Search results for "Viscosity"
showing 10 items of 542 documents
Bifunctional viscous nanovesicles co-loaded with resveratrol and gallic acid for skin protection against microbial and oxidative injuries.
2017
Resveratrol and gallic acid were co-loaded in phospholipid vesicles aiming at protecting the skin from external injuries, such as oxidative stress and microbial infections. Liposomes were prepared using biocompatible phospholipids dispersed in water. To improve vesicle stability and applicability, the phospholipids and the phenols were dispersed in water/propylene glycol or water/glycerol, thus obtaining PEVs and glycerosomes, respectively. The vesicles were characterized by size, morphology, physical stability, and their therapeutic efficacy was investigated in vitro. The vesicles were spherical, unilamellar and small in size: liposomes and glycerosomes were around 70nm in diameter, while …
Fluorescence Probes Exhibit Photoinduced Structural Planarization: Sensing In Vitro and In Vivo Microscopic Dynamics of Viscosity Free from Polarity …
2020
We demonstrate the construction of wavelength λ-ratiometric images that allow visualizing the distribution of microscopic dynamics within living cells and tissues by using the newly developed principle of fluorescence response. The bent-to-planar motion in the excited state of incorporated fluorescence probes leads to elongation of the π-delocalization, resulting in microviscosity-dependent but polarity-insensitive interplay between well-separated blue and red bands in emission spectra. This allows constructing the exceptionally contrasted images of cellular dynamics. Moreover, the application of probes with increased affinity toward biological membranes allowed detecting the differences in…
Design and protocol of Estrogenic Regulation of Muscle Apoptosis (ERMA) study with 47 to 55-year-old women's cohort : novel results show menopause-re…
2018
Supplemental Digital Content is available in the text
Reflections on the unexpected laboratory finding of hemorheological alterations observed in some haematological disorders
2021
Hyperviscosity syndrome is a clinical condition characterized by the slowing of blood flow through the vessels and it may be associated with several diseases. The nosographic classification of primary hyperviscosity conditions (Wells classification 1970) divided the primary hyperviscosity syndromes in polycythaemic, sclerocytemic and sieric. Recent and personal laboratory observations have highlighted an unexpected behaviour of the erythrocyte deformability observed in some haematological disorders such as polycythemia vera, multiple myeloma and monoclonal gammopathy of undetermined significance. The interest of this observation depends on the fact that up to now, according to the Wells cla…
A continuous time tug-of-war game for parabolic $p(x,t)$-Laplace type equations
2019
We formulate a stochastic differential game in continuous time that represents the unique viscosity solution to a terminal value problem for a parabolic partial differential equation involving the normalized $p(x,t)$-Laplace operator. Our game is formulated in a way that covers the full range $1<p(x,t)<\infty$. Furthermore, we prove the uniqueness of viscosity solutions to our equation in the whole space under suitable assumptions.
Are we correctly measuring the rotational viscosity of heterogeneous bituminous binders?
2020
Modified bituminous binders allow asphalt technologists to design asphalt mixtures with superior performance. However, several recent studies highlighted that due to the complexity of these material, their characterisation can be challenging since common procedures used to characterise neat bitumen might not be adequate. For instance, during high temperature rotational viscosity testing of recycled tyre rubber modified binders (RTR-MB), a number of changes may occur to the sample leading to the here-defined sample stability which in turn provides misleading results. In this study the authors want to first provide a deeper understanding of this phenomenon by a numerical analysis using a besp…
Rheological characterisation of cold bitumen emulsion slurries
2021
The performance of cold bitumen emulsion (CBE) mixtures is strongly linked to an optimised design of the binder blends and mastics. Types and dosages of bitumen, mineral additions and the workability must be characterised and optimised. This study aims at providing an approach for the fundamental characterisation of CBE materials using rotational viscometry. Firstly, a procedure for measuring the viscosity of CBE slurries using the Brookfield viscometer was investigated by comparing results obtained by using a traditional spindle geometry and a novel impeller engineered to avoid phase separation: the dual helical ribbon (DHR). Afterwards, the effect of mineral additions and bitumen emulsion…
Densities, Viscosities, and Refractive Indices of the Binary Systems Methyl tert-Butyl Ether + 2-Methylpentane, + 3-Methylpentane, + 2,3-Dimethylpent…
2000
This paper reports experimental densities, viscosities, and refractive indices of the binary systems methyl tert-butyl ether (MTBE) + 2-methylpentane, + 3-methylpentane, + 2,3-dimethylpentane, and + 2,2,4-trimethylpentane over the entire range of composition, at 298.15 K and atmospheric pressure. Excess molar volumes and viscosity deviations were evaluated from the experimental data. These excess or derived properties were fitted to the Redlich−Kister equation to estimate the binary interaction parameters. The experimental values of viscosity have been compared to values predicted by means of the GC−UNIMOD model.
Characterizing the initial conditions of heavy-ion collisions at the LHC with mean transverse momentum and anisotropic flow correlations
2022
Physics letters / B 834, 137393 (2022). doi:10.1016/j.physletb.2022.137393
Viscosity-mediated negative food effect on oral absorption of poorly-permeable drugs with an absorption window in the proximal intestine: In vitro ex…
2014
Concomitant food intake can diminish oral absorption of drugs with limited permeability and an absorption window in the proximal intestine, due to viscosity-mediated decrease in dosage form disintegration time and drug dissolution rate. Three poorly-permeable drugs (atenolol, metformin hydrochloride, and furosemide) exhibiting negative food effect, and one highly-soluble and highly-permeable (metoprolol tartrate), serving as a negative control, were selected for the study. In vitro and in silico tools were used to evaluate the influence of media viscosity on drug bioperformance under fasted and fed conditions. The obtained results demonstrated that increased medium viscosity in the presence…