Search results for "Vascularization"
showing 10 items of 519 documents
Critical limb ischaemia: definition and natural hystory
2004
The term critical limb ischemia refers to a condition characterized by chronic ischemic at-rest pain, ulcers, or gangrene in one or both legs attributable to objectively proven arterial occlusive disease. Critical limb ischemia implies chronicity and is to be distinguished from acute limb ischemia. Its incidence is approximately 500 to 1000 per million year, with the highest rates among older subjects, smokers and diabetics. The rate of primary amputation ranges from 10% to 40%, and was performed only when no graftable distal vessels were present, or in neurologically impaired or hopelessly nonambulatory patients. Contrarily, in some highly specialized and aggressive centres about 90% of pa…
Reduced Admissions for Cerebrovascular Events during COVID-19 Outbreak in Italy
2020
Supplemental Digital Content is available in the text.
New Technique in Tendon Sport Recovery. Percutaneous Electrolysis Intratissue (EPI®)
2013
Based on the literature and clinical experience we know that the technique of percutaneous electrolysis intratissue (EPI ® ) has positive effects on the recovery of human tendinopathies. The application of the technique, together with the completion of eccentric exercise, give benefits leading to anatomical and functional recovery in the tendon that can be appreciated by ultrasound using the scale of "Victorian Institute of Sport Assessment-patellar tendon" (VISA-P). Due to clinical knowledge, damage to tendon is accompanied by increase in oxidative stress, cell death and inflammation at the damaged area. The EPI ® technique produced a galvanic current inside the tendon, with an acupuncture…
Evaluation of PAI-1 in endometriosis using a homologous immunocompetent mouse model
2018
To analyze the role of PAI-1 (plasminogen activator inhibitor 1) in endometriotic lesion growth, we studied the effect of PAI-1 inhibition by PAI-039 using a homologous mouse model of endometriosis that allows noninvasive monitoring. Endometrial tissue from donor mice was collected, labeled with mCherry adenovirus, and implanted into a subcutaneous pocket on the ventral abdomen of recipient mice. Seven days after transplantation, mice were randomly allocated in two groups and treated once daily for 2 weeks with either vehicle (control group) or PAI-1 inhibitor (PAI-039 group). Endometriotic lesion size generated in recipient mice was monitored by mCherry signal. Animals were euthanized 21 d…
Visual Health Nanocomposites: Present and Future
2021
Background: In recent years, the therapeutics for eye diseases as retinopathy diabetic, dry eye, glaucoma and contact lenses fabrication are including nanocompounds as ocular drug delivery systems, biomarkers for detection of eye diseases, copper and silver ions that has been incorporated by means of the nanotechnology for the production of less toxic and more effective alternatives. Several compounds such as silver nanoparticles, turmeric-based nanocomposites, neovascularization blockers and nanoparticles extracted from the plant Costus pictus among others have been researched for this purpose. Those compounds are some of the promising research efforts that are studying and will contribute…
Tierexperimentelle untersuchungen zur rolle von entzündungsmediatoren bei der hornhautneovaskularisation
1984
Experimental investigations concerning the role of inflammatory compounds in corneal neovascularization.Natural and synthetic inflammatory compounds were implanted in the corneas of rabbits to clarify the question whether corneal neovascularization is induced by stromal edema alone, or by neovascular mediators. It could be demonstrated that prostaglandin E1 and E2 have an angiogenetic capacity, whereas their precursor (arachidonic acid) as well as PGA1, A2, B2, I2 and Thromboxan A2 were inactive in this regard.Histology showed that corneal neovascularization is always accompanied by the invasion of polymorphonuclear leukocytes. Corneal edema in the beginning of vascularization can be explai…
Beals–Hecht syndrome and choroidal neovascularization
2010
Purpose: To describe a case of choroidal neovascularization (CNV) in a female diagnosed with Beals–Hecht syndrome. Methods: A retrospective, interventional case is described in a 26-year-old female complaining of metamorphopsia and visual loss in her left eye (counting fingers). The fluorescein angiogram and the optical coherence tomography supported the diagnosis of CNV. Intravitreal ranibizumab was administered. Results: After the third intravitreal ranibizumab, her visual acuity improved to 0.8 and the morphology of the macular area was restored. Conclusions: To our knowledge this is the first report of CNV in Beals–Hecht syndrome treated with ranibizumab. Self-monitoring by periodically…
Operācijas rezultātu korelācija ar miega artērijas revaskularizācijas metodēm
2014
Anotācija Miega artēriju stenozes ķirurģiskai korekcijai karotīdu endarterectomijai ir būtiska nozīme insulta profilaksē. Promocijas darba mērķis: Izvērtēt miega artērijas endarterektomiju operāciju rezultātus, ņemot vērā intima-media slāņa biezumu un pacienta dzīves kvalitāti. Promocijas darbā autore veikusi pētījumu, kas atspoguļo karotīdu endarterektomijas operāciju rezultātus (komplikācijas, dzīves kvalitātes izmaiņas) un intīmas hiperplāzijas attīstību postoperatīvā periodā. Izveidota speciāla dzīves kvalitātes novērtēšanas anketa pacientiem ar miega artērijas sašaurinājumu. Pētījuma materiālu veido 104 pacienti, kuriem veiktas karotīdu endarterektomijas. Darbs veikts Latvijas Universi…
Pressor amines in coronary artery bypass grafting procedure with and without the use of extracorporeal circulation
2017
Wstęp: Operacje rewaskularyzacji mięśnia sercowego są najczęściej wykonywanymi procedurami w praktyce kardiochirurgicznej. Rozwój technik pomostowania tętnic wieńcowych bez użycia krążenia pozaustrojowego spowodował, iż modyfikacjom uległy również techniki znieczulenia. W prowadzeniu znieczulenia do zabiegów typu OPCA B anestezjolog musi szczególnie szybko reagować na częste, czasem nieprzewidywalne zmiany sytuacji hemodynamicznej. Cel pracy: Celem pracy było porównanie zastosowania amin presyjnych wśród pacjentów poddanych chirurgicznej rewaskularyzacji mięśnia sercowego z krążeniem pozaustrojowym i bez niego. Materiał i metody: Badanie miało charakter retrospektywny. Badaniem objęto 80 ch…
Carga de comorbilidad y beneficio de la revascularización en ancianos con síndrome coronario agudo
2021
Introduction and objectives: To evaluate the interaction between comorbidity burden and the benefits of in-hospital revascularization in elderly patients with non-ST-segment elevation acute coronary syndrome (NSTEACS). Methods: This retrospective study included 7211 patients aged ≥ 70 years from 11 Spanish NSTEACS registries. Six comorbidities were evaluated: diabetes, peripheral artery disease, cerebrovascular disease, chronic pulmonary disease, renal failure, and anemia. A propensity score was estimated to enable an adjusted comparison of in-hospital revascularization and conservative management. The end point was 1-year all-cause mortality. Results: In total, 1090 patients (15%) died. Th…