Search results for "Vitamina"
showing 10 items of 44 documents
Vitamin D and Cardiovascular Health
2021
The principal source of vitamin D in humans is its biosynthesis in the skin through a chemical reaction dependent on sun exposure. In lesser amounts, the vitamin can be obtained from the diet, mostly from fatty fish, fish liver oil and mushrooms. Individuals with vitamin D deficiency, defined as a serum level of 25 hydroxyvitamin D < 20 ng/dl, should be supplemented. Vitamin D deficiency is a prevalent global problem caused mainly by low exposure to sunlight. The main role of 1,25 dihydroxyvitamin D is the maintenance of calcium and phosphorus homeostasis. However, vitamin D receptors are found in most human cells and tissues, indicating many extra-skeletal effects of the vitamin, particula…
Two known therapies could be useful as adjuvant therapy in critical patients infected by COVID-19☆
2020
Pneumonia caused by coronavirus, which originated in Wuhan, China, in late 2019, has been spread around the world already becoming a pandemic. Unfortunately, there is not yet a specific vaccine or effective antiviral drug for treating COVID-19. Many of these patients deteriorate rapidly and require intubation and are mechanically ventilated, which is causing the collapse of the health system in many countries due to lack of ventilators and intensive care beds. In this document we review two simple adjuvant therapies to administer, without side effects, and low cost that could be useful for the treatment of acute severe coronavirus infection associated with acute respiratory syndrome (SARS-C…
Co-Loading of Ascorbic Acid and Tocopherol in Eudragit-Nutriosomes to Counteract Intestinal Oxidative Stress
2019
The present study aimed at developing a new vesicular formulation capable of promoting the protective effect of ascorbic acid and tocopherol against intestinal oxidative stress damage, and their efficacy in intestinal wound healing upon oral administration. A pH-dependent copolymer (Eudragit®
Vitamin D, precocious acute myocardial infarction, and exceptional longevity
2015
Recent studies have reported low circulating levels of 25-hydroxyvitamin D (25(OH)D), the biologically active form of vitamin D, in patients with cardiovascular disease (CVD) [1], hypertension [2], carotid atherosclerosis [3], atrial fibrillation [4], and heart failure [5]. Moreover, vitamin D deficiency has been associated with all-cause mortality [6,7] and predicts adverse cardiac events in patients with established CVD [8] or after acute myocardial infarction (AMI) [9]. In turn, vitamin D supplementation improves the modulation of autonomic tone [10]. 4.638 JCR (2015) Q1, 24/124 Cardiac and cardiovascular systems UEM
La eclosión de la sarcopenia: Informe preliminar del Observatorio de la Sarcopenia de la Sociedad Española de Geriatría y Gerontología
2011
Resumen La sarcopenia es un sindrome geriatrico frecuente e importante para la practica clinica diaria de los profesionales que trabajan con personas mayores. El numero de personas mayores afectadas y su relacion con la incapacidad, la fragilidad, muchas enfermedades, habitos de vida y resultados adversos son de gran relevancia para la practica geriatrica. Ademas, los cambios biologicos que conducen a la perdida de fuerza y masa muscular se relacionan intrinsecamente con los mecanismos del envejecimiento. No es, por tanto, sorprendente que la investigacion en este campo este creciendo exponencialmente en los ultimos anos y que la sarcopenia se haya colocado en los ultimos anos en el primer …
Evaluación antropométrica del estado nutricional y estimación de las ingestas de hierro y de vitamina C de mujeres posmenopáusicas y hombres mayores …
2001
Carmen.Vidal@uv.es Objetivo: Evaluación del estado nutricional de mujeres posmenopáusicas y hombres mayores de 45 años, mediante medidas antropométricas, y estimación de las fuentes e ingestas dietéticas de hierro y de vitamina C. Material y métodos: Participan en el estudio 125 hombres y 176 mujeres de 40 a 93 años procedentes de dos Centros de Salud y del Centro de Hemodonación de Cartagena (Murcia). Se realiza una valoración antropométrica y una encuesta alimentaria de frecuencia de consumo de alimentos durante el último mes. Los contenidos de hierro y de vitamina C se obtienen de las tablas de composición de alimentos españoles. Para evaluar la dieta con respecto al hierro y la vitamina…
A new role of CYP2R1 in Multiple Sclerosis
2018
Review: Determination of Vitamin D in Dairy Products by High Performance Liquid Chromatography
2005
This work reviews the methods used for the determination of vitamin D in some dairy products (milk and infant formulas) by high performance liquid chromatography (HPLC). The low vitamin D contents and the presence of interfering compounds require sample treatment and purification of the extract. The advantages and drawbacks of hot and cold saponification, direct extraction and different types of extract purification are also discussed, taking into account the lack of vitamin D stability by heating, exposure to light and oxidation. With respect to chromatographic determination, the mode (normal or reverse phase), type of column (microcolumn or conventional) and detection system (UV, electro…
“AD HOC” MODIFIED CLAYS FOR BIOTECHNOLOGICAL APPLICATIONS
Nowadays, the scientific community has to face with cogent problems strictly linked to the improvement of quality of live. Among the different tasks to achieve the prefixed objective the focus has been put on the drug administration, i.e., attention has been paid to propose an appropriate solution to improve the performance of a drug delivery system and to eliminate both the side effect and drawbacks. With the aim to achieve the design, synthesis, and characterization of versatile systems, with peculiar characteristics, based on clays and clays modified with a biocompatible surfactant, able to adsorb and release organic substances of pharmaceutical interest the present PhD thesis has been u…