Search results for "XOS"
showing 10 items of 414 documents
State, law and gender studies
2003
La formación del estado y su ordenamiento jurídico se ha realizado por los varones con exclusión de las mujeres, la igualdad entre los hombres y las mujeres no ha sido un principio fundamental del derecho ni del sistema político. El derecho a la igualdad descansa sobre presupuestos de naturaleza cultural y filosófica que tratan al hombre como el sujeto universal y a la mujer como una categoría específica. La teoría feminista del derecho coincide en la crítica de estos presupuestos pero existen grandes diferencias en cuanto se pretende abordar un modelo teórico alternativo para resolver la desigualdad de género-sexo. La aprobación de la Constitución, la adaptación del ordenamiento jurídico a…
Debate de los sexos y discursos de progreso en la Ilustración española
2009
Al menos desde el siglo XVIII, los discursos que expresan una autoconciencia de modernidad, o sea, aquellos que, de una forma u otra, se plantean como tarea sisematizar los rasgos sociales característicos del progreso (o bien los indicativos de su carencia) y proporcionar diagnósticos y soluciones para el desarrollo (económico, político, cultural o social) de las sociedades han incorporado entre sus criterios de análisis las relaciones entre los sexos, es decir, han incluido esa variable entre los principales rasgos que se considera necesario conocer de una sociedad para formarse un juicio acerca de sus logros o sus problemas y entre los factores que toda colectividad que se pretenda modern…
Evidence for the presence of collagenous domains in Candida albicans cell surface proteins
1995
Rabbit polyclonal antibodies (PAbs) directed towards the amino-terminal cysteine-rich 7S domain (PAb anti-7S), the major internal collagenous domain (PAb anti-type IV), and the C-terminal noncollagenous region (PAb anti-NC1) of the type IV collagen molecule were probed by indirect immunofluorescence against Candida albicans blastoconidia and germinated blastoconidia. Most nongerminating cells and mother blastoconidia from which germ tubes originated showed strong fluorescence when PAb anti-7S was used, whereas with PAb anti-type IV, fluorescence was found almost exclusively on the surface of filamentous forms. A patched fluorescent pattern rather than a homogenous confluent fluorescence was…
La agenda oculta del trabajo invisible: aproximación teórica y categorización
2015
<p>Los estudios sobre corresponsabilidad en el trabajo doméstico y en la sostenibilidad de la vida han valorado las desigualdades entre hombre y mujeres en el reparto de las funciones domésticas y de cuidado, pero —hasta el momento— han dejado de lado algunas tareas que por sus características resultan más difusas. Nuestra investigación pretende comprobar cuáles son las tareas que siguen siendo invisibles actualmente, de modo que puedan ser incorporadas para futuros análisis y colaborar, con esta visibilización, a su consideración social y a la corresponsabilidad plena como aspiración imprescindible de igualdad entre sexos.</p>
Improving extracellular vesicles visualization: From static to motion
2020
AbstractIn the last decade, extracellular vesicles (EVs) have become a hot topic. The findings on EVs content and effects have made them a major field of interest in cancer research. EVs, are able to be internalized through integrins expressed in parental cells, in a tissue specific manner, as a key step of cancer progression and pre-metastatic niche formation. However, this specificity might lead to new opportunities in cancer treatment by using EVs as devices for drug delivery. For future applications of EVs in cancer, improved protocols and methods for EVs isolation and visualization are required. Our group has put efforts on developing a protocol able to track the EVs for in vivo intern…
Intracellular trafficking of endogenous fibroblast growth factor‐2
2008
We have previously reported how the release of fibroblast growth factor-2 (FGF-2) is mediated by shed vesicles. In the present study, we address the question of how newly synthesized FGF-2 is targeted to the budding vesicles. Considering that in vitro cultured Sk-Hep1 hepatocarcinoma cells release FGF-2 and shed membrane vesicles only when cultured in the presence of serum, we added serum to starved cells and monitored intracellular movements of the growth factor. FGF-2 was targeted both to the cell periphery and to the nucleus and nucleolus. Movements toward the cell periphery were not influenced by drugs affecting microtubules, but were inhibited by cytocalasin B. Involvement of actin in …
P2.07: Evaluation of Different Exosomal RNA Isolation Methods in NSCLC Liquid Biopsies: Track: Biology and Pathogenesis
2016
Peris de Sales, Vicent; Parra Monserrat, David; Souto González, Xosé Manuel (coords.) (2018): Repensamos la geografía e historia para la educación de…
2019
Exosomes released by keratinocytes modulate melanocyte pigmentation
2015
Cells secrete extracellular vesicles (EVs), exosomes and microvesicles, which transfer proteins, lipids and RNAs to regulate recipient cell functions. Skin pigmentation relies on a tight dialogue between keratinocytes and melanocytes in the epidermis. Here we report that exosomes secreted by keratinocytes enhance melanin synthesis by increasing both the expression and activity of melanosomal proteins. Furthermore, we show that the function of keratinocyte-derived exosomes is phototype-dependent and is modulated by ultraviolet B. In sum, this study uncovers an important physiological function for exosomes in human pigmentation and opens new avenues in our understanding of how pigmentation is…
Cuticle: Formation, Moulting and Control
1984
The relative rigidity of the arthropod exoskeleton makes it impossible for body size to increase continuously during the postembryonic development of these animals. Once they have hatched from the egg, they grow in steps, passing through a variable number of (larval) stages (Fig. 1 a). Apart from a few exceptions, there are between 3 and 10 such stages in the arachnids, 3–20 in the crustaceans, and 3–10 in the insects. In many cases a metamorphosis stage intervenes (some crustaceans; holometabolous insects) (Fig. 9b, c).