyczny jako gatunek. W kolejnych częściach omawiamy wyznaczniki gatunkowe analizowanego przewodnika: heterogeniczność, użytkowość, waloryzację i relacje nadawczo-odbiorcze. Analiza doprowadza do wniosku, że przewodnik Jurija Nykołyszyna jest wariantem alternacyjnym typowego przewodnika i charakteryzuje się jakościowymi i ilościowymi modyfikacjami kanonu.
Polynomimatriisit
2014
Tämän tutkielman sisältö voidaan karkeasti jakaa kahteen osaan. Ensimmäisessä on tarkoituksena tarkastella polynomimatriiseja ja erityisesti osoittaa toimiviksi kaksi niiden muokkaamiseen soveltuvaa algoritmia. Algoritmit toimivat osittain samalla idealla kuin lineaarialgebran perusteista tuttu Gaussin ja Jordanin menetelmä. Polynomit tuovat menetelmiin kuitenkin uutta sisältöä erityisesti jaollisuusominaisuuksiensa vuoksi. Tarkasteltavat matriisit ovat aina neliömatriiseja, ja polynomien kerroinkunnan karakteristika oletetaan nollaksi. Ensimmäinen algoritmi osoittaa, että Gaussin menetelmän polynomimatriiseille yleistetyillä rivioperaatioilla voidaan aina muokata polynomimatriisi yläkolmio…
Valutazione dei genotipi G6PD nella popolazione Siciliana e identificazione di una nuova variante: “G6PD*Palermo R257M”.
2008
La deficienza enzimatica di G6PDH è uno dei più comuni disordini nella popolazione siciliana in quanto più di 400 milioni di persone ne sono affette. Al fine di valutare la reale prevalenza dei casi nel nostro territorio presentiamo i dati di uno studio di genotipizzazione del locus G6PD (Xq28). 349 soggetti Siciliani di sesso maschile affetti da deficienza di G6PDH sono stati tipizzati secondo varie metodiche. Gli approcci di laboratorio sono: RFLPs (NlaIII, BclI, PstI e BspHI), PCR-Reverse Dot Blot (RDB) ed il sequenziamento diretto del gene. Le prime metodiche sono utili per definire le mutazioni già descritte e comunque le più comuni; il sequenziamento diretto è determinante per la valu…
Search for theX(4140)state inB+→J/ψϕK+decays
2012
We investigate the decay B+ -> J/psi phi K+ in a search for the X(4140) state, a narrow threshold resonance in the J/psi phi system. The data sample corresponds to an integrated luminosity of 10.4 fb(-1) of p (p) over bar collisions at root s = 1.96 TeV collected by the D0 experiment at the Fermilab Tevatron collider. We observe a mass peak with a statistical significance of 3.1 standard deviations and measure its invariant mass to be M = 4159.0 +/- 4.3(stat) +/- 6.6(syst) MeV and its width to be Gamma = 19.9 +/- 12.6(stat)(-8.0)(+3.0)(syst) MeV.
Histones, Their Variants and Post-translational Modifications in Zebrafish Development.
2020
Complex multi-cellular organisms are shaped starting from a single-celled zygote, owing to elaborate developmental programs. These programs involve several layers of regulation to orchestrate the establishment of progressively diverging cell type-specific gene expression patterns. In this scenario, epigenetic modifications of chromatin are central in influencing spatiotemporal patterns of gene transcription. In fact, it is generally recognized that epigenetic changes of chromatin states impact on the accessibility of genomic DNA to regulatory proteins. Several lines of evidence highlighted that zebrafish is an excellent vertebrate model for research purposes in the field of developmental ep…
Detecting multiple copies in tampered images
2010
Copy-move forgeries are parts of the image that are duplicated elsewhere into the same image, often after being modified by geometrical transformations. In this paper we present a method to detect these image alterations, using a SIFT-based approach. First we describe a state of the art SIFT-point matching method, which inspired our algorithm, then we compare it with our SIFT-based approach, which consists of three parts: keypoint clustering, cluster matching, and texture analysis. The goal is to find copies of the same object, i.e. clusters of points, rather than points that match. Cluster matching proves to give better results than single point matching, since it returns a complete and co…